BE1026968B1 - Phytotherapeutic and / or nutritherapeutic composition comprising at least one plant extract and / or at least one nutrient - Google Patents

Abstract

The present invention relates to a phytotherapeutic and / or nutritherapeutic composition comprising at least one plant extract and / or at least one nutrient, said composition further comprising at least one excipient other than magnesium stearate and / or silicon dioxide and / or silicon dioxide and / or at least one nutrient. or titanium dioxide.

Description

+ BE2019 / 5404 Phytotherapeutic and / or nutritherapeutic composition comprising at least one plant extract and / or at least one nutrient The present invention relates to a phytotherapeutic and / or nutritherapeutic composition comprising at least one plant extract and / or at least one nutrient.

Herbal medicine is based on the use and administration of plant extracts and natural active ingredients to heal while nutritherapy (or orthomolecular medicine) is based on the use and administration of nutrients such as mineral salts, trace elements, vitamins, amino acids and fatty acids, to overcome organic imbalances.

The compositions of phytotherapeutic andor nutritherapeutic types conventionally comprise at least one excipient in order to confer a given consistency, or other particular physical or taste characteristics, to the final product, while avoiding any interaction, particularly chemical, with the active principle. In general, excipients are substances which promote the uptake of a composition (for example a food supplement) but which have no real therapeutic functions.

Numerous phytotherapeutic and / or nutritherapeutic compositions comprising at least one plant extract and / or at least one nutrient are known. However, in current phytotherapeutic and / or nutritherapeutic compositions, the active substances - that is to say the plant extracts, the natural active principles and the nutrients - are systematically combined with at least one of the following excipients in the form of nanoparticles: magnesium stearate and / or silicon dioxide and / or titanium dioxide.

However, recent studies show that these nanoparticles are potentially harmful to human health. For example, the ingestion of nanoparticles of titanium dioxide or silicon dioxide by rats would cause immune disorders and precancerous lesions. This is also why these excipients are gradually starting to be banned or at least strongly discouraged.

As can be seen, phytotherapy and nutritherapy being by definition therapies based on the use of natural and healthy substances, "the use of such nanoparticles as excipients is not tolerable and is even incompatible. There is therefore a real need for to date to provide phytotherapeutic and / or nutritherapeutic compositions which are totally healthy and not harmful to public health.

To this end, according to the invention and to solve at least in part these problems of the state of the art, a phytotherapeutic and / or nutritherapeutic composition is provided comprising at least one plant extract and / or at least one nutrient, said composition further comprising at least one excipient other than magnesium stearate and / or silicon dioxide and / or titanium dioxide.

Preferably, according to the invention, said at least one excipient other than magnesium stearate and / or silicon dioxide and / or titanium dioxide is chosen from the group consisting of lithothamne and / or an extract of lithothamne, of spirulina and / or an extract of spirulina and moringa and / or an extract of moringa and mixtures thereof.

By the terms "plant extract", it is understood, within the meaning of the present invention, a constituent initially present in a plant and which is extracted therefrom. In particular, to obtain this plant extract, a so-called plant extraction (“plant extraction”) is carried out. This is a solid / liquid separation operation: a solid body (the plant) is brought into contact with a fluid (the solvent). The plant compounds of interest are then solubilized and contained in the solvent. The solution thus obtained is the desired extract. The solvent will then be optionally removed in order to isolate the plant extract. If it is food, it is not mandatory to separate it from the extract. Otherwise, a second separation operation makes it possible to obtain a dry extract. In other words, plant extraction is a solid / liquid extraction, possibly followed by purification steps. It is therefore defined as an operation of separation of one or more constituents (solid or liquid) contained in a solid body (plant or part of plant) by dissolving in a fluid. This fluid, generally called a solvent, can be a liquid or a gas (water vapor or supercritical fluids).

Plant extracts make it possible to present, in an easily usable form, the active ingredients of plants, flowers, bark, roots or even any other exploitable part of a plant. In order to obtain these extracts and therefore to extract the active agents from the plants, the solvents conventionally used are water, propylene glycol, butylene glycol, glycerin, alcohol. Other solvents can be used and the choice of a particular solvent will be made according to the active ingredients sought and according to the desire to favor or eliminate a particular support. Nowadays, the extraction of plant active ingredients uses precise machines and benefits from considerable advances in process engineering, phytochemistry and analytical chemistry.

Note that a distinction is made between so-called standardized extracts, which essentially guarantee the quality of products comprising these extracts. Standardized plant extracts contain a specific amount of active ingredients, knowing that the amount of active ingredients in a plant can vary considerably depending on the variety of plant, the part of the plant used (root, leaf, flower, …) And the climatological conditions, the season and the soil in which the plant was grown. That is why the plants are first carefully determined and checked before being harvested. After extraction in order to dissolve the active principles and after possible evaporation of the solvent (water or alcohol), the concentrated extract is standardized: the standard content of active principle is checked. Standardized extracts guarantee a constant quality of the finished product, contain a higher concentration of active ingredients thanks to the elimination of superfluous materials (non-active substances), keep better since superfluous materials (eliminated) can no longer harm the principles active and have better bioavailability. Therefore, according to a preferred embodiment according to the present invention, the plant extract used in a composition according to the invention is a standardized plant extract.

By the term “nutrient”, it is understood, within the meaning of the present invention, a food substance which can be directly assimilated. Nutrients, or nutrients, are made up in the body by all the organic and inorganic compounds necessary for the living organism to sustain life. Nutrients are elementary components contained in food, or from the surrounding nature.

They are used by the body to ensure the maintenance, the metabolic and physiological functioning of an individual, in particular his development and his growth.

Lithothamne (Lithotamum calcareum) is a red marine algae of the coral family whose thallus (vegetative apparatus without root, without stem or leaf) contains particularly high levels of calcium, sodium, iodine, sulfur, iron , boron magnesium, copper, cobalt, nickel, selenium, zinc, silver.

It is therefore in itself a very effective food supplement which, combined with minerals or vitamins, provides an undeniable advantage.

In addition, the pH of lithothamne is particularly alkaline, which allows it to compensate for the acidity of the body.

The ability of lithothamne to eliminate tissue acidification meets the needs of the entire population and the inflammatory conditions that accompany it (osteoarthritis, cancer, colitis or stress-related diseases). It is also recognized that lithothamne does not foul the body unlike, for example, magnesium stearate which overloads the liver, disrupts intestinal assimilation and causes renal precipitation.

Spirulina is a bacterial food obtained from cyanobacteria of the genus Arthrospira and used as a food supplement but also as food.

Spirulina contains essential elements for human health including on average 60% of vegetable proteins, vitamins (A, E, D, B1, B2, B3, B6, B8, K), beta-carotene, minerals and trace elements (calcium, phosphorus, magnesium, iron, zinc, copper, manganese, chromium, sodium, potassium and selenium). Spirulina is also rich in chlorophyll and phycocyanin and contains enzymes, the most important of which is superoxide dismutase (SOD) which contains iron.

Finally, this cyanobacterium contains essential fatty acids: omega 6, gamma-linolenic acid.

Moringa (Moringa oleifera) is a tree with interesting nutritional properties since these leaves contain many minerals (calcium, potassium, magnesium, phosphorus, iron, zinc, etc.), many vitamins (B, E, C, etc.), many essential amino acids

> BE2019 / 5404 (leucine, valine, lysine, ...), fatty acids (palmitic, linoleic, oleic, ...) and several antioxidants (glutathione, quercetin, flavonoids, ...).

In the context of the present invention, it has been determined that the use of an excipient other than magnesium stearate and / or silicon dioxide and / or titanium dioxide, in particular that the use of a excipient chosen from the group consisting of lithothamne and / or an extract of lithothamne, spirulina and / or an extract of spirulina and moringa and / or an extract of moringa and mixtures thereof, makes it possible to substitute effectively and advantageously the conventional excipients of magnesium stearate, silicon dioxide and titanium dioxide types. In fact, it has been shown that the final products obtained according to the invention have physical characteristics that are entirely appropriate and equivalent to those obtained with the excipients used to date.

In addition, a considerable advantage is that the excipients according to the invention inherently exhibit phytotherapeutic and / or nutritherapeutic properties, these properties further reinforcing the healthy and non-harmful nature of the compositions according to the invention. In addition, it has been established that the various active substances used in a composition according to the invention exhibit high bioavailability.

Finally, it has also been demonstrated that an excipient according to the invention, in particular an excipient chosen from the group consisting of lithothamne and / or an extract of lithothamne, spirulina and / or a spirulina and moringa extract and / or a moringa extract and their mixtures, makes it possible to potentiate the action / increase the effect of the active substances used (plant extracts, natural active principles and nutrients) .

By the term “bioavailability”, it is necessary to understand within the meaning of the present invention, a pharmacokinetic property, namely the fraction of a dose which reaches the bloodstream in unchanged form. Bioavailability is therefore a measure of the rate of absorption and of the quantity of active principle absorbed.

