AU778038B2 - A novel complex of human Kallikrein 2 (hK2) and protease inhibitor-6 (PI-6) in prostate tumor tissue and methods of using the complex - Google Patents
A novel complex of human Kallikrein 2 (hK2) and protease inhibitor-6 (PI-6) in prostate tumor tissue and methods of using the complex Download PDFInfo
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- AU778038B2 AU778038B2 AU27376/00A AU2737600A AU778038B2 AU 778038 B2 AU778038 B2 AU 778038B2 AU 27376/00 A AU27376/00 A AU 27376/00A AU 2737600 A AU2737600 A AU 2737600A AU 778038 B2 AU778038 B2 AU 778038B2
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- HWYHZTIRURJOHG-UHFFFAOYSA-N luminol Chemical compound O=C1NNC(=O)C2=C1C(N)=CC=C2 HWYHZTIRURJOHG-UHFFFAOYSA-N 0.000 description 1
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- 229940092253 ovalbumin Drugs 0.000 description 1
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- 229940111202 pepsin Drugs 0.000 description 1
- RXNXLAHQOVLMIE-UHFFFAOYSA-N phenyl 10-methylacridin-10-ium-9-carboxylate Chemical compound C12=CC=CC=C2[N+](C)=C2C=CC=CC2=C1C(=O)OC1=CC=CC=C1 RXNXLAHQOVLMIE-UHFFFAOYSA-N 0.000 description 1
- ZWLUXSQADUDCSB-UHFFFAOYSA-N phthalaldehyde Chemical compound O=CC1=CC=CC=C1C=O ZWLUXSQADUDCSB-UHFFFAOYSA-N 0.000 description 1
- 210000002826 placenta Anatomy 0.000 description 1
- 210000005059 placental tissue Anatomy 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 201000005825 prostate adenocarcinoma Diseases 0.000 description 1
- 201000001514 prostate carcinoma Diseases 0.000 description 1
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- 238000011471 prostatectomy Methods 0.000 description 1
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- 238000001742 protein purification Methods 0.000 description 1
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- 108020003175 receptors Proteins 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6445—Kallikreins (3.4.21.34; 3.4.21.35)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8121—Serpins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/803—Stabe free radicals, e.g. spin immunoassay
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/828—Cancer
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/266,957 US6284873B1 (en) | 1999-03-12 | 1999-03-12 | Complex of human kallikrein 2 (hK2) and protease inhibitor-6 (PI-6) in prostate tumor tissue and methods of using the complex |
| US09/266957 | 1999-03-12 | ||
| PCT/US2000/001937 WO2000055308A1 (en) | 1999-03-12 | 2000-01-26 | A NOVEL COMPLEX OF HUMAN KALLIKREIN 2 (hK2) AND PROTEASE INHIBITOR-6 (PI-6) IN PROSTATE TUMOR TISSUE AND METHODS OF USING THE COMPLEX |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2737600A AU2737600A (en) | 2000-10-04 |
| AU778038B2 true AU778038B2 (en) | 2004-11-11 |
Family
ID=23016693
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU27376/00A Ceased AU778038B2 (en) | 1999-03-12 | 2000-01-26 | A novel complex of human Kallikrein 2 (hK2) and protease inhibitor-6 (PI-6) in prostate tumor tissue and methods of using the complex |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US6284873B1 (https=) |
| EP (1) | EP1159411A1 (https=) |
| JP (1) | JP2002538818A (https=) |
| AU (1) | AU778038B2 (https=) |
| CA (1) | CA2365540A1 (https=) |
| WO (1) | WO2000055308A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2521410C (en) | 2003-04-04 | 2014-06-03 | Universite De Lausanne | Inhibitor proteins of a protease and use thereof |
| US20040242461A1 (en) * | 2003-04-08 | 2004-12-02 | Schneider Michael D. | Modulators of telomere stability |
| ES2311818T3 (es) * | 2003-04-28 | 2009-02-16 | JOHNSON & JOHNSON MEDICAL LTD. | Apositos terapeuticos sensibles al dolor. |
| GB2408207A (en) | 2003-11-24 | 2005-05-25 | Johnson & Johnson Medical Ltd | Wound dressing for the controlled release of therapeutic agents comprising also an inhibitor of a protease enzyme & a linker group cleavable by such an enzyme |
| CN101310185A (zh) * | 2005-09-19 | 2008-11-19 | 约翰·霍普金斯大学 | 前列腺癌的生物标记 |
| CN103229057B (zh) * | 2010-09-23 | 2016-08-10 | 生物概念股份有限公司 | 用于信号放大的方法和试剂 |
| JP7355140B2 (ja) * | 2022-02-28 | 2023-10-03 | 住友ベークライト株式会社 | セリンプロテアーゼの検出用または測定用試薬 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4731326A (en) * | 1984-06-04 | 1988-03-15 | Ortho Diagnostic Systems Inc. | Disease diagnosis by detection of shed normal tissue antigens |
| US5730968A (en) * | 1994-03-31 | 1998-03-24 | Sterling Winthrop Inc. | Segmented chelating polymers as imaging and therapeutic agents |
-
1999
- 1999-03-12 US US09/266,957 patent/US6284873B1/en not_active Expired - Fee Related
-
2000
- 2000-01-26 AU AU27376/00A patent/AU778038B2/en not_active Ceased
- 2000-01-26 EP EP00905737A patent/EP1159411A1/en not_active Withdrawn
- 2000-01-26 WO PCT/US2000/001937 patent/WO2000055308A1/en not_active Ceased
- 2000-01-26 JP JP2000605726A patent/JP2002538818A/ja active Pending
- 2000-01-26 CA CA002365540A patent/CA2365540A1/en not_active Abandoned
- 2000-09-22 US US09/667,288 patent/US6472143B1/en not_active Expired - Lifetime
-
2001
- 2001-06-15 US US09/882,648 patent/US20010031860A1/en not_active Abandoned
Non-Patent Citations (1)
| Title |
|---|
| ISR & IPER RELIED UPON * |
Also Published As
| Publication number | Publication date |
|---|---|
| US6472143B1 (en) | 2002-10-29 |
| AU2737600A (en) | 2000-10-04 |
| JP2002538818A (ja) | 2002-11-19 |
| CA2365540A1 (en) | 2000-09-21 |
| WO2000055308A1 (en) | 2000-09-21 |
| US20010031860A1 (en) | 2001-10-18 |
| US6284873B1 (en) | 2001-09-04 |
| EP1159411A1 (en) | 2001-12-05 |
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