BE606063A - Dérivés thiadiaziniques et leur préparation. - Google Patents

Dérivés thiadiaziniques et leur préparation.

Info

Publication number
BE606063A
BE606063A BE606063A BE606063A BE606063A BE 606063 A BE606063 A BE 606063A BE 606063 A BE606063 A BE 606063A BE 606063 A BE606063 A BE 606063A BE 606063 A BE606063 A BE 606063A
Authority
BE
Belgium
Prior art keywords
preparation
thiadiazine derivatives
thiadiazine
derivatives
Prior art date
Application number
BE606063A
Other languages
English (en)
French (fr)
Inventor
James Michael Mcmanus
William Merrill Mclamore
Original Assignee
Pfizer & Co C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer & Co C filed Critical Pfizer & Co C
Publication of BE606063A publication Critical patent/BE606063A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/15—Six-membered rings
    • C07D285/16—Thiadiazines; Hydrogenated thiadiazines
    • C07D285/18—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines
    • C07D285/20—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems
    • C07D285/22—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D285/24—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom
    • C07D285/26—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom substituted in position 6 or 7 by sulfamoyl or substituted sulfamoyl radicals
    • C07D285/30—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom substituted in position 6 or 7 by sulfamoyl or substituted sulfamoyl radicals with hydrocarbon radicals, substituted by hetero atoms, attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04D—NON-POSITIVE-DISPLACEMENT PUMPS
    • F04D29/00—Details, component parts, or accessories
    • F04D29/08—Sealings
    • F04D29/10—Shaft sealings
    • F04D29/12—Shaft sealings using sealing-rings
    • F04D29/126—Shaft sealings using sealing-rings especially adapted for liquid pumps
    • F04D29/128—Shaft sealings using sealing-rings especially adapted for liquid pumps with special means for adducting cooling or sealing fluid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mechanical Engineering (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Structures Of Non-Positive Displacement Pumps (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
BE606063A 1960-09-27 1961-07-12 Dérivés thiadiaziniques et leur préparation. BE606063A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58632A US3102882A (en) 1960-09-27 1960-09-27 Derivatives of 3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide
GB991/61A GB902658A (en) 1960-09-27 1961-01-10 6-substituted (or unsubstituted) 2-alkyl-3-allylthiomethyl-7-sulphamyl-3,4-dihydrobenzothiadiazine dioxides and process for preparation

Publications (1)

Publication Number Publication Date
BE606063A true BE606063A (fr) 1962-01-12

Family

ID=26236340

Family Applications (1)

Application Number Title Priority Date Filing Date
BE606063A BE606063A (fr) 1960-09-27 1961-07-12 Dérivés thiadiaziniques et leur préparation.

Country Status (6)