Advantageously, according to the invention, said at least one plant extract is a plant extract obtained from a plant chosen from the group consisting of Prunus armeniaca, Artemisia absinthium, Robinia pseudoacacia, Leucaena

© BE2019 / 5404 glauca, Anacardium occidental, Acalypha indica, Acanthus mollis, Malpighia punicifolia, Levisticum officinale, Apium graveolens, Achillea millefolium, Achillea moschata, Achillea nana, Achillea ptarmica, Aconitum ferox, Aconitum napumpellus, Aconitum napumpellus.

Vulparia, Acorus calamus aromaticus, Actaea racemosa, Cimicifuga racemosa, Actinomyces albus, Actinomyces griseus, Adonis vernalis, Agaricus laricis, Agaricus campester, Agave rigida, Leonurus cardiaca, Agrostis alba, Agrostis vulgaris, Allinum ursivator, Allinum ursivator, Allinum ursivator , Allium victorialis, Ailanthus glandulosa, Vaccinium myrtillus, Vaccinium vitis-idaea, Alchemilla alpina, Alchemilla vulgaris, Aletris farinosa, Medicago sativa, Physalis alkekengi, Alliaria officinalis, Aloe vera, Aloe ferox, Amygdalus communis, Amanita citrina, Amanita phallosa, Amanita bulboides , Amanita muscaria, Amanita rubescens, Amaranthus spinosus, Amaryllis equestris, Hibiscus abelmoschus, Ambrosia artemisiifolia, Ammi visnaga, Semecarpus anacardium, Anacardium occidentalis, Ananassa comosus, Ananassa sativa, Aquilegia vulgareum, Pydendatilla vulgaris, Ananassa sativa, Aquilegia vulgareum, Arborosa vulgaris, Ananassa sativa, Aquilegia vulrumone, Arborosa vulgaris, Ananassa sativa, Ananassa vulgareum, Anubemilla vulgaris, Ananassa vulgaris, Ananassa vulgaris, Anubemilla vulgaris, Anubemilla vulgaris, Anissatilla vulgaris, Anissatilla vulgarisone ranunculoides, Anethum graveolens, Angelica archangelica, Angelic a pyrenaea, Angelica anomala, Angelica sinensis radix, Angelica sylvestris, Angustura vera, Cusparia febrifuga, Galipea cusparia, Galipea febrifuga, Galipea officinalis, Illicium anisatum, Illicium verum, Pimpinella anisum, Anthyllicus racedo, Aryllicis unennensis, Arabisbutalia anisum, Aryllicus racedo, Vulnerus racemosus, Arbutus andrachne, Rhus cotinus, Myrica cerifera, Cercis siliquastrum, Chionanthus virginica, Argemone mexicana, Hippophae rhamnoides, Aristolochia clematitis, Aristolochia infesta, Aristolochia rotunda, Artemisia vulgaris, Artemisia seguinum, Aristolium, Aristolochia seguinum, Cynadium, Cynadium Diefenbachia seguine, Arum maculatum, Arum vulgare, Asarum europaeum, Asarum officinale, Asarum canadense, Asclepias tuberosa, Ferula assa-foetida, Scorodosma foetidum, Asimina triloba, Annona triloba, Jonesia odoca, Asparagus officoranchoratum, Asperula odoca, Asparagus officinanchica, Asperium odoca, Asparagus officinanchoratum, Galperium odoca, Asparagus officoranchoranta, Galperium odoca, Asparagus officinanchoratum, Galperium odoca, Asparagus officoranchoranchica Asphodelus albus, Hura crepitans, Hura brasiliensis, Aster acris, Astragalus gummifer, Astragalus exscapus, Athamanta cretensis, Crataegus oxyacantha, Crataegus laevigata, Crataegus monogyna, Solanum melongena, Alburnum tiliae, Aucuba japonica, Alnus incana, Alnusglutinosa, Alnus abromatus, Lauria sativa, Avena sativa, Inemisia persiva, Inula persia, Persia persea Persea gratissima, Avena sativa, Avena elatior, Illicium anisatum, Illicium verum, Ballota nigra, Bambousa arundinacea, Arctium lappa, Commiphora molmol, Ocimum basilicum, Atropa belladonna, Styrax tonkinensis, Geum urbanum, Heradetonys officinalis officinalis, Stachetonys officinalis officinalis, Stachetonys officinalis officinalis, , Citrus aurantium, Polygonum bistorta, Triticum sativum, Centaurea cyanus, Quillaya, Peumus boldus, Pimpinella saxifraga, Verbascum thapsus, Betula pendula, Frangula alnus, Rhamnus frangula, Borago officinalis, Erica Cinerea, Onchonia spinosa vulgaris, Brychonia spinosa vulgaris, Onchonia deusgarosa, , Arctostaphylos uva-ursi, Coffea arabica, Cannabis, Chamaemelum nobile, Matricaria recut ita, Cinnamomum verum, Daucus carota, Ceratonia siliqua, Carum carvi, Cascara sagrada, Rhammus purshianus, Ribes nigrum, Centaurium erythraea, Prunus cerasus, Cnicus benedictus, Silybum marianum, Chelidonium majus, Quercus robumens, Eichorium repensia, Eritopyrium Chrysanthellum americanum, Citrus aurantium, Colchicum autumnale, Marsdenia cundurango, Symphytum officinale, Papaver rhoeas, Curcubita pepo, Curcuma longa, Cupressus sempervirens, Datura stramonium, Digitalis lanata, Digitalis purpurea, Echinacea purpurosus, Rosa canocciltaherea, Echinacea purpurosus, Rosa canocciltaherica, sentchlorica Elifornia , Eucalyptus globulus, Eupatorium cannabinum, Anethum graveolens, Foeniculum vulgare, Trigonella foenium-graecum, Semecarpus anacardium, Ficus carica, Ruscus aculeatus, Fragaria vesca, Rubus ldaeus, Fraxinus excelsior, Avena elaticolinus officumminia, Garcia vescinaria, Fucumminia officumminia, Avena elaticolus officumminia, Garcia -gutta, Galeopsis segetum, Juniperus communis, Gentiana lute a, Lathyrus linifolius, Zingiber officinalis, Ginkgo biloba, Panax ginseng, Panax quinquefolius, Syzygium aromaticum, Inula helenium, Chamaemelum nobile, Symphytum officinale, Ambrosia artemisiifolia, Malva sylvestris, Paulliniaana, Commipeaiscinum album, officuliana cupuliana, virginia mukuliana, Phaesolus vulgaris, Harpagophytum procumbens, Alliaria officinalis, Ammi visnaga, Hypericum perforatum, Humulus lupulus, Hyssopus officinalis, Helichrysum arenarium, Cephaëlis Ipécacuanha, Plantago ovata, Pilocarpus pennatifolius, Hyoscyamia nitjacumus niger, Hyoscyamus albumus niger, Hyoscyamus, Pennatifolida, Amculhallaamus, Pennatifolida, Lamculipera, Pennatifolida, Lamculipera, Pennatifolida, Lamculipera, Pena, Hyssopus, , Laurusnobilis, Lavandula angustifolia, Saccharomyces cerevisiae, Cetraria islandica, Hedera helix, Glechoma hederacea, Linum usitatissimum, Lithothamnium calcareum, Levisticum officinale, Medicago sativa, Zea mays, Aesculus hippocastanum, Marrubium Parixidita vulgutarians, Larix paragidis, Matricidis sylutris, Lizcidaria , Melilotus albus, Mel ilotus officinalis, Melissa officinalis, Mentha piperita, Menyanthes trifoliata, Hypericum perforatum, Verbascum densiflorum, Brassica nigra, Commiphora molmol, Vaccinium myrtillus, Opuntia ficus-indica, Olea europaea, Oenothera bienhonist, Orthos aurantium, Lamaminiphonist, Lamaminiphonium arterios, Lamaminiphonium arantium artery Urtica urens, Urtica dioica, Acalypha indica, Citrus decumana, Carica papaya, Tanacetum parthenium, Passiflora incarnata, Papaver somniferum, Viola tricolor, Vinca minor, Petasites hybridus, Pimpinella saxifraga, Ruscus aculeatus, Matriceaia ennella recutitaio diaaurica, Matriceaia, Pilella recutitaio, Centacaurica , Pinus mugo, Pinus sylvestris, Taraxacum, Plantago major, Plantago ovata, Plantago lanceolata, Plantago afra, Podophyllum peltatum, Polyga senega, Potentilla anserina, Potentilla argentea, Potentilla erecta, Portulaca oleracea, Equisetum, Equisetum veris, Prunus spinosa, Primula Cinchona officinalis, Cinchona pubescens, Raphanus sativus, Vitis sp, Ephedra sini ca, Arctostaphylos uva-ursi, Krameria lappacea, Rauvolfia vomitoria, Glycyrrhiza glabra, Filipendula ulmaria, Polygonum bistorta, Polygonum aviculare, Rheum palmatum, Ricinus communis, Rosmarinus officinalis, Rubus fruticosus.

Drosera rotundifolia, Serenoa repens, Smilax medica, Saponaria officinalis, Satureja hortensis, Salvia lavandulifolia, Salvia officinalis, Salvia tribola, Salix alba, Urginea maritima, Cassia angustifolia, Cassia senna, Thymus serpyllum, Soja, Calendula maxima, Calendulina officinalis, Spirulina stellium Sambucus nigra, Tanacetum parthenium, Camellia sinensis, Thymus vulgaris, Tilia sylvestris, Tilia platyphyllos, Myroxylon balsamum, Menyanthes trifoliata, Tussilago farfara, Valeriana officinalis, Solidago virgaurea, Erigeron canadensis, Veronoyanga odoranga, Verboyanga officinata, Veronoyanga officinata, Cana officinanga , Zingiber officinalis.

This list is not exhaustive and, according to the invention, it is preferentially planned to use plant extracts which are accepted by national laws and treaties in the context of the manufacture of phytotherapeutic and / or nutritherapy compositions.

? BE2019 / 5404 Preferably, according to the invention, said at least one nutrient is chosen from the group consisting of mineral salts, trace elements, vitamins, amino acids and fatty acids, and mixtures thereof.

Preferably, the composition according to the invention is in the form of a capsule, a tablet, a capsule, a lozenge, a soluble powder, or in a liquid or viscous or oily packaged form or not in a container, for example in an ampoule.

Advantageously, the composition according to the invention is in the form of a food supplement.

Preferably, the various components of a composition according to the invention are components of biological origin, preferably 100% biological and whose traceability is recognized.

The present invention also relates to a use of a composition according to the invention in the preventive and / or curative treatment of pathologies relating to the lymphatic system, the circulatory system, the cardiovascular system, the cutaneous system, the digestive system, the respiratory system, bone and joint system and immune system.

A use of a composition according to the invention can also take place in the following fields of application: female well-being, male well-being, premature aging, the immune system (preventive and curative), the circulatory system (back venous and lymphatic,…), the cardiovascular system in the broad sense (tension - heart rate - coronary circulation, cholesterol - diabetes,…), the respiratory system, stress and its consequences, sleep disorders, the cutaneous system, the digestive system, the bone system, the articular system, detoxification and energy and vitality.

The present invention also relates to a kit comprising: a first container comprising a composition according to the invention; and - a second container comprising a composition in the form of a concentrated macerate comprising glycerin, water, alcohol and at least one extract of a growing plant embryonic tissue, said alcohol being an alcohol of which the alcoholic strength expressed as a volume percentage is less than or equal to 25% vol. and said composition comprising at least one extract of a plant embryonic tissue in

LO BE2019 / 5404 growth at a rate of at least 5% (v / v), preferably at a rate of at least 10% (v / v), preferably at a rate of at least 12% (v / v).

According to the invention, the second container comprises a macerate such as those produced in the context of phytembryotherapy based on the use of embryonic tissues of trees or plants, for example on the use of buds, embryological tissues, young shoots, rootlets, or even young leaves. More specifically, phytembryotherapy is based on the use of a macerate obtained via a process using water, alcohol and glycerin without taking place a subsequent step of dilution of the macerate: we speak of of "mother macerate" highly concentrated in active ingredients. Phytembryotherapy therefore recommends the use of growing plant embryonic tissues macerated in a water-glycerin-alcohol mixture to obtain a concentrated glycerin macerate (mother macerate).

Water plays a role in the extraction of active ingredients such as water-soluble derivatives, tannins, mineral salts, water-soluble flavonoids, water-soluble vitamins and water-soluble acids. Alcohol also plays a role in the extraction of active ingredients such as alkaloids, heterosides, glycosides and certain acids. Glycerin, for example vegetable glycerin extracted from rapeseed, is also involved in the extraction of active ingredients such as phenols, fat-soluble flavonoids and fat-soluble vitamins.

The embryonic tissues of plants and in particular the buds of plants contain all the biological and energy potential of the future plant (only one of these embryonic cells can, in vitro, reconstitute the plant in its entirety) and all the genetic information. It is a concentrate of active ingredients that can, for example, in the case of buds, regulate metabolic functions and / or potentiate the therapeutic effects of nutritherapy and phytotherapy.

Preferably, according to the invention, said glycerin is a natural vegetable glycerin, for example a natural vegetable glycerin obtained from rapeseed.

Advantageously, according to the invention, said alcohol is ethanol, in particular bio-ethanol obtained from wheat.

