BE2015C005I2 - - Google Patents

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Publication number
BE2015C005I2
BE2015C005I2 BE2015C005C BE2015C005C BE2015C005I2 BE 2015C005 I2 BE2015C005 I2 BE 2015C005I2 BE 2015C005 C BE2015C005 C BE 2015C005C BE 2015C005 C BE2015C005 C BE 2015C005C BE 2015C005 I2 BE2015C005 I2 BE 2015C005I2
Authority
BE
Belgium
Application number
BE2015C005C
Other languages
French (fr)
Original Assignee
Univ Pittsburgh Commonwealth Sys Higher Education
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/388,173 external-priority patent/US7270800B2/en
Priority claimed from US10/645,847 external-priority patent/US20050043523A1/en
Application filed by Univ Pittsburgh Commonwealth Sys Higher Education filed Critical Univ Pittsburgh Commonwealth Sys Higher Education
Publication of BE2015C005I2 publication Critical patent/BE2015C005I2/fr

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/64Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • C07D277/66Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2 with aromatic rings or ring systems directly attached in position 2
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/60Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
BE2015C005C 2003-03-14 2015-01-27 BE2015C005I2 (US07576130-20090818-C00114.png)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/388,173 US7270800B2 (en) 2000-08-24 2003-03-14 Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition
US10/645,847 US20050043523A1 (en) 2003-08-22 2003-08-22 Benzothiazole derivative compounds, compositions and uses

Publications (1)

Publication Number Publication Date
BE2015C005I2 true BE2015C005I2 (US07576130-20090818-C00114.png) 2023-03-07

Family

ID=35057877

Family Applications (1)

Application Number Title Priority Date Filing Date
BE2015C005C BE2015C005I2 (US07576130-20090818-C00114.png) 2003-03-14 2015-01-27

Country Status (16)

Country Link
EP (1) EP1611115B1 (US07576130-20090818-C00114.png)
JP (1) JP4875487B2 (US07576130-20090818-C00114.png)
CN (2) CN102532055B (US07576130-20090818-C00114.png)
AU (2) AU2004221897B2 (US07576130-20090818-C00114.png)
BE (1) BE2015C005I2 (US07576130-20090818-C00114.png)
BR (1) BRPI0408274B8 (US07576130-20090818-C00114.png)
CY (2) CY1113334T1 (US07576130-20090818-C00114.png)
DK (1) DK1611115T3 (US07576130-20090818-C00114.png)
ES (1) ES2393921T3 (US07576130-20090818-C00114.png)
HK (1) HK1086270A1 (US07576130-20090818-C00114.png)
HU (1) HUS1500006I1 (US07576130-20090818-C00114.png)
NO (3) NO330861B1 (US07576130-20090818-C00114.png)
PL (1) PL1611115T3 (US07576130-20090818-C00114.png)
PT (1) PT1611115E (US07576130-20090818-C00114.png)
RU (1) RU2440995C2 (US07576130-20090818-C00114.png)
SI (1) SI1611115T1 (US07576130-20090818-C00114.png)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5022554B2 (ja) * 2000-08-24 2012-09-12 ユニバーシティ オブ ピッツバーグ オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション アルツハイマー病の生前診断ならびにアミロイド沈着物のインビボ画像化および予防に用いるためのチオフラビン誘導体
US7270800B2 (en) 2000-08-24 2007-09-18 University Of Pittsburgh Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition
US20050261365A1 (en) * 2004-05-20 2005-11-24 The Scripps Research Institute Transthyretin stabilization
GB0516564D0 (en) * 2005-08-12 2005-09-21 Ge Healthcare Ltd Fluorination process
ES2414614T3 (es) * 2007-01-30 2013-07-22 Ge Healthcare Limited Herramientas para ayudar en el diagnóstico de enfermedades neurodegenerativas
CN101293878B (zh) * 2007-04-25 2010-12-15 中国科学院上海应用物理研究所 苯并噻唑苯胺类化合物及其制备方法和应用
EP2323697A2 (en) * 2008-07-24 2011-05-25 Siemens Medical Solutions USA, Inc. Imaging agents useful for identifying ad pathology
US8895313B2 (en) * 2008-09-23 2014-11-25 Wista Laboratories Ltd. Ligands for aggregated tau molecules
CA2920068A1 (en) * 2013-09-26 2015-04-02 F. Hoffmann-La Roche Ag Imidazo[1,2-a]pyridin-7-amines as imaging tools
JP6260967B2 (ja) * 2013-11-06 2018-01-17 国立大学法人京都大学 放射性ヨウ素標識化合物、及び、これを含む放射性医薬
CN103613589B (zh) * 2013-11-29 2016-03-30 江苏华益科技有限公司 一种用于神经退行性疾病领域的新型pet显像剂前体及标准品的合成方法
JP2017528520A (ja) * 2014-08-29 2017-09-28 シーエイチディーアイ ファウンデーション,インコーポレーテッド ハンチントンタンパク質のイメージング用プローブ
CN109400615B (zh) * 2017-08-18 2021-07-16 上海交通大学医学院附属新华医院 一种靶向β-淀粉样蛋白的香豆素类化合物及其制备与应用
GR1009516B (el) * 2018-03-22 2019-05-02 Εκεφε Δημοκριτος Τρικαρβονυλο-συμπλοκα μεταλλων μεταπτωσεως με βενζο-ετεροκυκλικο παραγωγο του κυκλοπενταδιενυλικου ανιοντος με υψηλη διαπερατοτητα του αιματοεγκεφαλικου φραγμου για εφαρμογες στη διαγνωση και θεραπεια νοσων του κνς

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ID22275A (id) * 1996-11-22 1999-09-23 Elan Pharm Inc Komposisi farmasi yang terdiri dari derivat asam amino n-(aril atau heteroaril) dan metode untuk menghambat pelepasan b-amiloid peptida dan atau sintesisnya dengan menggunakan senyawa tersebut
GB9919673D0 (en) * 1999-08-20 1999-10-20 Cancer Res Campaign Tech 2-Arlybenzazole compounds
JP5022554B2 (ja) * 2000-08-24 2012-09-12 ユニバーシティ オブ ピッツバーグ オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション アルツハイマー病の生前診断ならびにアミロイド沈着物のインビボ画像化および予防に用いるためのチオフラビン誘導体
EP1345914A1 (en) * 2000-12-22 2003-09-24 AstraZeneca AB Therapeutic compounds
US6696039B2 (en) * 2001-04-23 2004-02-24 Trustees Of The University Of Pennsylvania Amyloid plaque aggregation inhibitors and diagnostic imaging agents
GB0229686D0 (en) * 2002-12-20 2003-01-29 Amersham Plc Solid-phase fluorination of benzothiazoles

Also Published As

Publication number Publication date
JP4875487B2 (ja) 2012-02-15
EP1611115A1 (en) 2006-01-04
CN102532055B (zh) 2016-05-11
AU2011200667B2 (en) 2011-12-22
AU2004221897A2 (en) 2004-09-30
CN102532055A (zh) 2012-07-04
DK1611115T3 (da) 2012-11-26
NO20054674L (no) 2005-12-13
AU2004221897A1 (en) 2004-09-30
BRPI0408274A (pt) 2006-03-21
HUS1500006I1 (hu) 2015-02-18
NO2015005I1 (no) 2015-03-02
BRPI0408274B1 (pt) 2019-02-26
SI1611115T1 (sl) 2012-12-31
EP1611115B1 (en) 2012-08-22
AU2011200667A1 (en) 2011-03-10
CN1784392A (zh) 2006-06-07
NO20054674D0 (no) 2005-10-11
ES2393921T3 (es) 2013-01-02
AU2004221897A9 (en) 2009-08-20
PT1611115E (pt) 2012-12-07
NO20110980L (no) 2005-12-13
RU2005131872A (ru) 2006-02-27
NO2015005I2 (no) 2015-02-18
PL1611115T3 (pl) 2013-01-31
RU2440995C2 (ru) 2012-01-27
HK1086270A1 (en) 2006-09-15
AU2004221897B2 (en) 2010-11-18
NO330861B1 (no) 2011-08-01
BRPI0408274B8 (pt) 2021-05-25
JP2006522104A (ja) 2006-09-28
CY1113334T1 (el) 2015-12-09
CY2015007I1 (el) 2015-12-09

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