AU8551298A - Aryl-substituted pyrazoloquinolinone derivatives as gaba alpha 5 receptor inverse agonists - Google Patents

Aryl-substituted pyrazoloquinolinone derivatives as gaba alpha 5 receptor inverse agonists

Info

Publication number
AU8551298A
AU8551298A AU85512/98A AU8551298A AU8551298A AU 8551298 A AU8551298 A AU 8551298A AU 85512/98 A AU85512/98 A AU 85512/98A AU 8551298 A AU8551298 A AU 8551298A AU 8551298 A AU8551298 A AU 8551298A
Authority
AU
Australia
Prior art keywords
aryl
substituted
inverse agonists
receptor inverse
pyrazoloquinolinone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU85512/98A
Inventor
Sylvie Bourrain
Helen Jane Bryant
Angus Murray Macleod
Graham Andrew Showell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon Pharma UK Ltd
Original Assignee
Merck Sharp and Dohme Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp and Dohme Ltd filed Critical Merck Sharp and Dohme Ltd
Publication of AU8551298A publication Critical patent/AU8551298A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU85512/98A 1997-08-01 1998-07-30 Aryl-substituted pyrazoloquinolinone derivatives as gaba alpha 5 receptor inverse agonists Abandoned AU8551298A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9716344 1997-08-01
GBGB9716344.8A GB9716344D0 (en) 1997-08-01 1997-08-01 Therapeutic compounds
PCT/GB1998/002279 WO1999006399A1 (en) 1997-08-01 1998-07-30 Aryl-substituted pyrazoloquinolinone derivatives as gaba alpha 5 receptor inverse agonists

Publications (1)

Publication Number Publication Date
AU8551298A true AU8551298A (en) 1999-02-22

Family

ID=10816864

Family Applications (1)

Application Number Title Priority Date Filing Date
AU85512/98A Abandoned AU8551298A (en) 1997-08-01 1998-07-30 Aryl-substituted pyrazoloquinolinone derivatives as gaba alpha 5 receptor inverse agonists

Country Status (3)

Country Link
AU (1) AU8551298A (en)
GB (1) GB9716344D0 (en)
WO (1) WO1999006399A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9929685D0 (en) * 1999-12-15 2000-02-09 Merck Sharp & Dohme Therapeutic agents
CA2688405A1 (en) * 2007-06-08 2008-12-18 Helicon Therapeutics, Inc. Therapeutic pyrazoloquinoline urea derivatives
KR20100036306A (en) * 2007-06-08 2010-04-07 헬리콘 테라퓨틱스 인코퍼레이티드 Therapeutic pyrazolonaphthyridine derivatives
US20150374705A1 (en) 2012-02-14 2015-12-31 Shanghai Institues for Biological Sciences Substances for treatment or relief of pain
US10865203B2 (en) * 2015-06-03 2020-12-15 Uwm Research Foundation, Inc. Ligands selective to alpha 6 subunit-containing GABAA receptors and their methods of use

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4312870A (en) * 1979-06-21 1982-01-26 Ciba-Geigy Corporation Pyrazoloquinolines
GB9503601D0 (en) * 1995-02-23 1995-04-12 Merck Sharp & Dohme Method of treatment and method of manufacture of medicament

Also Published As

Publication number Publication date
GB9716344D0 (en) 1997-10-08
WO1999006399A1 (en) 1999-02-11

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase