AU765144B2 - Methods and compositions for use in perfusion applications - Google Patents

Methods and compositions for use in perfusion applications Download PDF

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Publication number
AU765144B2
AU765144B2 AU33497/00A AU3349700A AU765144B2 AU 765144 B2 AU765144 B2 AU 765144B2 AU 33497/00 A AU33497/00 A AU 33497/00A AU 3349700 A AU3349700 A AU 3349700A AU 765144 B2 AU765144 B2 AU 765144B2
Authority
AU
Australia
Prior art keywords
subject
solution
blood
plasma
usually
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU33497/00A
Other languages
English (en)
Other versions
AU3349700A (en
Inventor
Paul E. Segall
Hal Sternberg
Harold D. Waitz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lineage Cell Therapeutics Inc
Original Assignee
Biotime Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotime Inc filed Critical Biotime Inc
Publication of AU3349700A publication Critical patent/AU3349700A/en
Application granted granted Critical
Publication of AU765144B2 publication Critical patent/AU765144B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/12Chemical aspects of preservation
    • A01N1/122Preservation or perfusion media
    • A01N1/126Physiologically active agents, e.g. antioxidants or nutrients
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/718Starch or degraded starch, e.g. amylose, amylopectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/14Alkali metal chlorides; Alkaline earth metal chlorides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • External Artificial Organs (AREA)
AU33497/00A 1999-02-03 2000-01-24 Methods and compositions for use in perfusion applications Ceased AU765144B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/243921 1999-02-03
US09/243,921 US6589223B1 (en) 1999-02-03 1999-02-03 Method and compositions for use in perfusion applications
PCT/US2000/001703 WO2000045873A1 (en) 1999-02-03 2000-01-24 Methods and compositions for use in perfusion applications

Publications (2)

Publication Number Publication Date
AU3349700A AU3349700A (en) 2000-08-25
AU765144B2 true AU765144B2 (en) 2003-09-11

Family

ID=22920663

Family Applications (1)

Application Number Title Priority Date Filing Date
AU33497/00A Ceased AU765144B2 (en) 1999-02-03 2000-01-24 Methods and compositions for use in perfusion applications

Country Status (14)

Country Link
US (3) US6589223B1 (enExample)
EP (1) EP1150728A4 (enExample)
JP (2) JP2002536078A (enExample)
CN (1) CN1200742C (enExample)
AR (1) AR022482A1 (enExample)
AU (1) AU765144B2 (enExample)
BR (1) BR0008006A (enExample)
CA (1) CA2362051C (enExample)
EA (1) EA003171B1 (enExample)
IL (1) IL144710A0 (enExample)
MX (1) MXPA01007875A (enExample)
TW (1) TW542728B (enExample)
WO (1) WO2000045873A1 (enExample)
ZA (1) ZA200107243B (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8409846B2 (en) 1997-09-23 2013-04-02 The United States Of America As Represented By The Department Of Veteran Affairs Compositions, methods and devices for maintaining an organ
US6589223B1 (en) * 1999-02-03 2003-07-08 Biotime, Inc. Method and compositions for use in perfusion applications
US6718735B2 (en) * 2002-03-19 2004-04-13 Baxter International Inc. Albumin in a flexible polymeric container
US7354342B2 (en) * 2003-07-30 2008-04-08 Igt Gaming device having a multiple coordinate award distributor including award percentages
US8304181B2 (en) 2004-10-07 2012-11-06 Transmedics, Inc. Method for ex-vivo organ care and for using lactate as an indication of donor organ status
US9301519B2 (en) * 2004-10-07 2016-04-05 Transmedics, Inc. Systems and methods for ex-vivo organ care
US12010987B2 (en) 2004-10-07 2024-06-18 Transmedics, Inc. Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
US8585380B2 (en) 2004-10-07 2013-11-19 Transmedics, Inc. Systems and methods for ex-vivo organ care
US20100121273A1 (en) * 2005-06-22 2010-05-13 Kochanek Patrick M Emergency preservation and resuscitation methods
US9078428B2 (en) 2005-06-28 2015-07-14 Transmedics, Inc. Systems, methods, compositions and solutions for perfusing an organ
US7712094B2 (en) * 2005-12-22 2010-05-04 Alan Joshua Shapiro Method and apparatus for replicating a panoplex onto a storage medium from a master
DK1942726T3 (en) * 2006-04-19 2017-04-10 Transmedics Inc METHODS FOR EX VIVO ORGANIC CARE
US9457179B2 (en) 2007-03-20 2016-10-04 Transmedics, Inc. Systems for monitoring and applying electrical currents in an organ perfusion system
KR101183965B1 (ko) * 2007-10-05 2012-09-18 후소 야쿠힝 고교 가부시끼가이샤 안정한 탄산수소 이온 함유 약액
US20090123436A1 (en) * 2007-11-08 2009-05-14 Surmodics, Inc. Cryopreservative compositions and methods
US9247728B2 (en) 2008-01-31 2016-02-02 Transmedics, Inc. Systems and methods for ex vivo lung care
SE534527C2 (sv) * 2009-09-24 2011-09-20 Vivoline Medical Ab Förfarande, anordning och vätska för behandling av ett hjärta efter uttagning
DK4032401T3 (da) 2011-04-14 2025-12-15 Transmedics Inc Fremgangsmåde til fremstilling af en organplejeopløsning til maskinperfusion ex-vivo af donorlunger
US8579880B2 (en) * 2012-03-01 2013-11-12 Outcome Solutions, Llc Devices and methods for making and administering an intravenous liquid with supersaturated dissolved gas
IL303658B2 (en) 2014-06-02 2024-07-01 Transmedics Inc Ex vivo organ care system
DK3229588T3 (da) 2014-12-12 2025-06-23 Transmedics Inc Anordning og fremgangsmåde til organperfusion
DK3347084T3 (da) 2015-09-09 2021-02-15 Transmedics Inc Aortakanyle til ex vivo-organplejesystem
DK3462861T5 (da) 2016-05-30 2024-01-08 Transmedics Inc Fremgangsmåde til ex vivo-lungeventilati on med et varierende udvendigt tryk

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5613944A (en) * 1993-06-04 1997-03-25 Biotime, Inc. Plasma-like substance
US5730720A (en) * 1995-08-18 1998-03-24 Ip Scientific, Inc. Perfusion hyperthermia treatment system and method

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3677024A (en) 1970-01-20 1972-07-18 Paul E Segall Preservation and storage of biologic materials
US3937821A (en) 1971-08-21 1976-02-10 Kyorin Seiyaku Kabushiki Kaisha Plasma substitute including artificial starch and method for the preparation thereof
US4001401A (en) 1975-02-02 1977-01-04 Alza Corporation Blood substitute and blood plasma expander comprising polyhemoglobin
US4061736A (en) 1975-02-02 1977-12-06 Alza Corporation Pharmaceutically acceptable intramolecularly cross-linked, stromal-free hemoglobin
DE2801123C2 (de) 1977-01-26 1986-01-02 Armour Pharma GmbH & Co KG, 3440 Eschwege Verfahren zur Herstellung eines intravenös applizierbaren Serumeiweiß-Präparates
EP0185759B2 (en) 1984-06-22 2004-06-02 Btg International Limited Electrolyte solutions and (in vivo) use thereof
US5084377A (en) 1984-09-19 1992-01-28 Larry Rowan Cryogenic suspension method
US4908350A (en) 1985-10-31 1990-03-13 The Regents Of The University Of California Hyperosmotic/hyperoncotic solutions for resuscitation of hypodynamic shock
US5210083A (en) 1986-07-17 1993-05-11 Ed. Geistlich Sohne A.G. Fur Chemische Industrie Pharmaceutical compositions
JPS6360931A (ja) 1986-08-29 1988-03-17 Noboru Sato 血液または血液製剤保存液およびこれを用いた血液または血液製剤の保存方法
US4927806A (en) 1987-04-23 1990-05-22 The Regents Of The University Of California Saturated salt/concentrated dextran formulation to treat hemorrhage
WO1989005659A1 (en) 1987-12-24 1989-06-29 Borody Thomas J Orthostatic lavage solutions
US5130230A (en) * 1988-05-02 1992-07-14 Cryomedical Sciences, Inc. Blood substitute
US4923442A (en) * 1988-05-02 1990-05-08 Cryomedical Sciences Inc. Blood substitute
USRE34077E (en) * 1988-05-02 1992-09-22 Cryomedical Sciences, Inc. Blood substitute
US5082831A (en) 1989-12-05 1992-01-21 Cryovita Laboratories, Inc. Total body washout solution and method of use
US5171526A (en) 1990-01-05 1992-12-15 Allergan, Inc. Ophthalmic compositions and methods for preserving and using same
CA2066374C (en) 1991-04-19 2002-01-29 Paul E. Segall Solution for perfusing primates
EP0663821A4 (en) 1991-08-08 1997-09-17 Leigh D Segel BLOOD SUBSTITUTE WITH FLUOROCARBON.
US5334142A (en) * 1991-09-09 1994-08-02 New York University Selective aortic perfusion system
US5374428A (en) * 1993-03-23 1994-12-20 Kansas State University Research Foundation Supplementation of protein diets with di- and tripeptides
US5407428A (en) 1993-06-04 1995-04-18 Biotime, Inc. Solutions for use as plasma expanders and substitutes
US5405742A (en) * 1993-07-16 1995-04-11 Cyromedical Sciences, Inc. Solutions for tissue preservation and bloodless surgery and methods using same
US6218099B1 (en) * 1994-06-03 2001-04-17 Biotime, Inc. Methods and compositions for use in perfusion applications
US6589223B1 (en) * 1999-02-03 2003-07-08 Biotime, Inc. Method and compositions for use in perfusion applications

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5613944A (en) * 1993-06-04 1997-03-25 Biotime, Inc. Plasma-like substance
US5968726A (en) * 1993-06-04 1999-10-19 Biotime, Inc. Plasma-like solution
US5730720A (en) * 1995-08-18 1998-03-24 Ip Scientific, Inc. Perfusion hyperthermia treatment system and method

Also Published As

Publication number Publication date
CN1200742C (zh) 2005-05-11
CA2362051A1 (en) 2000-08-10
AU3349700A (en) 2000-08-25
EP1150728A4 (en) 2004-09-29
EA200100855A1 (ru) 2002-02-28
JP2002536078A (ja) 2002-10-29
BR0008006A (pt) 2001-12-04
MXPA01007875A (es) 2002-08-20
JP5180912B2 (ja) 2013-04-10
TW542728B (en) 2003-07-21
US7503913B2 (en) 2009-03-17
JP2009242404A (ja) 2009-10-22
AR022482A1 (es) 2002-09-04
IL144710A0 (en) 2002-06-30
CN1346286A (zh) 2002-04-24
EA003171B1 (ru) 2003-02-27
US20040018966A1 (en) 2004-01-29
US6589223B1 (en) 2003-07-08
ZA200107243B (en) 2002-09-02
US20060088606A1 (en) 2006-04-27
WO2000045873A1 (en) 2000-08-10
EP1150728A1 (en) 2001-11-07
US6991624B2 (en) 2006-01-31
CA2362051C (en) 2010-06-29

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FGA Letters patent sealed or granted (standard patent)