H BE2019 / 5404 Preferably, according to the invention, said at least one extract of a growing plant embryonic tissue is chosen from the group consisting of extracts derived from buds, embryological tissues, young shoots, rootlets, young leaves. and their mixtures.

Preferably, according to the invention, said at least one extract of a growing plant embryonic tissue is an extract of a plant chosen from the group consisting of Vaccinium vitis idaea, Amygdala dulcis, Cercis siliquastrum, Crataegus oxyacantha, Alnus glutinosa, Betula alba, Betula verrucosa, Calluna vulgaris, Ribes nigrum, Cedrus libani, Carpinus betulus, Castanea vesca, Quercus robur, Lonicera japonica, Citrus limon, Cornus sanguinea, Acer campestris, Ficus carica, Rubus idaeus, Fraxinus excelsior, Juniperus bilis , Viscum album, Fagus Sylvatica, Syringa vulgaris, Zea mays, Aesculus hippocastanum, Larix decidua, Morus Nigra, Vaccinium myrtillus, Corylus avellana, Juglans regia, Olea europaea, Ulmus campestri, Populus nigra, Pinus montalisana, Malmarus orientanus officinalis, Rubus fructicosus, Rosa canina, Abies pectinata, Salix Alba, Secale cereale, Sequoia gigantea, Sorbus aucuparia L, Tamaris gallica, Tilia tomentosa, Vitis vinifera , Ampelopsis weitchii, Viburnum lantana and their mixtures.

Advantageously, said at least one extract of a growing plant embryonic tissue is a fresh extract, not cryoground and / or not refrigerated and / or not dehydrated.

The present invention has been described in relation to specific embodiments, which have a purely illustrative value and should not be considered as limiting. In general, it will be obvious to those skilled in the art that the present invention is not limited to the examples illustrated and / or described above.

The use of the verbs "to understand", "to include", "to include", or any other variant, as well as their conjugations, can in no way exclude the presence of elements other than those mentioned.

The use of the indefinite article "a", "a", or of the definite article "the", "the" OR "l" ", to introduce an element does not exclude the presence of a plurality of these elements.

Claims (8)

Claims 1. Phytotherapeutic and / or nutritherapeutic composition comprising at least one plant extract and / or at least one nutrient, said composition further comprising at least one excipient other than magnesium stearate and / or silicon dioxide and / or carbon dioxide. titanium. 2. Composition according to claim 1, characterized in that said at least one excipient other than magnesium stearate and / or silicon dioxide and / or titanium dioxide is chosen from the group consisting of lithothamne and / or of an extract of lithothamne, spirulina and / or an extract of spirulina and moringa and / or an extract of moringa and mixtures thereof. 3. Composition according to claim 1 or 2, characterized in that said at least one plant extract is a plant extract derived from a plant chosen from the group consisting of Prunus armeniaca, Artemisia absinthium, Robinia pseudoacacia, Leucaena glauca, Anacardium occidental, Acalypha indica, Acanthus mollis, Malpighia punicifolia, Levisticum officinale, Apium graveolens, Achillea millefolium, Achillea moschata, Achillea nana, Achillea ptarmica, Aconitum ferox, Aconitum napellus, Aconitum lycoctonum subsp. Vulparia, Acorus calamus aromaticus, Actaea racemosa, Cimicifuga racemosa, Actinomyces albus, Actinomyces griseus, Adonis vernalis, Agaricus laricis, Agaricus campester, Agave rigida, Leonurus cardiaca, Agrostis alba, Agrostis vulgaris, Allinum ursivator, Allinum ursivator, Allinum ursivator , Allium victorialis, Ailanthus glandulosa, Vaccinium myrtillus, Vaccinium vitis-idaea, Alchemilla alpina, Alchemilla vulgaris, Aletris farinosa, Medicago sativa, Physalis alkekengi, Alliaria officinalis, Aloe vera, Aloe ferox, Amygdalus communis, Amanita citrina, Amanita phallosa, Amanita bulboides , Amanita muscaria, Amanita rubescens, Amaranthus spinosus, Amaryllis equestris, Hibiscus abelmoschus, Ambrosia artemisiifolia, Ammi visnaga, Semecarpus anacardium, Anacardium occidental, Ananassa comosus, Ananassa sativa, Aquilegia vulgaris, Ananassa sativa, Aquilegia vulgareum, Arborosa vulgaris, Ananassa sativa, Aquilegiaemonrumenemorides, Pydendulatilla anculaunilla, Anculatilla anculilla, Ananculia, Ananculilla, Ananculia, Anancula, Anancula, Ananculilla, Ananassone, Anacardia, Ananassaemonona, Anacardium, Anacardium, Anacardium anacardilla, Aquilegiaemonrumen , Anethum graveolens, Angelica archangelica, Angelica pyrenaea, Angelica anomala, Angelica sinensis radix, Angelica sylvestris, Angustura vera, Cusparia febrifuga, Galipea cusparia, Galipea febrifuga, Galipea officinalis, Illicium anisatum, Illicium verum, Pimpinella anisum, Anthyllis vulneraria, Arabis cebennensis, Aralia racemosa, Arbutus unedo, Symphoricarpus racemosus, Arbutus andrachne, Rhus cotinus, Myrica cerifera, Cercis siliquastrum, Chionanthus virginica, Argemone mexicana, Hippophae rhamnoides, Aristolochia clematitis, Aristolochia infesta, Aristolochia rotunda, Artemisia vulgaris, Artemisiaselengensis, Arnica montana, Cynaraguinum sebum, Aradium sebachiaguinum, Diefenbachiabachium, Aradium sebachiabachium, Aradium sebachiabachium Arum vulgare, Asarum europaeum, Asarum officinale, Asarum canadense, Asclepias tuberosa, Ferula assa-foetida, Scorodosma foetidum, Asimina triloba, Annona triloba, Jonesia asoca, Asparagus officinalis, Asperula odoranta, Galium odoratum, Asperula cynanchica, Asphodelus albus, Hura crepitans, Hura brasiliensis, Aster acris, Astragalus gummifer, Astragalus exscapus, Athamanta cretensis, Crataegus oxyacantha, Crataegus laevigata, Crataegus monogyna, Solanum melonutia, Alincanus glonutia, Alincanus glonutia, Alincana, Alincana, Alincana, Alincana, Alincana, Alincana japnus, Alincana, Alincana, Alincana, Alincana japnus Inula helenium, Artemisia abromatum, Avena sativa, Laurus persea, Persea americana, Persea gratissima, Avena sativa, Avena elatior, Illicium anisatum, Illicium verum, Ballota nigra, Bambousa arundinacea, Arctium lappa, Commiphora molmol, Ocimum basileum, Atropa belladonna, Styrax tonkinum, urbaneum , Stachys officinalis, Stachys officinalis, Betonicaofficinalis, Citrus aurantium, Polygonum bistorta, Triticum sativum, Centaurea cyanus, Quillaya, Peumus boldus, Pimpinella saxifraga, Verbascum thapsus, Betula pendula, Frangula alnus, Rhamnus Borago officinalis, Erica Cinerea, Calluna vulgaris, Bryonia dioica, Anchusa officinalis, Ononis spinosa, Arctostaphylos uva-ursi, Coffea arabica, Cannabis, Chamaemelum nobile, Matricaria recutita, Cinnamomum verum, Daucus carota, Ceratonia siliqua, Carum carvi, Cascara sagrada, Rhammus purshianus, Ribes nigrum, Centaurium erythraea, Prunus cerasus, Cnicus benedictus, Silyercidonium robonium majurum, Quelercidonium robonium majurum, Cichorium intybus, Aropyrum repens, Elytrigia repens, Chrysanthellum americanum, Citrus aurantium, Colchicum autumnale, Marsdenia cundurango, Symphytum officinale, Papaver rhoeas, Curcubita pepo, Curcuma longa, Cupressus sempervirens, Datura strameapurinapurina, Digalislanalis purina, Rosa