AU8077801A - Non-sedating barbiturate compounds as neuroprotective agents - Google Patents
Non-sedating barbiturate compounds as neuroprotective agentsInfo
- Publication number
- AU8077801A AU8077801A AU8077801A AU8077801A AU8077801A AU 8077801 A AU8077801 A AU 8077801A AU 8077801 A AU8077801 A AU 8077801A AU 8077801 A AU8077801 A AU 8077801A AU 8077801 A AU8077801 A AU 8077801A
- Authority
- AU
- Australia
- Prior art keywords
- neuroprotective agents
- sedative
- sedating barbiturate
- barbiturate compounds
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- HNYOPLTXPVRDBG-UHFFFAOYSA-N barbituric acid Chemical class O=C1CC(=O)NC(=O)N1 HNYOPLTXPVRDBG-UHFFFAOYSA-N 0.000 title abstract 2
- 239000004090 neuroprotective agent Substances 0.000 title 1
- 239000000932 sedative agent Substances 0.000 abstract 3
- 230000001624 sedative effect Effects 0.000 abstract 3
- 229940125717 barbiturate Drugs 0.000 abstract 2
- 230000004112 neuroprotection Effects 0.000 abstract 2
- IKVPZYAOGOJTLK-UHFFFAOYSA-N 5,5-diphenyl-1,3-diazinane-2,4,6-trione Chemical compound O=C1NC(=O)NC(=O)C1(C=1C=CC=CC=1)C1=CC=CC=C1 IKVPZYAOGOJTLK-UHFFFAOYSA-N 0.000 abstract 1
- 206010002091 Anaesthesia Diseases 0.000 abstract 1
- 230000037005 anaesthesia Effects 0.000 abstract 1
- -1 barbiturate compound Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000000324 neuroprotective effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
- A61K31/515—Barbituric acids; Derivatives thereof, e.g. sodium pentobarbital
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22167200P | 2000-07-26 | 2000-07-26 | |
| PCT/US2001/023420 WO2002007729A1 (en) | 2000-07-26 | 2001-07-26 | Non-sedating barbiturate compounds as neuroprotective agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU8077801A true AU8077801A (en) | 2002-02-05 |
Family
ID=22828824
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU8077801A Pending AU8077801A (en) | 2000-07-26 | 2001-07-26 | Non-sedating barbiturate compounds as neuroprotective agents |
| AU2001280778A Ceased AU2001280778B2 (en) | 2000-07-26 | 2001-07-26 | Non-sedating barbiturate compounds as neuroprotective agents |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001280778A Ceased AU2001280778B2 (en) | 2000-07-26 | 2001-07-26 | Non-sedating barbiturate compounds as neuroprotective agents |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1311270B1 (https=) |
| JP (1) | JP5047442B2 (https=) |
| CN (2) | CN100522172C (https=) |
| AT (1) | ATE383159T1 (https=) |
| AU (2) | AU8077801A (https=) |
| BR (1) | BR0112775A (https=) |
| CA (1) | CA2416535C (https=) |
| DE (1) | DE60132337T2 (https=) |
| ES (1) | ES2300349T3 (https=) |
| IL (3) | IL154060A0 (https=) |
| MX (1) | MXPA03000824A (https=) |
| PT (1) | PT1311270E (https=) |
| WO (1) | WO2002007729A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6093820A (en) | 1997-10-02 | 2000-07-25 | Taro Pharmaceutical Industries Ltd. | Method and reagents for N-alkylating ureides |
| WO2002007729A1 (en) * | 2000-07-26 | 2002-01-31 | Taro Pharmaceutical Industries Ltd. | Non-sedating barbiturate compounds as neuroprotective agents |
| US6939873B2 (en) | 2000-07-26 | 2005-09-06 | Taro Pharmaceuticals Industries Limited | Non-sedating barbituric acid derivatives |
| US7683071B2 (en) | 2000-07-26 | 2010-03-23 | Taro Pharmaceuticals Industries Ltd. | Composition and method for improved bioavailability and enhanced brain delivery of 5,5-diphenyl barbituric acid |
| US6756379B2 (en) | 2001-07-26 | 2004-06-29 | Taro Pharmaceutical Industries Ltd. | Non-sedating barbiturate compounds as neuroprotective agents |
| EP1485101A4 (en) * | 2002-01-30 | 2006-04-12 | Taro Pharma Ind | NON-SURFACTANT BARBITIC ACID DERIVATIVES |
| BR0314617A (pt) | 2002-10-11 | 2005-08-02 | Baxter Int | Método para cardioproteção e neuroproteção por administração intravenosa de anestésico voláteis halogenados |
| WO2004052350A2 (en) * | 2002-12-11 | 2004-06-24 | Taro Pharmaceutical Industries Limited | Method of treating movement disorders using barbituric acid derivatives |
| EP1625848A1 (en) * | 2004-08-10 | 2006-02-15 | Taro Pharmaceuticals North America, Inc. | Composition and method for enhanced delivery of 5,5-diphenyl barbituric acid |
| RU2370266C2 (ru) * | 2007-12-21 | 2009-10-20 | Федеральное государственное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова Федерального агентства по высокотехнологичной медицинской помощи" | Способ общего обезболивания |
| WO2013038427A1 (en) * | 2011-09-12 | 2013-03-21 | Council Of Scientific & Industrial Research | ARYLATED β-DICARBOIMYL COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF |
| CN102863579B (zh) * | 2012-09-14 | 2014-02-05 | 东南大学 | 一种巴比妥酸螯合树脂及其制备方法和应用 |
| EP3329279B1 (en) | 2015-10-05 | 2021-07-07 | The University of North Carolina at Chapel Hill | Decoding methods for multiplexing assays and associated fluidic devices, kits, and solid supports |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL69722A (en) * | 1983-09-14 | 1986-09-30 | Taro Pharma Ind | Oxopyrimidine derivatives and pharmaceutical compositions containing them |
| US4833148A (en) * | 1987-04-09 | 1989-05-23 | Washington University | Method of using alkenyl- or alkynyl-substituted thiobarbiturates to reduce neurotoxic injury |
| US5474990A (en) * | 1989-10-20 | 1995-12-12 | Olney; John W. | Barbiturates as safening agents in conjunction with NMDA antagonists |
| WO2002007729A1 (en) * | 2000-07-26 | 2002-01-31 | Taro Pharmaceutical Industries Ltd. | Non-sedating barbiturate compounds as neuroprotective agents |
-
2001
- 2001-07-26 WO PCT/US2001/023420 patent/WO2002007729A1/en not_active Ceased
- 2001-07-26 AT AT01959195T patent/ATE383159T1/de not_active IP Right Cessation
- 2001-07-26 CN CNB2006100813267A patent/CN100522172C/zh not_active Expired - Fee Related
- 2001-07-26 AU AU8077801A patent/AU8077801A/xx active Pending
- 2001-07-26 MX MXPA03000824A patent/MXPA03000824A/es active IP Right Grant
- 2001-07-26 CN CNB018151426A patent/CN1329032C/zh not_active Expired - Fee Related
- 2001-07-26 DE DE60132337T patent/DE60132337T2/de not_active Expired - Lifetime
- 2001-07-26 JP JP2002513464A patent/JP5047442B2/ja not_active Expired - Fee Related
- 2001-07-26 AU AU2001280778A patent/AU2001280778B2/en not_active Ceased
- 2001-07-26 ES ES01959195T patent/ES2300349T3/es not_active Expired - Lifetime
- 2001-07-26 PT PT01959195T patent/PT1311270E/pt unknown
- 2001-07-26 BR BR0112775-6A patent/BR0112775A/pt not_active Application Discontinuation
- 2001-07-26 IL IL15406001A patent/IL154060A0/xx unknown
- 2001-07-26 EP EP01959195A patent/EP1311270B1/en not_active Expired - Lifetime
- 2001-07-26 CA CA2416535A patent/CA2416535C/en not_active Expired - Fee Related
-
2003
- 2003-01-20 IL IL154060A patent/IL154060A/en not_active IP Right Cessation
-
2004
- 2004-11-03 IL IL16501704A patent/IL165017A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002007729A9 (en) | 2002-08-08 |
| ES2300349T3 (es) | 2008-06-16 |
| BR0112775A (pt) | 2003-12-30 |
| JP2004517808A (ja) | 2004-06-17 |
| EP1311270A4 (en) | 2006-04-12 |
| PT1311270E (pt) | 2008-04-15 |
| EP1311270A1 (en) | 2003-05-21 |
| CA2416535A1 (en) | 2002-01-31 |
| EP1311270B1 (en) | 2008-01-09 |
| DE60132337T2 (de) | 2009-02-12 |
| CN1461219A (zh) | 2003-12-10 |
| MXPA03000824A (es) | 2004-11-01 |
| CA2416535C (en) | 2010-11-16 |
| DE60132337D1 (de) | 2008-02-21 |
| CN100522172C (zh) | 2009-08-05 |
| CN1872067A (zh) | 2006-12-06 |
| IL165017A0 (en) | 2005-12-18 |
| IL154060A (en) | 2013-05-30 |
| WO2002007729A1 (en) | 2002-01-31 |
| ATE383159T1 (de) | 2008-01-15 |
| AU2001280778B2 (en) | 2004-09-02 |
| JP5047442B2 (ja) | 2012-10-10 |
| IL154060A0 (en) | 2003-07-31 |
| HK1100814A1 (en) | 2007-09-28 |
| CN1329032C (zh) | 2007-08-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL165017A0 (en) | Non-sedating barbiturate compounds as neuroprotective agents | |
| AU7315301A (en) | Compounds and compositions for delivering active agents | |
| MXPA01008611A (es) | Compuestos y composiciones para suministrar agentes activos. | |
| HUS1200030I1 (hu) | Dipeptidil peptidáz IV ciklopropil-kondenzált pirrolidin-bázisú inhibitorai és eljárás elõállításukra és a vegyületeket tartalmazó gyógyszerkészítmények | |
| IL140930A0 (en) | Compounds and compositions for delivering active agents | |
| IL161154A0 (en) | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | |
| IL195055A (en) | Carboxylic acid components and compounds for transporting active carriers | |
| AU2274201A (en) | Compounds and compositions for delivering active agents | |
| IL145568A0 (en) | Pharmaceutical compositions comprising dipeptidyl peptidase iv inhibitors for the promotion of growth | |
| MXPA02011632A (es) | Inhibidores de 11-beta-hidroxiesteroide deshidrogenasa tipo 1. | |
| ECSP034922A (es) | Pirrolopirimidinas | |
| MXPA03007857A (es) | Compuestos y composiciones para entregar agentes activos. | |
| PL378238A1 (pl) | Związki biaromatyczne, które aktywują receptory typu PPAR<$Egamma>, oraz ich zastosowanie w kompozycjach kosmetycznych albo farmaceutycznych | |
| AU3492100A (en) | Oxadiazole compounds and compositions for delivering active agents | |
| IL162614A (en) | Alpha tocopherol esters for use in treating culture-borne cell disease by aerosol administration | |
| MY124727A (en) | Tri-substituted phenyl derivatives and analogues. | |
| GB9907571D0 (en) | Compounds | |
| AU2001246999A1 (en) | New neurokinin antagonists for use as medicaments | |
| GR3020330T3 (en) | Novel bicyclic pyrimidine compounds, method for preparing same and pharmaceutical compositions containing said compounds. | |
| MY139228A (en) | Imidazolinylmethyl aralkylsulfonamides | |
| MY153713A (en) | A pharmaceutical composition comprising 3, 4-dihydro-3-methyl-4-oxoimidazo [5,1-d]-1,2,3,5-tetrazine-8-carboxylate | |
| EP1905441A3 (en) | Non-sedating barbiturate compounds as neuroprotective agents | |
| EP1099439A3 (en) | Use of apo B secretion/MTP inhibitors | |
| AU2001244999A1 (en) | Naphthamide neurokinin antagonists for use as medicaments | |
| PE20020903A1 (es) | Metodo para prevenir la diarrea |