AU763868B2 - Method for the treatment of diseases or disorders of the inner ear - Google Patents

Method for the treatment of diseases or disorders of the inner ear Download PDF

Info

Publication number
AU763868B2
AU763868B2 AU29281/99A AU2928199A AU763868B2 AU 763868 B2 AU763868 B2 AU 763868B2 AU 29281/99 A AU29281/99 A AU 29281/99A AU 2928199 A AU2928199 A AU 2928199A AU 763868 B2 AU763868 B2 AU 763868B2
Authority
AU
Australia
Prior art keywords
inner ear
use according
nucleic acid
cells
active ingredient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU29281/99A
Other languages
English (en)
Other versions
AU2928199A (en
Inventor
Hubert Lowenheim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sound Pharmaceuticals Inc
Original Assignee
Otogene AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otogene AG filed Critical Otogene AG
Publication of AU2928199A publication Critical patent/AU2928199A/en
Application granted granted Critical
Publication of AU763868B2 publication Critical patent/AU763868B2/en
Assigned to SOUND PHARMACEUTICALS INCORPORATED reassignment SOUND PHARMACEUTICALS INCORPORATED Alteration of Name(s) in Register under S187 Assignors: OTOGENE AKTIENGESELLSCHAFT
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
AU29281/99A 1998-02-23 1999-02-23 Method for the treatment of diseases or disorders of the inner ear Ceased AU763868B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19807426A DE19807426A1 (de) 1998-02-23 1998-02-23 Verfahren zur Behandlung von Erkrankungen oder Störungen des Innenohrs
DE19807426 1998-02-23
PCT/EP1999/001153 WO1999042088A2 (de) 1998-02-23 1999-02-23 Verfahren zur behandlung von erkrankungen oder störungen des innenohrs

Publications (2)

Publication Number Publication Date
AU2928199A AU2928199A (en) 1999-09-06
AU763868B2 true AU763868B2 (en) 2003-07-31

Family

ID=7858563

Family Applications (1)

Application Number Title Priority Date Filing Date
AU29281/99A Ceased AU763868B2 (en) 1998-02-23 1999-02-23 Method for the treatment of diseases or disorders of the inner ear

Country Status (11)

Country Link
US (1) US7087581B1 (enExample)
EP (1) EP1056467B1 (enExample)
JP (1) JP2002503687A (enExample)
AT (1) ATE250936T1 (enExample)
AU (1) AU763868B2 (enExample)
CA (1) CA2320717C (enExample)
DE (2) DE19807426A1 (enExample)
DK (1) DK1056467T3 (enExample)
ES (1) ES2211055T3 (enExample)
PT (1) PT1056467E (enExample)
WO (1) WO1999042088A2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003530817A (ja) 1999-06-01 2003-10-21 ベイラー カレッジ オブ メディスン 聴覚障害、変形性関節症および細胞の異常増殖に関するａｔｏｎａｌ関連配列の治療用途のための組成物および方法
DE10027777A1 (de) * 2000-06-07 2001-12-13 Otogene Ag Transfektionsverfahren
EP1307542A2 (en) * 2000-07-11 2003-05-07 Sound Pharmaceuticals Incorporated Stimulation of cellular regeneration and differentiation in the inner ear
EP1547618B1 (en) 2002-10-02 2010-05-26 AnGes MG, Inc. Drug for auditory dysfunction
US20060148829A1 (en) * 2002-12-17 2006-07-06 Laurent Meijer Means for inducing differentiation of supernumerary hair cells and deiters' cells in the developing organ of corti
EP2293800B1 (en) 2008-06-06 2016-10-05 Quark Pharmaceuticals, Inc. Compositions and methods for treatment of ear disorders
DE102010007281A1 (de) 2010-02-08 2011-08-11 EMC microcollections GmbH, 72070 Neue Aminoalkyl-oxazol- und Aminoalkyl-thiazolcarbonsäureamide und ihre Anwendung zur Stimulation der endogenen situ Regeneration von Haarsinneszellen im Corti'schen Organ des Innenohres beim Säuger
RU2480195C1 (ru) * 2011-11-02 2013-04-27 Федеральное государственное учреждение "Российский научный центр восстановительной медицины и курортологии Федерального агентства по здравоохранению и социальному развитию РФ" (ФГУ "РНЦВМиК Росздрава РФ") Способ лечения заболеваний внутреннего уха
EP2802657B1 (en) 2012-01-12 2018-05-02 Quark Pharmaceuticals, Inc. Combination therapy for treating hearing and balance disorders
WO2013134022A1 (en) * 2012-03-05 2013-09-12 Wake Forest University Health Sciences Regeneration of inner ear cells
TWI710635B (zh) 2014-10-09 2020-11-21 美商珍維克公司 編碼人類無調同源物-1(hath1)之腺病毒載體

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19528388A1 (de) * 1995-08-02 1997-02-06 Hans Peter Prof Dr Med Zenner Verwendung von Adamantan-Derivaten zur Behandlung von Erkrankungen des Innenohrs
EP0866716A4 (en) * 1995-11-13 2002-05-02 Cambridge Neuroscience Inc METHOD FOR TREATING DISORDERS OF THE NON-VISUAL SENSORIC EPITHEL
US5962224A (en) * 1995-12-19 1999-10-05 Dana-Farber Cancer Institute Isolated DNA encoding p62 polypeptides and uses therefor
AU3591597A (en) 1996-06-28 1998-01-21 Regents Of The University Of California, The Transformation and genetherapy of cells of the inner ear
AU4600297A (en) * 1996-09-27 1998-04-17 Trustees Of The University Of Pennsylvania, The Novel methods for inducing proliferation in auditory receptor epithelium
US6043221A (en) 1997-07-30 2000-03-28 Amgen Inc. Method for preventing and treating hearing loss using a neuturin protein product

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
COATS ET AL. (1996) SCIENCE 272(5263):877-80 *
ST.CROIX ET AL. (1996) NATURE MEDICINE 2(11):1204-10 *

Also Published As

Publication number Publication date
DE19807426A1 (de) 1999-10-14
DK1056467T3 (da) 2004-02-09
DE59907195D1 (de) 2003-11-06
PT1056467E (pt) 2004-02-27
EP1056467A2 (de) 2000-12-06
AU2928199A (en) 1999-09-06
CA2320717A1 (en) 1999-08-26
WO1999042088A2 (de) 1999-08-26
EP1056467B1 (de) 2003-10-01
ES2211055T3 (es) 2004-07-01
CA2320717C (en) 2009-03-24
JP2002503687A (ja) 2002-02-05
WO1999042088A3 (de) 2000-03-02
ATE250936T1 (de) 2003-10-15
US7087581B1 (en) 2006-08-08

Similar Documents

Publication Publication Date Title
Rubel et al. A brief history of hair cell regeneration research and speculations on the future
Kole et al. Activating transcription factor 3 (ATF3) protects retinal ganglion cells and promotes functional preservation after optic nerve crush
Jacquin et al. Reorganization of pontine rhythmogenic neuronal networks in Krox-20 knockout mice
RU2288718C2 (ru) Лекарственные средства, содержащие ингибиторы человеческой h-sgk киназы, контролирующей клеточный объем
Geng et al. Electroacupuncture in the repair of spinal cord injury: inhibiting the Notch signaling pathway and promoting neural stem cell proliferation
Libertini The programmed aging paradigm: how we get old
AU763868B2 (en) Method for the treatment of diseases or disorders of the inner ear
Fjord-Larsen et al. Increased encapsulated cell biodelivery of nerve growth factor in the brain by transposon-mediated gene transfer
US20120195880A1 (en) Modulation of Synaptic Maintenance
PT2667715T (pt) Tratamento de perturbações do espetro do autismo utilizando o ácido glicil-l-2-metilpropil-l-glutâmico
Akil et al. Virally mediated overexpression of glial-derived neurotrophic factor elicits age-and dose-dependent neuronal toxicity and hearing loss
Idrizbegovic et al. Age-related increases in calcium-binding protein immunoreactivity in the cochlear nucleus of hearing impaired C57BL/6J mice
Melone et al. Huntington's disease: new frontiers for molecular and cell therapy
WO2021253078A1 (en) Process to produce photoreceptor cells
Liu et al. Potential effect of mechano growth factor E‐domain peptide on axonal guidance growth in primary cultured cortical neurons of rats
WO2024251289A1 (en) Use of kinase domain m7ck of trpm7 in preparation of drug for treating alzheimer's disease
O’Sullivan et al. ARS2 is required for retinal progenitor cell S-phase progression and Müller glial cell fate specification
CN111253492B (zh) 一种透脑性多肽及其在制备防治老年痴呆药物中应用
Crook et al. Surveying the landscape of Huntington's disease mechanisms, measurements, and medicines
Gao et al. The Administration of Circulating Extracellular Vesicles Modified by Anesthesia and Surgery Induces Delirium‐Like Behaviors in Aged Mice
Yao et al. Water deprivation increases the expression of neuronal nitric oxide synthase (nNOS) but not orexin‐A in the lateral hypothalamic area of the rat
Kelley Cellular commitment and differentiation in the cochlea: potential advances using gene transfer
Zhang et al. Functional optic tract rewiring via subtype-and target-specific axonal regeneration and presynaptic activity enhancement
Petrova et al. Protrudin functions as a scaffold in the endoplasmic reticulum to support axon regeneration in the adult central nervous system
PANE et al. The Upper Limb Cardiopulmonary Exercise Test in Friedrich Ataxia Patients

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
PC Assignment registered

Owner name: SOUND PHARMACEUTICALS INCORPORATED

Free format text: FORMER OWNER WAS: OTOGENE AKTIENGESELLSCHAFT