BE393156A - - Google Patents

Info

Publication number

BE393156A

BE393156A BE393156DA BE393156A BE 393156 A BE393156 A BE 393156A BE 393156D A BE393156D A BE 393156DA BE 393156 A BE393156 A BE 393156A

Authority

BE

Belgium

Prior art keywords

calcium

acids

water

salts

calcium salts

Prior art date

Links

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• 239000002253 acid Substances 0.000 claims description 19
• 150000007513 acids Chemical class 0.000 claims description 18
• 159000000007 calcium salts Chemical class 0.000 claims description 14
• 239000011664 nicotinic acid Substances 0.000 claims description 8
• 238000000034 method Methods 0.000 claims description 6
• 239000007864 aqueous solution Substances 0.000 claims description 4
• AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 claims description 2
• 239000000920 calcium hydroxide Substances 0.000 claims description 2
• 229910001861 calcium hydroxide Inorganic materials 0.000 claims description 2
• BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 1
• 239000007900 aqueous suspension Substances 0.000 claims 1
• XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 15
• 239000000243 solution Substances 0.000 description 12
• 150000003839 salts Chemical class 0.000 description 9
• OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 8
• 229960005069 calcium Drugs 0.000 description 8
• 229910052791 calcium Inorganic materials 0.000 description 8
• 239000011575 calcium Substances 0.000 description 8
• VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 6
• 239000004227 calcium gluconate Substances 0.000 description 6
• 229960004494 calcium gluconate Drugs 0.000 description 6
• 235000013927 calcium gluconate Nutrition 0.000 description 6
• NEEHYRZPVYRGPP-UHFFFAOYSA-L calcium;2,3,4,5,6-pentahydroxyhexanoate Chemical compound [Ca+2].OCC(O)C(O)C(O)C(O)C([O-])=O.OCC(O)C(O)C(O)C(O)C([O-])=O NEEHYRZPVYRGPP-UHFFFAOYSA-L 0.000 description 6
• 239000000047 product Substances 0.000 description 6
• 239000002970 Calcium lactobionate Substances 0.000 description 4
• RGHNJXZEOKUKBD-SQOUGZDYSA-N D-gluconic acid Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O RGHNJXZEOKUKBD-SQOUGZDYSA-N 0.000 description 4
• 229940050954 calcium lactobionate Drugs 0.000 description 4
• 235000019307 calcium lactobionate Nutrition 0.000 description 4
• UOQHWNPVNXSDDO-UHFFFAOYSA-N 3-bromoimidazo[1,2-a]pyridine-6-carbonitrile Chemical compound C1=CC(C#N)=CN2C(Br)=CN=C21 UOQHWNPVNXSDDO-UHFFFAOYSA-N 0.000 description 3
• LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
• RHEMCSSAABKPLI-SQCCMBKESA-L calcium;(2r,3r,4r,5r)-2,3,5,6-tetrahydroxy-4-[(2s,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanoate Chemical compound [Ca+2].[O-]C(=O)[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O.[O-]C(=O)[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O RHEMCSSAABKPLI-SQCCMBKESA-L 0.000 description 3
• 235000012208 gluconic acid Nutrition 0.000 description 3
• 229940099563 lactobionic acid Drugs 0.000 description 3
• 239000000203 mixture Substances 0.000 description 3
• 239000000843 powder Substances 0.000 description 3
• 239000002244 precipitate Substances 0.000 description 3
• RGHNJXZEOKUKBD-UHFFFAOYSA-N D-gluconic acid Natural products OCC(O)C(O)C(O)C(O)C(O)=O RGHNJXZEOKUKBD-UHFFFAOYSA-N 0.000 description 2
• 238000001704 evaporation Methods 0.000 description 2
• 230000008020 evaporation Effects 0.000 description 2
• 229930182830 galactose Natural products 0.000 description 2
• 239000000174 gluconic acid Substances 0.000 description 2
• JYTUSYBCFIZPBE-AMTLMPIISA-N lactobionic acid Chemical compound OC(=O)[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O JYTUSYBCFIZPBE-AMTLMPIISA-N 0.000 description 2
• 239000003960 organic solvent Substances 0.000 description 2
• RGHNJXZEOKUKBD-MBMOQRBOSA-N D-mannonic acid Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)C(O)=O RGHNJXZEOKUKBD-MBMOQRBOSA-N 0.000 description 1
• WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
• JYTUSYBCFIZPBE-UHFFFAOYSA-N Maltobionic acid Natural products OC(=O)C(O)C(O)C(C(O)CO)OC1OC(CO)C(O)C(O)C1O JYTUSYBCFIZPBE-UHFFFAOYSA-N 0.000 description 1
• WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 description 1
• 239000012736 aqueous medium Substances 0.000 description 1
• 230000015572 biosynthetic process Effects 0.000 description 1
• JYTUSYBCFIZPBE-ZNLUKOTNSA-N cellobionic acid Chemical compound OC(=O)[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O JYTUSYBCFIZPBE-ZNLUKOTNSA-N 0.000 description 1
• 238000001816 cooling Methods 0.000 description 1
• 150000002016 disaccharides Chemical class 0.000 description 1
• 239000008103 glucose Substances 0.000 description 1
• 238000010438 heat treatment Methods 0.000 description 1
• 238000004519 manufacturing process Methods 0.000 description 1
• 238000002360 preparation method Methods 0.000 description 1
• 239000007858 starting material Substances 0.000 description 1
• 239000000725 suspension Substances 0.000 description 1
• 238000002560 therapeutic procedure Methods 0.000 description 1