AU7953598A - Screening for phosphatidylinositol related-kinase inhibitors - Google Patents
Screening for phosphatidylinositol related-kinase inhibitors Download PDFInfo
- Publication number
- AU7953598A AU7953598A AU79535/98A AU7953598A AU7953598A AU 7953598 A AU7953598 A AU 7953598A AU 79535/98 A AU79535/98 A AU 79535/98A AU 7953598 A AU7953598 A AU 7953598A AU 7953598 A AU7953598 A AU 7953598A
- Authority
- AU
- Australia
- Prior art keywords
- cells
- wortmannin
- kinase
- mtor
- phas
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- G01N2333/91205—Phosphotransferases in general
- G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases
- G01N2333/91215—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases with a definite EC number (2.7.1.-)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4886997P | 1997-06-06 | 1997-06-06 | |
US60048869 | 1997-06-06 | ||
PCT/US1998/011420 WO1998055602A1 (fr) | 1997-06-06 | 1998-06-05 | Criblage d'inhibiteurs de la kinase liee au phosphatidilynositol |
Publications (1)
Publication Number | Publication Date |
---|---|
AU7953598A true AU7953598A (en) | 1998-12-21 |
Family
ID=21956893
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU79535/98A Abandoned AU7953598A (en) | 1997-06-06 | 1998-06-05 | Screening for phosphatidylinositol related-kinase inhibitors |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0990028A4 (fr) |
AU (1) | AU7953598A (fr) |
CA (1) | CA2292540A1 (fr) |
WO (1) | WO1998055602A1 (fr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9714971D0 (en) | 1997-07-16 | 1997-09-24 | Cancer Res Campaign Tech | Assays,therapeutic methods and means |
US6387640B1 (en) | 1999-02-10 | 2002-05-14 | St. Jude Children's Research Hospital | ATM kinase modulation for screening and therapies |
US6348311B1 (en) | 1999-02-10 | 2002-02-19 | St. Jude Childre's Research Hospital | ATM kinase modulation for screening and therapies |
JP4079581B2 (ja) * | 2000-08-11 | 2008-04-23 | ユニ・チャーム株式会社 | 使い捨て着用物品 |
GB0119865D0 (en) | 2001-08-14 | 2001-10-10 | Cancer Res Campaign Tech | DNA-PK inhibitors |
GB0119863D0 (en) | 2001-08-14 | 2001-10-10 | Cancer Res Campaign Tech | DNA-PK inhibitors |
US7049313B2 (en) | 2002-02-25 | 2006-05-23 | Kudos Pharmaceuticals Ltd. | ATM inhibitors |
KR20060066722A (ko) | 2003-08-13 | 2006-06-16 | 쿠도스 파마슈티칼스 리미티드 | 아미노피론 및 atm억제제로서의 이의 용도 |
TW200616986A (en) | 2004-09-20 | 2006-06-01 | Kudos Pharm Ltd | DNA-pk inhibitors |
EP1848712A1 (fr) | 2005-02-09 | 2007-10-31 | Kudos Pharmaceuticals Ltd | Inhibiteurs d'atm |
AR054438A1 (es) | 2005-04-15 | 2007-06-27 | Kudos Pharm Ltd | Inhibidores de adn -pk |
WO2009047567A1 (fr) * | 2007-10-10 | 2009-04-16 | University Of Sheffield | Essai pour identifier des agents qui inhibent les voies atr et/ou dna-pk |
US9644037B2 (en) | 2013-10-18 | 2017-05-09 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Antibodies that specifically bind ataxia telangiectasia-mutated and RAD3-related kinase phosphorylated at position 1989 and their use |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5466716A (en) * | 1990-12-31 | 1995-11-14 | The Biomembrane Institute | Liposomal trimethylsphingosine |
US5151360A (en) * | 1990-12-31 | 1992-09-29 | Biomembrane Institute | Effect of n,n,n-trimethylsphingosine on protein kinase-c activity, melanoma cell growth in vitro, metastatic potential in vivo and human platelet aggregation |
-
1998
- 1998-06-05 AU AU79535/98A patent/AU7953598A/en not_active Abandoned
- 1998-06-05 CA CA002292540A patent/CA2292540A1/fr not_active Abandoned
- 1998-06-05 EP EP98930061A patent/EP0990028A4/fr not_active Withdrawn
- 1998-06-05 WO PCT/US1998/011420 patent/WO1998055602A1/fr not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP0990028A4 (fr) | 2000-09-27 |
WO1998055602A9 (fr) | 1999-04-08 |
EP0990028A1 (fr) | 2000-04-05 |
CA2292540A1 (fr) | 1998-12-10 |
WO1998055602A1 (fr) | 1998-12-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK5 | Application lapsed section 142(2)(e) - patent request and compl. specification not accepted |