AU8552098A - Pyrazoloquinolinone derivatives as gaba alpha 5 receptor inverse agonists - Google Patents

Pyrazoloquinolinone derivatives as gaba alpha 5 receptor inverse agonists

Info

Publication number
AU8552098A
AU8552098A AU85520/98A AU8552098A AU8552098A AU 8552098 A AU8552098 A AU 8552098A AU 85520/98 A AU85520/98 A AU 85520/98A AU 8552098 A AU8552098 A AU 8552098A AU 8552098 A AU8552098 A AU 8552098A
Authority
AU
Australia
Prior art keywords
inverse agonists
receptor inverse
pyrazoloquinolinone
derivatives
gaba alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU85520/98A
Inventor
Sylvie Bourrain
Angus Murray Macleod
Graham Andrew Showell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon Pharma UK Ltd
Original Assignee
Merck Sharp and Dohme Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp and Dohme Ltd filed Critical Merck Sharp and Dohme Ltd
Publication of AU8552098A publication Critical patent/AU8552098A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU85520/98A 1997-08-01 1998-07-30 Pyrazoloquinolinone derivatives as gaba alpha 5 receptor inverse agonists Abandoned AU8552098A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9716345.5A GB9716345D0 (en) 1997-08-01 1997-08-01 Therapeutic compounds
GB9716345 1997-08-01
PCT/GB1998/002289 WO1999006400A1 (en) 1997-08-01 1998-07-30 Pyrazoloquinolinone derivatives as gaba alpha 5 receptor inverse agonists

Publications (1)

Publication Number Publication Date
AU8552098A true AU8552098A (en) 1999-02-22

Family

ID=10816865

Family Applications (1)

Application Number Title Priority Date Filing Date
AU85520/98A Abandoned AU8552098A (en) 1997-08-01 1998-07-30 Pyrazoloquinolinone derivatives as gaba alpha 5 receptor inverse agonists

Country Status (3)

Country Link
AU (1) AU8552098A (en)
GB (1) GB9716345D0 (en)
WO (1) WO1999006400A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0812369A2 (en) * 2007-06-08 2016-08-09 Helicon Therapeutics Inc compound and pharmaceutical composition and methods of modulating one or more gabaa subtypes and treating cognitive dysfunction, psychiatric disorder and enhancement of cognitive function in animal and uses of compound or pharmaceutical composition.
WO2008154442A1 (en) * 2007-06-08 2008-12-18 Helicon Therapeutics, Inc. Therapeutic pyrazoloquinoline urea derivatives
EP2188284A2 (en) * 2007-08-14 2010-05-26 Novartis Ag Tricyclic heterocyclic compounds as gaba a modulators
JP2010535844A (en) * 2007-08-14 2010-11-25 ノバルティス アーゲー Pyrazoloquinoline and pyrazolonaphthyridine derivatives as GABA alpha ligands
US20150374705A1 (en) 2012-02-14 2015-12-31 Shanghai Institues for Biological Sciences Substances for treatment or relief of pain
NZ701958A (en) * 2012-05-16 2016-08-26 Archer Daniels Midland Co Emulsifier for solubilizing polar solvents in oils and polyols

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0214092A1 (en) * 1985-08-08 1987-03-11 Ciba-Geigy Ag Enhanced absorption of psychoactive 2-aryl-pyrazolo quinolines as a solid molecular dispersion in polyvinylpyrrolidone

Also Published As

Publication number Publication date
GB9716345D0 (en) 1997-10-08
WO1999006400A1 (en) 1999-02-11

Similar Documents

Publication Publication Date Title
AU1052599A (en) Retinoid receptor agonists
AU5343298A (en) 5-ht2c receptor agonists and aminoalkylindazole derivatives
AU1285499A (en) Somatostatin agonists
AU5203999A (en) Beta3-adrenergic receptor agonists
AP9801356A0 (en) Prostaglandin agonists
AU3783497A (en) Metabotropic glutamate receptor agonists
AU1121799A (en) Emulsion composition monitor
HRP980404B1 (en) Substituted 1,2,3,4-tetrahydronaphthalene derivatives
AU7349298A (en) Prostaglandin agonists
HU9601240D0 (en) Beta-adrenerg agonists
AU5335798A (en) Stomatic composition
AU8747498A (en) Food-preservative composition
AU8182098A (en) Parkinson's disease tests
AU8748798A (en) 4-aminoquinazoline derivatives
AU4493496A (en) Substituted 1,4-piperazine-heteroaryl derivatives as 5-ht1d receptor agonists
AU8121998A (en) Composition
AU8552098A (en) Pyrazoloquinolinone derivatives as gaba alpha 5 receptor inverse agonists
AUPO863197A0 (en) Novel derivatives
AU4622597A (en) Novel pyranoside derivatives
AU6994396A (en) Substituted indolylpropyl-piperazine derivatives as 5-ht1dalpha agonists
AU2575399A (en) Oxazole derivatives as serotonin-1a receptor agonists
AU8551298A (en) Aryl-substituted pyrazoloquinolinone derivatives as gaba alpha 5 receptor inverse agonists
AU1098499A (en) Emulsifier-lipid composition
AU8552198A (en) 2-aryl-2,5-dihydro-pyrazolo{4,3-c}quinolin-3-ones as gaba alpha 5 receptor inverse agonists
ZA9710576B (en) 2-imidazolinylaminoindazole compounds useful as alpha-2-adrenoceptor agonists

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase