BE1002890A3 - ANTIVIRAL AND IMMUNOSTIMULANT PHARMACEUTICAL COMPOSITIONS AND PROCESS FOR PREPARING THE SAME. - Google Patents

ANTIVIRAL AND IMMUNOSTIMULANT PHARMACEUTICAL COMPOSITIONS AND PROCESS FOR PREPARING THE SAME. Download PDF

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Publication number
BE1002890A3
BE1002890A3 BE8900254A BE8900254A BE1002890A3 BE 1002890 A3 BE1002890 A3 BE 1002890A3 BE 8900254 A BE8900254 A BE 8900254A BE 8900254 A BE8900254 A BE 8900254A BE 1002890 A3 BE1002890 A3 BE 1002890A3
Authority
BE
Belgium
Prior art keywords
pharmaceutical compositions
antiviral
immunostimulant
preparing
same
Prior art date
Application number
BE8900254A
Other languages
French (fr)
Inventor
Nagy Peter Literati
Maria Boros
Jeno Szilbereky
Istvan Racz
Gyoengyver Soos
Miklos Koller
Alan Pinter
Gabor Nemeth
Original Assignee
Biorex Kft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biorex Kft filed Critical Biorex Kft
Application granted granted Critical
Publication of BE1002890A3 publication Critical patent/BE1002890A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Abstract

La présente invention concerne de nouvelles compositions pharmaceutiques antivirales et/ou immunostimulantes, qui comprennent comme composants actifs . des aminoacides apparaissant dans des organismes vivants et/ou leurs dérivés dans lesquels le groupe carboxy est substitué par un groupe alkyle en C1-4 ou un groupe amino ou par un cation métal alcalin, métal alcalino-terreux ou ammonium ou les hydrates et/ou sels de ces composés, avec un ou plusieurs acides gras en C18-24 contenant un groupe alkyle portant au moins deux doubles liaisons, éventuellement en mélange avec des supports et/ou des additifs et des antioxydants utilisés couramment dans l'industrie pharmaceutique, dans lesquelles le rapport molaire de l'aminoacide et du ou des acides gras est de 1:4 à 4:1. L'invention est de plus relative à un procédé pour la préparation de ces compositions.The present invention relates to novel antiviral and / or immunostimulatory pharmaceutical compositions, which comprise as active components. amino acids appearing in living organisms and / or their derivatives in which the carboxy group is substituted by a C1-4 alkyl group or an amino group or by an alkali metal, alkaline earth metal or ammonium cation or hydrates and / or salts of these compounds, with one or more C18-24 fatty acids containing an alkyl group carrying at least two double bonds, optionally in admixture with carriers and / or additives and antioxidants commonly used in the pharmaceutical industry, in which the molar ratio of amino acid and fatty acid (s) is 1: 4 to 4: 1. The invention further relates to a process for the preparation of these compositions.

BE8900254A 1988-03-09 1989-03-09 ANTIVIRAL AND IMMUNOSTIMULANT PHARMACEUTICAL COMPOSITIONS AND PROCESS FOR PREPARING THE SAME. BE1002890A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU881132A HU209973B (en) 1988-03-09 1988-03-09 Process for production of antiviral and immunstimular pharmaceutical composition

Publications (1)

Publication Number Publication Date
BE1002890A3 true BE1002890A3 (en) 1991-07-16

Family

ID=10952974

Family Applications (1)

Application Number Title Priority Date Filing Date
BE8900254A BE1002890A3 (en) 1988-03-09 1989-03-09 ANTIVIRAL AND IMMUNOSTIMULANT PHARMACEUTICAL COMPOSITIONS AND PROCESS FOR PREPARING THE SAME.

Country Status (14)

