US3899493A
(en)
*
|
1972-12-29 |
1975-08-12 |
Richter Gedeon Vegyeszet |
Chromic acid oxidation of vinblastine sulfate to form vincristine
|
HU165986B
(US07534539-20090519-C00280.png)
*
|
1973-02-16 |
1974-12-28 |
|
|
US4012390A
(en)
*
|
1974-10-16 |
1977-03-15 |
Eli Lilly And Company |
Vinblastinoic acid
|
US3954773A
(en)
*
|
1974-11-21 |
1976-05-04 |
Eli Lilly And Company |
4-Desacetoxyvinblastine
|
US3944554A
(en)
*
|
1975-01-09 |
1976-03-16 |
Eli Lilly And Company |
4-Desacetoxy-3-hydroxyvinblastine
|
US4029663A
(en)
*
|
1975-07-10 |
1977-06-14 |
Eli Lilly And Company |
Dimeric anhydro-vinca derivatives
|
US4209443A
(en)
*
|
1976-02-13 |
1980-06-24 |
Richter Gedeon Vegyeszeti Gyar Rt. |
Process for separating pharmaceutically active diindole alkaloids
|
US4143041A
(en)
*
|
1977-01-19 |
1979-03-06 |
Eli Lilly And Company |
4'-Deoxyvincristine and related compounds
|
HU178084B
(en)
*
|
1977-05-31 |
1982-03-28 |
Richter Gedeon Vegyeszet |
New process for the extraction of native vindoline,catharantine,3',4'-anhydrovinblastine,leurosine and,if desired,of other diinodle alkaloids from vinca rosea l.drogue
|
US4195022A
(en)
*
|
1978-03-27 |
1980-03-25 |
Eli Lilly And Company |
4-Desacetoxy-4α-hydroxyvinblastine and related compounds
|
US4166810A
(en)
*
|
1978-04-20 |
1979-09-04 |
Eli Lilly And Company |
Derivatives of 4-desacetyl VLB C-3 carboxyhydrazide
|
HU178706B
(en)
*
|
1979-04-23 |
1982-06-28 |
Richter Gedeon Vegyeszet |
Process for preparing bis-indole alkaloids and acid addition salts thereof
|
FR2461714A1
(fr)
|
1979-07-17 |
1981-02-06 |
Anvar |
Nouvelle classe de composes bis-indoliques utiles comme medicaments et procede pour leur preparation
|
EP0123441B1
(en)
*
|
1983-03-30 |
1990-10-03 |
Lilly Industries Limited |
Vincaleukoblastine derivatives
|
US4522750A
(en)
*
|
1984-02-21 |
1985-06-11 |
Eli Lilly And Company |
Cytotoxic compositions of transferrin coupled to vinca alkaloids
|
HU198074B
(en)
*
|
1985-06-12 |
1989-07-28 |
Richter Gedeon Vegyeszet |
Process for producing new bis-indole derivatives and pharmaceutical compositions comprising these compounds
|
HU193318B
(en)
*
|
1985-06-12 |
1987-09-28 |
Richter Gedeon Vegyeszet |
Process for producing new bis- indol derivatives
|
US4667030A
(en)
*
|
1985-06-17 |
1987-05-19 |
Eli Lilly And Company |
Hydrazide succinimide derivatives of antineoplastic indole-dihydroindole alkaloids
|
US4801688A
(en)
*
|
1986-05-27 |
1989-01-31 |
Eli Lilly And Company |
Hydrazone immunoglobulin conjugates
|
HUT76925A
(hu)
*
|
1995-04-04 |
1998-01-28 |
MTA Enzimológiai Intézet |
Bisz-indol-származékok, eljárás előállításukra és az azokat tartalmazó gyógyszerkészítmények
|
US6326402B1
(en)
|
1998-08-12 |
2001-12-04 |
Octamer, Inc. |
Methods for treating viral infections using a compound capable of inhibiting microtubules
|
WO2002085908A1
(en)
*
|
2001-04-24 |
2002-10-31 |
Purdue Research Foundation |
Folate mimetics and folate-receptor binding conjugates thereof
|
WO2003097647A1
(en)
*
|
2002-05-15 |
2003-11-27 |
Endocyte, Inc. |
Vitamin-mitomycin conjugates
|
CA2512867C
(en)
|
2003-01-27 |
2014-08-26 |
Endocyte, Inc. |
Vitamin receptor binding drug delivery conjugates
|
US8288557B2
(en)
*
|
2004-07-23 |
2012-10-16 |
Endocyte, Inc. |
Bivalent linkers and conjugates thereof
|
JP5289935B2
(ja)
*
|
2005-03-16 |
2013-09-11 |
エンドサイト,インコーポレイテッド |
プテロイン酸およびその結合体の合成と精製
|
KR101364912B1
(ko)
*
|
2005-08-19 |
2014-02-21 |
엔도사이트, 인코포레이티드 |
복수-약제 리간드 공액체
|
EP2382995A3
(en)
|
2005-08-19 |
2013-09-25 |
Endocyte, Inc. |
Ligand conjugates of Vinca alkaloids, analogs and derivatives
|
US20100104626A1
(en)
*
|
2007-02-16 |
2010-04-29 |
Endocyte, Inc. |
Methods and compositions for treating and diagnosing kidney disease
|
CN104127878A
(zh)
*
|
2007-03-14 |
2014-11-05 |
恩多塞特公司 |
结合配体连接的微管溶素递药缀合物
|
JP5690589B2
(ja)
*
|
2007-06-25 |
2015-03-25 |
エンドサイト・インコーポレイテッドEndocyte, Inc. |
親水性スペーサーリンカーを含有する結合体
|
US9877965B2
(en)
|
2007-06-25 |
2018-01-30 |
Endocyte, Inc. |
Vitamin receptor drug delivery conjugates for treating inflammation
|
JP2011500835A
(ja)
|
2007-10-25 |
2011-01-06 |
エンドサイト,インコーポレイテッド |
チューブリシン類および調製プロセス
|
WO2013126797A1
(en)
|
2012-02-24 |
2013-08-29 |
Purdue Research Foundation |
Cholecystokinin b receptor targeting for imaging and therapy
|
US20140080175A1
(en)
|
2012-03-29 |
2014-03-20 |
Endocyte, Inc. |
Processes for preparing tubulysin derivatives and conjugates thereof
|
CN104869998A
(zh)
|
2012-10-16 |
2015-08-26 |
恩多塞特公司 |
含有非天然氨基酸的药物递送缀合物以及其使用方法
|