BE1022417B1 - COMPOSITIONS COMPRISING ACTIVE INGREDIENTS OF AT LEAST ONE PLANT - Google Patents

Abstract

The present invention relates to compositions in gel form, which can be used externally, comprising active ingredients of at least one plant. These compositions are formed: a) of a quantity of active ingredients of at least one plant, either in the form of a suspension of particles of at least one fresh plant or in the form of a hydrosol, of a hydrolate reconstituted, of a mixture of hydrosols, reconstituted or not or of a wine either in the form of a mixture on the one hand of a suspension of particles of at least one fresh plant and on the other hand of a hydrosol , of a reconstituted hydrosol, of a mixture of hydrosols, whether or not reconstituted, or of a wine, and: b) a maximum quantity of 10% by weight of at least one cold gelling agent.

Description

COMPOSITIONS COMPRISING ACTIVE INGREDIENTS FROM MQINS2012 / C

A PLANT

The present invention generally relates to compositions comprising active ingredients of at least one plant, as well as to their method of preparation and their use.

More particularly, the invention relates to compositions, in gel form, useful in the pharmaceutical, cosmetic or hygienic field.

For millennia, man has sought to soothe his ills, to ensure his hygiene or to heal and beautify his skin with plants. To date, many pharmaceutical, cosmetic or hygienic compositions exist and contain plants in the form of dry plants or fresh crushed plants.

Compositions of this type, which can be used externally, have been disclosed, for example in: Patent Application FR 2,591,891, which describes compositions, in a pasty galenic form based on fresh crushed plants, which may comprise % to 75% of plants, 1% to 5% of a gelling agent, 0.15% to 0.5% preservatives and 5% to 30% glycerol. patent application FR 2 622 453, which relates compositions, in gel form, based on fresh plants in the form of grains or particles obtained by grinding. According to one embodiment, this gel contains from 0.5% to 20% (w / v) of plants and from 0.3% to 21% (w / v) of a gelling agent and one or more vehicles. and at least one adjuvant. the patent application FR 2,660,312, which describes stabilized pasty compositions which may comprise at least 50% of fresh plant (s) with a particle size of a few microns to a few millimeters, at least 8% to 45% of a degradation reaction blocking solvent and at least 10% of a desiccant and / or sequestering agent, the patent application FR 2,677,885, which relates compositions comprising a transparent support comprising a gel and an emulsion, that solid elements, in the form of grains or particles, obtained by grinding fresh plants suspended in this support.These solid elements are coated with a protective layer.These compositions may contain from 0.05% I to 20% by weight of plants, from 0.1% to 21% by weight of a gelling agent, from 5% to 50% by weight of a surfactant and a vehicle of the active element of the plant. Patent FR 2,770,400, which relates to cosmetic compositions or ermopharmaceuticals containing from 0.5% to 50% by weight of hydrosol or floral water of shea flower. This hydrosol can be combined with gelling and viscosity polymers. Other compositions comprising active ingredients of at least one plant have been reported in: a) "Gelees" from Wendy Stephen: "Das Grosse

Buch der Desserts ", 1999, Könemann Verlagsgesellschaft mbh, Köln where jellies containing fresh plant particles, a gelling agent and transformation products of a fresh plant, namely a wine and sugar are described, b) the demand for Patent FR 1 493 942 which describes fruit juice concentrate containing fruit juice in the form of concentrate or fresh juice, a gelling agent and transformation products of a fresh plant, in this case sugar, c ) Patent Application FR 1 412 406 which discloses the preparation of gelled fruit juice comprising fresh plant particles (fruit juice), a gelling agent and a transformation product of a fresh plant 012 / - in the sugar occurrence, d) the patent application WO 2008/012424 which describes the production of a food product in gelled form formed of a mixture containing a first type of ingredient selected from vegetables, fruits, gold juice plant origin and their derivatives, a second type of ingredient namely a cold gelling agent and a third type of ingredient namely a hot gelling agent, e) the patent application GB 389 500 which describes a process for the preparation of suspensions of liquid-insoluble substances, such as fruit syrups, containing a fruit juice, a gelling agent, a transformation product of a fresh plant (sugar) and citric acid, f) the patent application FR No. 2,752,770 which reports hair washing compositions containing plant extracts, a hydrophilic crosslinked acrylic acid polymer as well as concentrates of algae, menthol essence or camphor, preservatives and emulsifiers, g) patent application CA 2,378,890 which relates the preparation of a spread, made from cane sugar, comprising sugar cane juice, gelling agents, a preservative and a neutraceutical, h) the patent application CN 102 784 080 which describes a washing solution for the hands comprising natural extracts of plants as well as other ingredients such as xanthan gum, stearin, methyl glucoside sesquistearate, glycerin and gasoline.