Country Link
US (1) US3102882A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE606063A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (2) DE1445121A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES270748A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR1426M (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (2) GB902658A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3265573A (en) * 1962-07-27 1966-08-09 Squibb & Sons Inc Benzothiadiazinesulfonamide-1, 1-dioxide composition
US3251837A (en) * 1962-09-14 1966-05-17 Pfizer & Co C Derivatives of 1, 2, 4-benzothiadiazine-1, 1-dioxides
US4338435A (en) * 1981-06-01 1982-07-06 E. R. Squibb & Sons, Inc. Benzothiadiazines having diuretic activity
US6982251B2 (en) 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
AR035533A1 (es) 2001-01-26 2004-06-02 Schering Corp Uso de por lo menos un inhibidor de la absorcion de los esteroles o sus sales, solvatos, prodrogas farmaceuticamente aceptables o mezclas de los mismos para la preparacion de un medicamento para el tratamiento de la sitosterolemia, composiciones farmaceuticas, el uso de dichas composiciones para la
US7071181B2 (en) 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
SK287988B6 (sk) 2001-01-26 2012-09-03 Schering Corporation Composition, oral dosage form and use thereof
US7056906B2 (en) 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
AU2002336609B2 (en) 2001-09-21 2006-08-24 Merck Sharp & Dohme Corp. Treatment of xanthoma with azetidinone derivatives as sterol absorption inhibitors
US7053080B2 (en) 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
KR100668539B1 (ko) 2002-08-19 2007-01-16 화이자 프로덕츠 인크. 과증식성 질환에 대한 조합요법
WO2004043457A1 (en) 2002-11-06 2004-05-27 Schering Corporation Cholesterol absorptions inhibitors for the treatment of autoimmune disorders
MXPA05009502A (es) 2003-03-07 2005-10-18 Schering Corp Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.
EP1601669B1 (en) 2003-03-07 2008-12-24 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
US7459442B2 (en) 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
WO2004081002A1 (en) 2003-03-07 2004-09-23 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
US20060063803A1 (en) * 2004-09-23 2006-03-23 Pfizer Inc 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
EP2094643B1 (en) 2006-12-01 2012-02-29 Bristol-Myers Squibb Company N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as cetp inhibitors for the treatment of atherosclerosis and cardiovascular diseases
EP2998314B1 (en) 2007-06-04 2020-01-22 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EP2328910B1 (en) 2008-06-04 2014-08-06 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
CA2730603C (en) 2008-07-16 2019-09-24 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
WO2014151206A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
EP2968439A2 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
RS65632B1 (sr) 2013-06-05 2024-07-31 Bausch Health Ireland Ltd Ultra-prečišćeni agonisti guanilat-ciklaze c, postupak njihove pripreme i upotrebe
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
EP3911648B1 (en) 2019-01-18 2024-10-23 Astrazeneca AB 6'-[[(1s,3s)-3-[[5-(difluoromethoxy)-2-pyrimidinyl]amino]cyclopentyl]amino][1(2h),3'-bipyridin]-2-one as pcsk9 inhibitor and methods of use thereof

Also Published As

Publication number Publication date
ES270748A1 (es) 1961-12-16
FR1426M (fr) 1962-08-06
GB902658A (en) 1962-08-09
DE1445121A1 (de) 1968-11-28
DE1302648B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB905137A (en) 1962-09-05
US3102882A (en) 1963-09-03

Similar Documents

Publication Publication Date Title
BE606063A (fr) Dérivés thiadiaziniques et leur préparation.
FR1271180A (fr) Cyclododécylguanidine et ses dérivés et leur préparation
BE602888A (fr) Nouveaux dérivés de 8-benzylxanthines et leur préparation.
BE611000A (fr) Dérivés de benzazocines et leur préparation
BE607171A (fr) Dérivés d'alanine et leur préparation
FR1288907A (fr) Dérivés de cystéine et leur préparation
OA00151A (fr) Nouveaux dérivés pyrazolidiniques et leur préparation.
OA01362A (fr) Nouvelles phényl-alkylamines et leur préparation.
FR1336070A (fr) Dérivés de la phénoxazine et leur préparation
BE604996A (fr) Dérivés de la 1,2,3,4-tétrahydroquinazolinone et leur préparation
BE608433A (fr) Nouvelles morpholinones et leur préparation.
FR1302943A (fr) Benzylguanidines et leur préparation
FR1445453A (fr) Phénylcyclopropyl-amides et leur préparation
BE619835A (fr) Dérivés de la thiamine et leur préparation
BE604111A (fr) Dérivés éthyléniques et leur préparation.
BE602887A (fr) Nouveaux dérivés de 8-benzylxanthines et leur préparation.
BE600673A (fr) Dérivés de phénylalanine et leur préparation
BE613226A (fr) Dérivés de la 1.2.4-benzothiadiazine et leur préparation
BE603114A (fr) Nouveaux dérivés des dialkylxanthines et leur préparation
FR1388605A (fr) Dérivés de sérine et leur préparation
FR1294115A (fr) Dérivés du thiaxanthène et leur préparation
BE602326A (fr) Dérivés du thiophénicol et leur préparation
FR1300734A (fr) Phényl-thiopurines et leur préparation
BE607685A (fr) Préparation de 1,2-diphényl-4-carbamoyl-3,5 pyrazolidinedione.
BE617967A (fr) Dérivés de dicycloheptènes et leur préparation