caninacea, Digalislanacea Eleutherococcus senticosus, Epilobium parviflorum, Eschscholtzia californica, Eucalyptus globulus, Eupatorium cannabinum, Anethum graveolens, Foeniculum vulgare, Trigonella foenium-graecum, Semecarpus anacardium, Ficus carica, Ruscus rubaria aculeatus, Idaus aculeatus, Fraxinus excelsior, Avena elatior, Fucus vesicolusus, Fumaria officinalis, Alpinia officinarum, Garcinia gummi-gutta, Galeopsis segetum, Juniperus communis, Gentiana lutea, Lathyrus linifolius, Zingiber officinalis, Ginkgobiloba, Panzaxquinum gutta, Syfolygemomatic gutta, nobile, Symphytum officinale, Ambrosiaartemisiifolia, Malva sylvestris, Paullinia cupana, Commiphora mukul, Viscum album, Althaea officinalis, Hamamelis virginiana, Phaesolus vulgaris, Harpagophytum procumbens, Alliaria officinalis, Ammi visnaga, Hypericulrysopichelarium, Helrysopichus officinus, Helrysopichus, Helrysopichus, Helrysopichus, Helrysopichus, Helrysopichus, Helrysopichus, Helrysopichus, Helrysopichus, Ipécacuanha, Plantago ovata, Pilocarpus pennatifolius, Hyoscyamus niger, Sterculia urens, Piper methysticum, Cola nitida, Amorphophallus konjac, Lamium album, Laurus nobilis, Lavandula angustifolia, Saccharomyces cerevisiae, Cetraria islandica, Hedera helix, Glechoma hederacea, Linum usitatissimum, Lithotaysumium officiva, Miumaysium sativa , Aesculus hippocastanum, Marrubium vulgare, Ilex Paraguariensis, Matricaria recutita, Malva sylvestris, Larix decidua, Melilotus albus, Melilotus officinalis, Melissa officinalis, Mentha piperita, Menyanthes trifoliata, Hypericum perforatum, Verbascum densiflorum, Brassica nigra, Commiphora molmol, Vaccinium myrtillus, Opuntia ficus-indica, Olea europaea, Oenothera biennis, Citrus aurantium, Orthosiphon aristatus, Orthosiphon stamineus, Lamium album, Urtica urens, Urtica dioica, Acalypha indica, Citrus decumana, Carica papaya, Tanacetum parthenium, Passiflora incarnata, Papaver somniferum, Viola tricolor, Vincaminor, Petasites acaciaecutita, Pimulagaaurium, Rususcariuscita, Centaruscita, Rususcita sax erythraea, Antennaria dioica, Hieracium pilosella, Pinus mugo, Pinus sylvestris, Taraxacum, Plantago major, Plantago ovata, Plantago lanceolata, Plantago afra, Podophyllum peltatum, Polyga senega, Potentilla anserina, Potentilla argentea, Potentilla erectumerecta, Equisetilla olea, Potentilla erectumerecta, Equisetilla olea , Primula veris, Prunus spinosa, Cinchona officinalis, Cinchona pubescens, Raphanus sativus, Vitis sp, Ephedra sinica, Arctostaphylos uva-ursi, Krameria lappacea, Rauvolfia vomitoria, Glycyrrhiza glabra, Filipendula ulmarum, Polygonum bicarpideum, Polygoneum birchortum, Polygoneum, Polygoneum, Polygorta ulmarum , Rosmarinus officinalis, Rubus fruticosus. Drosera rotundifolia, Serenoa repens, Smilax medica, Saponaria officinalis, Satureja hortensis, Salvia lavandulifolia, Salvia officinalis, Salvia tribola, Salix alba, Urginea maritima, Cassia angustifolia, Cassia senna, Thymus serpyllum, Soja, Calendula maxima, Calendulina officinalis, Spirulina stellium Sambucus nigra, Tanacetum parthenium, Camellia sinensis, Thymus vulgaris, Tilia sylvestris, Tilia platyphyllos, Myroxylon balsamum, Menyanthes trifoliata, Tussilago farfara, Valeriana officinalis, Solidago virgaurea, Erigeron canadensis, Veronoyanga odoranga, Verboyanga officinata, Veronoyanga officinata, Cana officinanga , Zingiber officinalis. 4. Composition according to any one of the preceding claims, characterized in that said at least one nutrient is chosen from the group consisting of mineral salts, trace elements, vitamins, amino acids and fatty acids, and mixtures thereof. 5. Composition according to any one of the preceding claims, characterized in that it is in the form of a capsule, a tablet, a capsule, a lozenge, a soluble powder, or in a liquid or viscous or oily form packaged or not in a container, for example in an ampoule. 6. Composition according to any one of the preceding claims, characterized in that it is in the form of a food supplement. 7. Composition according to any one of the preceding claims for use in the preventive and / or curative treatment of pathologies relating to the lymphatic system, to the circulatory system, to the cardiovascular system, to the cutaneous system, to the digestive system, to the respiratory system. , the bone and joint system and the immune system. 8. Kit comprising: - A first container comprising a composition according to any one of claims 1 to 7; and - a second container comprising a composition in the form of a concentrated macerate comprising glycerin, water, alcohol and at least one extract of a growing plant embryonic tissue, said alcohol being an alcohol of which the alcoholic strength expressed as a volume percentage is less than or equal to 25% vol. and said composition comprising at least one extract of a growing plant embryonic tissue at a rate of at least 5% (v / v), preferably at a rate of at least 10% (v / v), preferably at a rate of d 'at least 12% (v / v).