The many ingredients, which generally fall into all these known compositions, prevent them from being strongly concentrated in the form of a fresh plant (s). On the other hand, these additional ingredients may be contraindicated to some users, because of, for example, potentially allergenic properties.

The object of the present invention is to provide compositions in the form of a gel capable of overcoming these disadvantages in that they may contain an extremely large concentration of fresh plants in the form of particles and a minimum of components in addition to the fresh plant or plants. in question.

In fact, it has surprisingly been found that the product resulting from the reduction of one or more fresh plants in the form of particles suspended in a liquid, hereinafter also referred to as "vegetable fluid", is capable, when a very small quantity of a cold gelling agent is brought into contact with it, thereby gelling itself, thus giving rise to a completely gel-like composition.

Accordingly, the invention relates to compositions of the type reported above, characterized in that they contain only: a) a quantity of active ingredients of at least one plant, either in the form of a suspension of particles at least one fresh plant is in the form of a transformation product of at least one fresh plant, in this case a hydrolate, a reconstituted hydrolate or a wine, or in the form of a mixture of on the one hand a suspension of particles of at least one fresh plant and secondly a hydrolate, a reconstituted hydrosol, a mixture of reconstituted or non-reconstituted hydrolates or a wine, and: b) a maximum quantity 10% by weight of at least one cold gelling agent.

In the context of the present description and the claims, unless otherwise indicated, "% by weight" means a percentage by weight of the total composition formed by the combination of active ingredients of at least 20% by weight. a plant and at least one cold gelling agent.

As mentioned previously, active ingredients of at least one fresh plant may come from a transformation product of at least one fresh plant. It is in fact a product obtained after physical or chemical treatments of at least one fresh plant, in this case a product resulting from a vinification process, namely a wine, or a distillation of the plant namely a hydrosol. It may also be a reconstituted hydrosol, for example from essential oil, or a mixture of hydrolats reconstituted or not.

The plants used in the compositions of the invention are useful plants in particular in cosmetology and for skin care. It will be, more generally, any plant, plant extract or part of plant containing active ingredients and / or nutritive for the skin. Any plant or plant part meeting this criterion may be used in particular, fruits, roots, flowers or leaves depending on the species. By way of examples, the fresh plants as well as the product originating from the transformation of fresh plants, listed below, can be used in compositions for external use according to the invention, especially in cosmetic compositions:

Cucumber: softens the skin.

Carrot: refines the grain of the skin and softens the epidermis.

Apple: produces a gentle skin exfoliating effect, nourishes, revitalizes and protects the skin.

Nettle: regulates the secretion of sebum and cleanses the skin.

Tomato: brightens the complexion, cleans the skin and relieves irritation. 2012/0

Ginger: cleanses and beautifies the skin; Raspberry antifungal: purifies, refreshes and gives radiance to the skin.

Cherry: Tones the skin, softens and revitalizes the skin.

Beetroot: moisturizes, soothes irritations.

Melon: softens, moisturizes, nourishes the skin.

Cabbage: disinfects, heals, tones.

Chamomile: calm, softens the skin; anti-inflammatory.

Wine: stimulates micro-circulation, tightens pores and protects the skin. On the other hand, the compositions of the invention may comprise mixtures of plants, for example a mixture of cucumber and raspberry.

According to a preferred embodiment, the active ingredients of at least one plant, whether in the form of a suspension of fresh plant particles or in the form of a hydrolate or a reconstituted hydrosol or wine, are present in the compositions of the invention at greater than 76% and up to 99.99% by weight of this composition independently of any additional ingredient that may be added thereto.

Usually, the suspension concentration of fresh plant particles or of hydrolate, reconstituted hydrolate or wine is greater than 90%, in particular greater than 95% and preferably about 98%. The gelling agent used in the compositions according to the invention is a natural or synthetic hydrophilic cold gelling agent. By "cold gelling agent" is meant a gelling agent whose temperature reduction initiates the gelling effect of this agent in contrast to the hot gelling agent whose temperature rise initiates the gelation of this agent. . This cold gelling agent may be chosen from individual products or families of products comprising: galactomannans, cellulose and its derivatives, gelatin, silicas, alginates, pectins, palmitostearates, laurates, myristates and carbomers . Preferably, the cold gelling agent is xanthan gum, guar gum, gelatin and, in particular, a carbomer, for example carbomer 980.

In addition, according to a preferred embodiment, the cold gelling agent is usually present in the composition at a maximum of 5, 3, 2, 1% by weight or less than 1% by weight of the composition. For example, a carbomer may be used at less than 1% by weight of the composition and, depending on the case, at 0.1% by weight.

In an altogether incidental manner, the compositions of the invention may also contain, if necessary, additional ingredients such as antibacterial or anti-fermenting components, such as for example EDTA, in order to ensure better preservation of these substances. or agents capable of improving certain aspects of these compositions such as tromethamol, sodium lauryl sulphate, propylene glycol or glycerol. The dermal application of a plant fluid or a transformation product of fresh plant (s), for example a wine, used as such, that is to say without any additional physical or chemical modification, n provides only a low level of transdermal penetration of the active ingredients in this plant fluid or product. Generally, the desired effect on the skin, after application of the plant fluid in question or the product in question, tends to appear only slightly and after 012/0 a fairly prolonged period of time, that is to say the order of 1 to 2 hours or more, given the small amount of active agents able to pass the skin barrier to reach the recipient cell.

Tests carried out with compositions according to the invention, comprising a vegetable fluid or a transformation product of fresh plant (s) in this case a hydrolate, a reconstituted hydrosol or a wine, have shown that it is It is possible to absorb, through the skin, the quasi-total quantity of the active agents present in this plant fluid or this transformation product of fresh plant (s), the desired effect on the skin may already appear a few minutes later. application.

According to another of its objects, the invention relates to a process for the preparation of the compositions according to the invention, according to which a suspension of active ingredients of at least one plant is mixed with the necessary amount of gelling agent. in a cold state and at a temperature ranging from 5 ° C. to 100 ° C., depending on the gelling agent or mixture of gelling agents chosen, and optionally additional ingredients are then added.

When the plant particles are in the form of fresh plant particles, they are obtained for example by centrifugation of the fresh plant (s) in question or by grinding thereof, optionally followed by a sieving the ground. These operations thus provide a plant fluid formed of fresh plant particles (s) suspended in a liquid.

However, when the plant particles are in the form of a fresh plant transformation product (s), the product in question, which is a wine, a hydrolate or a hydrolate, is used as it was € 2012/0 prepared or obtained, in known manner, without further modification or transformation.

The compositions according to the invention are preferably in the form of compositions that can be used externally. These can be applied in the context of well-being care or in cosmetology or dermatology in order to preserve the skin from any deterioration and to promote the maintenance and rejuvenation.

The following nonlimiting examples illustrate compositions according to the invention in gel form for external use as well as their method of preparation. EXAMPLE 1

COSMETIC COMPOSITION BASED ON CUCUMBER

A composition for external use of the following formulation is produced:% by weight of the composition

Vegetable Fluid (Cucumber Fluid) 97.9

Carbomer 2.1 100.0

Cucumber is centrifuged in an ultra fine manner to obtain a liquid containing particles of this vegetable in suspension. 97.9 g of this vegetable fluid are then taken and at room temperature 2.1 g of carbomer are added. It ends by mechanically whisking the mixture for 35 min at room temperature. EXAMPLES 2 TO 5

In the same manner as before but adding, if necessary, additional ingredients, compositions having the following formulations were prepared:

Vegetable fluid (carrot fluid) 95 to 98%

Xanthan gum 2 to 5%

Vegetable fluid (raspberry fluid) 90 to 99%

Guar gum 1 to 10%

Vegetable fluid (ginger fluid) 95 to 99.7%

Carbomer 0.1 to 5%

Tromethamol 0.1 to 5% EDTA 0.1 to 1% EXAMPLES 7 and 8

The desired amount of guar gum or gelatin powder is melted and the required amount of vegetable fluid obtained by grinding and then sieving is added to separate the fibrous elements therefrom. The mixture is immediately whipped for at least 30 minutes and cooled rapidly thereafter.

In this way, the following compositions were prepared:

Vegetable fluid (nettle fluid) 90 to 95%

Guar gum 5 to 10%

Vegetable fluid (beet fluid) 90 to 98%

Gelatin powder 2 to 10%

Claims (17)

CLAIMS 2012/0 ( 1. Gel compositions, usable externally, comprising active ingredients of at least one plant, characterized in that they contain only: a) an amount of active ingredients of at least one plant, either under form of a suspension of particles of at least one fresh plant either in the form of a hydrolate, a reconstituted hydrolate, a mixture of reconstituted or non-reconstituted hydrolates or a wine or in the form of a mixture on the one hand, a suspension of particles of at least one fresh plant and, on the other hand, a hydrolate, a reconstituted hydrolate, a mixture of reconstituted or non-reconstituted hydrolates or a wine, and b) a maximum amount of 10% by weight of at least one cold gelling agent. 2. Compositions according to claim 1, characterized in that they comprise active ingredients of at least one plant in the form of a suspension of particles of at least one fresh plant. 3. Compositions according to claim 1, characterized in that they comprise active ingredients of at least one plant in the form of a hydrolate, a reconstituted hydrosol or a mixture of reconstituted hydrolates. 3. Compositions according to claim 1, characterized in that they comprise active ingredients of at least one plant in the form of a wine. 4. Compositions according to claim 1 or 2, characterized in that the fresh plants are selected from cucumber, carrot, apple, nettle, tomato, ginger, raspberry beetroot, melon, cabbage, chamomile. 5. Compositions according to claim 1 or 3, characterized in that the hydrolates or reconstituted hydrolates are selected from those from cucumber, carrot, apple, nettle, tomato, ginger, raspberry, cherry, beetroot, melon, cabbage, chamomile. 6. Compositions according to one of claims 1 to 5, characterized in that the gelling agent is present in a maximum of 5, 3, 2, 1% by weight or less than 1% by weight of the composition. 7. Compositions according to one of claims 1 to 6, characterized in that the cold gelling agent is present in a maximum of 2% by weight of the composition. 8. Compositions according to one of claims 1 to 7, characterized in that the cold gelling agent is present in a maximum of 1% by weight of the composition. 9. Compositions according to one of claims 1 to 8, characterized in that the cold gelling agent is a natural or synthetic hydrophilic gelling agent chosen from individual products or families of products comprising galactomannans, cellulose and its derivatives, gelatin, silicas, alginates, pectins, palmitostearates, laurates, myristates and carbomers. 10. Compositions according to one of claims 1 to 8, characterized in that the cold gelling agent is xanthan gum, guar gum, gelatin or a carbomer. 2012 / Οί 11. Compositions according to one of claims 1 to 9, characterized in that the cold gelling agent is a carbomer used in a proportion of less than 1% by weight of the composition. 12. Compositions according to one of claims 1 to 11, characterized in that the concentration of active ingredients of at least one plant is greater than 90% independently of any additional antibacterial or anti-fermenting agent that may be added thereto. Compositions according to claim 12, characterized in that the concentration of active ingredients of at least one plant is greater than 95%. 14. Compositions according to claim 12 or 13, characterized in that the concentration of active ingredients of at least one plant is close to 98%. 15. Compositions according to one of claims 1 to 11, characterized in that they contain, in addition, antibacterial agents or anti-fermenting agents. 25 16. Compositions according to one of claims 1 to 11, characterized in that they are used in cosmetology or dermatology. 17. Process for the preparation of compositions according to one of claims 1 to 12, characterized in that the active ingredients of at least one plant are mixed with the necessary amount of cold gelling agent and this, at a temperature ranging from 5 ° C to 100 ° C depending on the gelling agent or mixture of gelling agents selected, then anti-fermentative antibacterial agents 012 / 0i are optionally added.