Country Link
JP (1) JPH01316316A (en)
KR (1) KR890014103A (en)
BE (1) BE1002890A3 (en)
CA (1) CA1334576C (en)
CH (1) CH678918A5 (en)
DE (1) DE3907649C2 (en)
FI (1) FI94591C (en)
FR (1) FR2628324B1 (en)
GB (1) GB2216418B (en)
HU (1) HU209973B (en)
IT (1) IT1229562B (en)
LU (1) LU87471A1 (en)
NL (1) NL8900574A (en)
SE (1) SE8900828L (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU210122B (en) * 1988-03-23 1995-02-28 Biorex Kutato Fejlesztoe Kft Process for production of composition against thromboembolytic conditions of circulating system and heart
JPH04279523A (en) * 1991-01-11 1992-10-05 Nisshin Flour Milling Co Ltd Fatty oil processed product for stimulating immunity
GB9304746D0 (en) * 1993-03-09 1993-04-28 Scotia Holdings Plc Treatment of viral infections
WO1994022438A1 (en) * 1993-03-26 1994-10-13 Constantin Romulus Dinu Pharmaceutical composition for the treatment of certain viruses and autoimmune diseases and the procedure of its preparation
GB9318611D0 (en) * 1993-09-08 1993-10-27 Sandoz Nutrition Ltd Improvements in or relating to organic compounds
US5767156A (en) * 1993-10-06 1998-06-16 Peptide Technology Limited Polyunsaturated fatty acids and uses thereof
IT1264987B1 (en) * 1993-12-14 1996-10-17 Prospa Bv SALTS OF A POLYUNSATURATED FATTY ACID AND PHARMACEUTICAL FORMULATIONS THAT CONTAIN THEM
AUPM906594A0 (en) * 1994-10-26 1994-11-17 Peptide Technology Limited Synthetic polyunsaturated fatty acid analogues
DE19503993A1 (en) * 1995-02-08 1996-08-14 Johann Friedrich Dr Med Desaga Enteral product contg n-3-fatty acid or deriv and medium chain length tri:glyceride
US5639858A (en) * 1995-03-22 1997-06-17 Tularik, Inc. Human signal transducer and binding assays
AU5002196A (en) * 1995-03-28 1996-10-16 Novo Nordisk A/S Immunosuppressive agents
HU227588B1 (en) * 2004-12-03 2011-09-28 Sinnex Mueszaki Fejlesztoe Es Tanacsado Kft Antiviral and immunostimulant pharmaceutical composition containing polyunsaturated fatty acid esters
CN101939000A (en) * 2007-12-17 2011-01-05 佛罗里达大学研究基金会有限公司 Be used for the treatment of outgrowth material of pathologic ocular angiogenesis and method
FR3031451B1 (en) * 2015-01-13 2018-03-23 Greentech SALT OF TRIGLYCERIDE, PREPARATION AND USES
EP3248467A1 (en) 2016-05-25 2017-11-29 Evonik Technochemie GmbH Method for preparing a composition containing omega-3-fatty acid-l-lysin-salts
WO2017202942A1 (en) * 2016-05-25 2017-11-30 Evonik Technochemie Gmbh Tablets with high active ingredient content of omega-3 fatty acid amino acid salts
WO2019008101A1 (en) 2017-07-06 2019-01-10 Evonik Technochemie Gmbh Enteric coated solid dosage form comprising omega-3 fatty acid amino acid salts
AU2018317802B2 (en) 2017-08-15 2024-04-04 Evonik Operations Gmbh Tablets with high active ingredient content of omega-3 fatty acid amino acid salts
BR112022002129A2 (en) 2019-08-08 2022-04-19 Evonik Operations Gmbh Downstream process for the production of polyunsaturated fatty acid salts
US20220287345A1 (en) 2019-08-08 2022-09-15 Evonik Operations Gmbh Solubility enhancement of poorly soluble actives
DE102022003441A1 (en) 2022-09-17 2024-03-28 Jutta Ibrahim Omega3 and essential amino acid supplements

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0069659A1 (en) * 1981-07-03 1983-01-12 CHANY, Charles Medicine containing the reaction product of a carboxylic acid and a basic amino acid
US4513008A (en) * 1982-07-30 1985-04-23 The Vinoxen Company, Inc. Virucidal compositions and therapy
DE3726299A1 (en) * 1987-06-26 1989-02-23 Dietl Hans Fat emulsion for intravenous use

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GB1256162A (en) * 1968-08-16 1971-12-08 Braun Fa B Improvements in and relating to liquid products for intravenous administration
FR2215212B1 (en) * 1973-01-18 1976-03-05 Seperic Ch
GB2118437B (en) * 1982-03-01 1984-12-12 Efamol Ltd Composition for treating alcoholism
DE3229956A1 (en) * 1982-08-12 1984-02-16 Erichsen, Friedrich Karl, Dr., 2351 Schillsdorf Pharmaceutical compositions with cytostatic action
DE3514328C1 (en) * 1985-04-19 1986-09-11 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts, 6900 Heidelberg Use of L-ornithine in the selective inhibition of cytotoxic T-lymphocyte effector cells
DE3785667T2 (en) * 1986-09-17 1994-07-21 Clintec Nutrition Co ADDITIONAL FOOD OR THERAPY FOR PERSONS WITH RISK OR TREATMENT FOR ARTERIOSCLEROTIC VASCULAR, CARDIOVASCULAR AND / OR THROMBOTIC DISEASES.
AU1489688A (en) * 1987-02-20 1988-09-14 Shriners Hospitals For Crippled Children Omega-3 fatty acids in traumatic injury treatment

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0069659A1 (en) * 1981-07-03 1983-01-12 CHANY, Charles Medicine containing the reaction product of a carboxylic acid and a basic amino acid
US4513008A (en) * 1982-07-30 1985-04-23 The Vinoxen Company, Inc. Virucidal compositions and therapy
DE3726299A1 (en) * 1987-06-26 1989-02-23 Dietl Hans Fat emulsion for intravenous use

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
UNLISTED DRUGS, vol. 39, no. 7, juillet 1987 (CHATHAM, New jersey, U.S.A.) *

Also Published As

Publication number Publication date
HUT60432A (en) 1992-09-28
JPH01316316A (en) 1989-12-21
FI891145A0 (en) 1989-03-09
CA1334576C (en) 1995-02-28
FI94591B (en) 1995-06-30
LU87471A1 (en) 1990-10-02
IT8919704A0 (en) 1989-03-09
SE8900828L (en) 1989-09-10
CH678918A5 (en) 1991-11-29
IT1229562B (en) 1991-09-04
DE3907649A1 (en) 1989-09-28
SE8900828D0 (en) 1989-03-09
KR890014103A (en) 1989-10-21
GB2216418B (en) 1991-12-11
FR2628324B1 (en) 1994-05-27
HU209973B (en) 1995-01-30
GB8905385D0 (en) 1989-04-19
GB2216418A (en) 1989-10-11
FI94591C (en) 1995-10-10
NL8900574A (en) 1989-10-02
FR2628324A1 (en) 1989-09-15
DE3907649C2 (en) 1996-07-11
FI891145A (en) 1989-09-10

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: BIOREX KFT

Effective date: 19970331