AU8296998A - 2-aminoalkylaminoquinolines as dopamine d4 ligands - Google Patents

2-aminoalkylaminoquinolines as dopamine d4 ligands

Info

Publication number
AU8296998A
AU8296998A AU82969/98A AU8296998A AU8296998A AU 8296998 A AU8296998 A AU 8296998A AU 82969/98 A AU82969/98 A AU 82969/98A AU 8296998 A AU8296998 A AU 8296998A AU 8296998 A AU8296998 A AU 8296998A
Authority
AU
Australia
Prior art keywords
aminoalkylaminoquinolines
dopamine
ligands
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU82969/98A
Inventor
Xiao-Shu He
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Neurogen Corp
Original Assignee
Neurogen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurogen Corp filed Critical Neurogen Corp
Publication of AU8296998A publication Critical patent/AU8296998A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
AU82969/98A 1997-06-13 1998-06-11 2-aminoalkylaminoquinolines as dopamine d4 ligands Abandoned AU8296998A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87486497A 1997-06-13 1997-06-13
US08874864 1997-06-13
PCT/US1998/014235 WO1998056786A1 (en) 1997-06-13 1998-06-11 2-aminoalkylaminoquinolines as dopamine d4 ligands

Publications (1)

Publication Number Publication Date
AU8296998A true AU8296998A (en) 1998-12-30

Family

ID=25364745

Family Applications (1)

Application Number Title Priority Date Filing Date
AU82969/98A Abandoned AU8296998A (en) 1997-06-13 1998-06-11 2-aminoalkylaminoquinolines as dopamine d4 ligands

Country Status (5)

Country Link
EP (1) EP0991642A1 (en)
JP (1) JP2002504125A (en)
AU (1) AU8296998A (en)
CA (1) CA2293480A1 (en)
WO (1) WO1998056786A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6281216B1 (en) * 1998-02-09 2001-08-28 Duphar International Research B.V. 2-aminoquinoline derivatives having d4-agonistic activity
US6284759B1 (en) 1998-09-30 2001-09-04 Neurogen Corporation 2-piperazinoalkylaminobenzo-azole derivatives: dopamine receptor subtype specific ligands
EP1117663A2 (en) * 1998-09-30 2001-07-25 Neurogen Corporation 2-piperazino alkylamino benzoazole derivatives: dopamine receptor subtype specific ligands
FR2877005A1 (en) * 2004-10-22 2006-04-28 Bioprojet Soc Civ Ile NEW ARYLPIPERAZINE DERIVATIVES

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5681956A (en) * 1990-12-28 1997-10-28 Neurogen Corporation 4-aryl substituted piperazinylmethyl phenylimidazole derivatives; a new class of dopamine receptor subtype specific ligands
AU645681B2 (en) * 1991-05-02 1994-01-20 John Wyeth & Brother Limited Piperazine derivatives
WO1994020471A1 (en) * 1993-03-05 1994-09-15 Merck Sharp & Dohme Limited Quinolone derivatives as dopamine d4 ligands
WO1996039403A1 (en) * 1995-06-05 1996-12-12 Neurogen Corporation 1-(n'-(arylalkylaminoalkyl)) aminoisoindoles as dopamine receptor ligands

Also Published As

Publication number Publication date
JP2002504125A (en) 2002-02-05
WO1998056786A1 (en) 1998-12-17
EP0991642A1 (en) 2000-04-12
CA2293480A1 (en) 1998-12-17

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase