AU9298198A - Di-n-heterocyclic compounds, methods, and compositions for inhibiting parp activity - Google Patents

Di-n-heterocyclic compounds, methods, and compositions for inhibiting parp activity

Info

Publication number
AU9298198A
AU9298198A AU92981/98A AU9298198A AU9298198A AU 9298198 A AU9298198 A AU 9298198A AU 92981/98 A AU92981/98 A AU 92981/98A AU 9298198 A AU9298198 A AU 9298198A AU 9298198 A AU9298198 A AU 9298198A
Authority
AU
Australia
Prior art keywords
compositions
methods
heterocyclic compounds
parp activity
inhibiting parp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU92981/98A
Other languages
English (en)
Inventor
Paul F. Jackson
Keith M. Maclin
Jie Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Corp of North America
Original Assignee
Guilford Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/145,185 external-priority patent/US6121278A/en
Application filed by Guilford Pharmaceuticals Inc filed Critical Guilford Pharmaceuticals Inc
Publication of AU9298198A publication Critical patent/AU9298198A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
AU92981/98A 1997-09-03 1998-09-02 Di-n-heterocyclic compounds, methods, and compositions for inhibiting parp activity Abandoned AU9298198A (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US92252097A 1997-09-03 1997-09-03
US08922520 1997-09-03
US7951198A 1998-05-15 1998-05-15
US09079511 1998-05-15
US09/145,185 US6121278A (en) 1997-09-03 1998-09-01 Di-n-heterocyclic compounds, methods, and compositions for inhibiting parp activity
US09145185 1998-09-01
PCT/US1998/018188 WO1999011644A1 (fr) 1997-09-03 1998-09-02 Composes di-n-heterocycliques, et procedes et compositions permettant d'inhiber l'activite de la parp

Publications (1)

Publication Number Publication Date
AU9298198A true AU9298198A (en) 1999-03-22

Family

ID=27373496

Family Applications (1)

Application Number Title Priority Date Filing Date
AU92981/98A Abandoned AU9298198A (en) 1997-09-03 1998-09-02 Di-n-heterocyclic compounds, methods, and compositions for inhibiting parp activity

Country Status (2)

Country Link
AU (1) AU9298198A (fr)
WO (1) WO1999011644A1 (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6235748B1 (en) 1997-09-03 2001-05-22 Guilford Pharmaceuticals Inc. Oxo-substituted compounds, process of making, and compositions and methods for inhibiting parp activity
CA2332279A1 (fr) * 1998-05-15 1999-11-25 Jia-He Li Composes de carboxamide, compositions et methodes d'inhibition de l'activite de type poly(adp-ribose) polymerase (parp)
US20030078212A1 (en) * 1998-10-30 2003-04-24 Jia-He Li Pharmaceutical compositions containing poly(adp-ribose) glycohydrolase inhibitors and methods of using the same
SI20691B (sl) 1999-01-11 2008-10-31 Agouron Pharma Triciklični inhibitorji poli(ADP-riboza) polimeraz
JP2001002572A (ja) * 1999-04-19 2001-01-09 Sankyo Co Ltd ニューロトロフィン作用増強剤
ECSP003637A (es) 1999-08-31 2002-03-25 Agouron Pharma Inhibidores triciclicos de poli (adp-ribosa) polimerasas
KR20010087401A (ko) * 1999-09-28 2001-09-15 스타르크, 카르크 아제피노인돌 유도체, 그의 제법 및 용도
US6531464B1 (en) 1999-12-07 2003-03-11 Inotek Pharmaceutical Corporation Methods for the treatment of neurodegenerative disorders using substituted phenanthridinone derivatives
US6476048B1 (en) 1999-12-07 2002-11-05 Inotek Pharamaceuticals Corporation Substituted phenanthridinones and methods of use thereof
US6534651B2 (en) 2000-04-06 2003-03-18 Inotek Pharmaceuticals Corp. 7-Substituted isoindolinone inhibitors of inflammation and reperfusion injury and methods of use thereof
US7122679B2 (en) 2000-05-09 2006-10-17 Cephalon, Inc. Multicyclic compounds and the use thereof
US6956035B2 (en) 2001-08-31 2005-10-18 Inotek Pharmaceuticals Corporation Isoquinoline derivatives and methods of use thereof
US20030096833A1 (en) 2001-08-31 2003-05-22 Jagtap Prakash G. Substituted ideno[1,2-c]isoquinoline derivatives and methods of use thereof
BRPI0407757A (pt) 2003-02-28 2006-02-14 Inotek Pharmaceuticals Corp derivados de benzamida tetracìclica e métodos de uso dos mesmos
EP1722797A4 (fr) 2004-02-26 2008-03-19 Inotek Pharmaceuticals Corp Derives d'isoquinoline et methodes d'utilisation
MX2007008771A (es) 2005-01-19 2007-09-11 Mgi Gp Inc Compuestos de diazabenzo [des] antracen-3-ona y metodos para inhibir parp.
US7381722B2 (en) 2005-02-25 2008-06-03 Inotek Pharmaceuticals Corporation Tetracyclic amino and carboxamido compounds and methods of use thereof
KR20080039508A (ko) 2005-08-24 2008-05-07 이노텍 파마슈티컬스 코포레이션 인데노이소퀴놀리논 유사체 및 이의 사용 방법
US9150628B2 (en) 2005-11-14 2015-10-06 Centre National De La Recherche Scientifique (Cnrs) PARP inhibitors
CA2677046A1 (fr) 2007-02-28 2008-09-04 Inotek Pharmaceuticals Corporation Analogues d'indenoisoquinoleinone et procedes d'utilisation de ceux-ci
JP5439380B2 (ja) 2007-10-03 2014-03-12 エーザイ インク． Ｐａｒｐ阻害化合物、組成物及び使用方法
JP5699223B2 (ja) 2010-12-02 2015-04-08 シャンハイ デュァ ノボ ファルマテック カンパニー リミテッド 複素環誘導体、その合成法および医療用途
TW201702218A (zh) 2014-12-12 2017-01-16 美國杰克森實驗室 關於治療癌症、自體免疫疾病及神經退化性疾病之組合物及方法
US11261466B2 (en) 2015-03-02 2022-03-01 Sinai Health System Homologous recombination factors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9404485D0 (en) * 1994-03-09 1994-04-20 Cancer Res Campaign Tech Benzamide analogues
US5589483A (en) * 1994-12-21 1996-12-31 Geron Corporation Isoquinoline poly (ADP-ribose) polymerase inhibitors to treat skin diseases associated with cellular senescence

Also Published As

Publication number Publication date
WO1999011644A1 (fr) 1999-03-11

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase