BE536469A - - Google Patents
Info
- Publication number
- BE536469A BE536469A BE536469DA BE536469A BE 536469 A BE536469 A BE 536469A BE 536469D A BE536469D A BE 536469DA BE 536469 A BE536469 A BE 536469A
- Authority
- BE
- Belgium
- Prior art keywords
- heparin
- solution
- salt
- previously
- pyrogens
- Prior art date
Links
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical class OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims description 14
- 238000000034 method Methods 0.000 claims description 10
- 230000001698 pyrogenic effect Effects 0.000 claims description 4
- 239000000126 substance Substances 0.000 claims description 3
- 239000002244 precipitate Substances 0.000 claims description 2
- 239000000243 solution Substances 0.000 claims 8
- 229960002897 heparin Drugs 0.000 claims 4
- 229920000669 heparin Polymers 0.000 claims 4
- 239000002510 pyrogen Substances 0.000 claims 3
- 159000000000 sodium salts Chemical class 0.000 claims 3
- 230000000694 effects Effects 0.000 claims 2
- 239000000706 filtrate Substances 0.000 claims 2
- QTWJRLJHJPIABL-UHFFFAOYSA-N 2-methylphenol;3-methylphenol;4-methylphenol Chemical compound CC1=CC=C(O)C=C1.CC1=CC=CC(O)=C1.CC1=CC=CC=C1O QTWJRLJHJPIABL-UHFFFAOYSA-N 0.000 claims 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 230000002378 acidificating effect Effects 0.000 claims 1
- 229910052783 alkali metal Inorganic materials 0.000 claims 1
- -1 alkali metal salt Chemical class 0.000 claims 1
- 229940127090 anticoagulant agent Drugs 0.000 claims 1
- 239000003146 anticoagulant agent Substances 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 229920002678 cellulose Polymers 0.000 claims 1
- 239000001913 cellulose Substances 0.000 claims 1
- 239000003610 charcoal Substances 0.000 claims 1
- 230000002566 clonic effect Effects 0.000 claims 1
- 229930003836 cresol Natural products 0.000 claims 1
- 239000012153 distilled water Substances 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 238000001914 filtration Methods 0.000 claims 1
- 239000012535 impurity Substances 0.000 claims 1
- 238000012423 maintenance Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 230000002035 prolonged effect Effects 0.000 claims 1
- 238000000926 separation method Methods 0.000 claims 1
- 239000006228 supernatant Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE536469A true BE536469A (d) |
Family
ID=167150
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE536469D BE536469A (d) |
Country Status (1)
| Country | Link |
|---|---|
| BE (1) | BE536469A (d) |
-
0
- BE BE536469D patent/BE536469A/fr unknown
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