AU778090B2 - Methods for treating mild cognitive impairment - Google Patents

Methods for treating mild cognitive impairment Download PDF

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Publication number
AU778090B2
AU778090B2 AU19283/01A AU1928301A AU778090B2 AU 778090 B2 AU778090 B2 AU 778090B2 AU 19283/01 A AU19283/01 A AU 19283/01A AU 1928301 A AU1928301 A AU 1928301A AU 778090 B2 AU778090 B2 AU 778090B2
Authority
AU
Australia
Prior art keywords
glucocorticoid receptor
receptor antagonist
cortisol
patient
mci
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU19283/01A
Other languages
English (en)
Other versions
AU1928301A (en
Inventor
Joseph K. Belanoff
Alan F. Schatzberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Corcept Therapeutics Inc
Original Assignee
Corcept Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22607362&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU778090(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Corcept Therapeutics Inc filed Critical Corcept Therapeutics Inc
Publication of AU1928301A publication Critical patent/AU1928301A/en
Application granted granted Critical
Publication of AU778090B2 publication Critical patent/AU778090B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/46Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of glucocorticosteroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
AU19283/01A 1999-11-23 2000-11-21 Methods for treating mild cognitive impairment Expired AU778090B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16743299P 1999-11-23 1999-11-23
US60/167432 1999-11-23
PCT/US2000/032260 WO2001037840A1 (en) 1999-11-23 2000-11-21 Methods for treating mild cognitive impairment

Publications (2)

Publication Number Publication Date
AU1928301A AU1928301A (en) 2001-06-04
AU778090B2 true AU778090B2 (en) 2004-11-18

Family

ID=22607362

Family Applications (1)

Application Number Title Priority Date Filing Date
AU19283/01A Expired AU778090B2 (en) 1999-11-23 2000-11-21 Methods for treating mild cognitive impairment

Country Status (7)

Country Link
US (2) US6620802B1 (cg-RX-API-DMAC7.html)
EP (1) EP1242094A4 (cg-RX-API-DMAC7.html)
JP (1) JP2003527342A (cg-RX-API-DMAC7.html)
AU (1) AU778090B2 (cg-RX-API-DMAC7.html)
CA (1) CA2389570C (cg-RX-API-DMAC7.html)
HK (1) HK1047050A1 (cg-RX-API-DMAC7.html)
WO (1) WO2001037840A1 (cg-RX-API-DMAC7.html)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010046470A1 (en) * 2000-05-10 2001-11-29 Kieko Morita Diagnoses and treatment of disorders using an alternative glucose pathway
AU2002255845B2 (en) 2001-03-23 2006-11-23 Corcept Therapeutics, Inc. Methods for treating stress disorders using glucocorticoid receptor-specific antagonists
DE60229411D1 (de) 2001-08-31 2008-11-27 Corcept Therapeutics Inc Verfahren zur hemmung der verschlechterung der kognitiven leistungsfähigkeit bei erwachsenen mit down-syndrom
EP1492541A1 (en) * 2002-04-05 2005-01-05 The University Of Edinburgh Pharmaceutical compositions comprising a 11-beta hydroxysteroid dehydrogenase inhibitor and a diuretic agent
US8237946B2 (en) * 2004-10-08 2012-08-07 Sharp Laboratories Of America, Inc. Methods and systems for imaging device accounting server redundancy
WO2006060736A2 (en) * 2004-12-03 2006-06-08 The Children's Hospital Of Philadelphia A composition and use thereof in enhancing a therapeutic effect of an antiepileptic drug
EP3260118B1 (en) * 2008-10-16 2021-03-24 The Johns Hopkins University Methods and compositions for improving cognitive function
US20110202284A1 (en) * 2010-02-10 2011-08-18 Mcreynolds Cristopher Novel groups of biomarkers for diagnosing alzheimer's disease
US10500216B2 (en) 2011-11-18 2019-12-10 Corcept Therapeutics, Inc. Optimizing mifepristone absorption
JP2016503410A (ja) * 2012-11-09 2016-02-04 スリーイー セラピューティクス コーポレイション3E Therapeutics Corporation X線造影剤組成物およびそれを使用して炎症関連症状を治療する方法
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia
CA2904767C (en) 2013-03-15 2022-06-21 Agenebio, Inc. Methods and compositions for improving cognitive function
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
US9943526B2 (en) 2015-04-21 2018-04-17 Corcept Therapeutics, Inc. Optimizing mifepristone levels for cushing's patients
EA034167B8 (ru) 2015-05-22 2021-04-27 Эйджинбайо, Инк. Фармацевтические композиции леветирацетама пролонгированного высвобождения

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3337450A1 (de) * 1983-10-12 1985-04-25 Schering AG, 1000 Berlin und 4709 Bergkamen Prostaglandine und antigestagene fuer den schwangerschaftsabbruch
EP0954317B1 (en) 1996-04-09 2007-06-06 The University Of Edinburgh Use of 7 apha-substituted steroids to treat neuropsychiatric disorders
DE69835225T2 (de) * 1997-10-06 2007-07-05 The Board Of Trustees Of The Leland Stanford Junior University, Palo Alto Methode zur behandlung von durch glycocorticoidstörungen verursachten psychosen
EP1076562B1 (en) * 1998-05-15 2006-02-15 The Board Of Trustees Of The Leland Stanford Junior University Glucocorticoid receptor antagonists for the treatment of dementia

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BEHL ET AL, EUR. JNL. OF NEUROSCIENCE 1997 VOL 9 PP912-920 *
TUOR ET AL, BRAIN RESEARCH, 1996, VOL 743, PP258-262 *

Also Published As

Publication number Publication date
US6620802B1 (en) 2003-09-16
EP1242094A1 (en) 2002-09-25
US20040019028A1 (en) 2004-01-29
JP2003527342A (ja) 2003-09-16
EP1242094A4 (en) 2004-06-16
CA2389570C (en) 2012-03-27
HK1047050A1 (zh) 2003-02-07
WO2001037840A1 (en) 2001-05-31
AU1928301A (en) 2001-06-04
CA2389570A1 (en) 2001-05-31

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired