AU7526598A - 2-benzoyl-1,2,3,4-tetrahydroisoquinoline-3-carboxamide derivatives and the ir useas inhibitors of hepatic production of apob-100 - Google Patents

2-benzoyl-1,2,3,4-tetrahydroisoquinoline-3-carboxamide derivatives and the ir useas inhibitors of hepatic production of apob-100

Info

Publication number
AU7526598A
AU7526598A AU75265/98A AU7526598A AU7526598A AU 7526598 A AU7526598 A AU 7526598A AU 75265/98 A AU75265/98 A AU 75265/98A AU 7526598 A AU7526598 A AU 7526598A AU 7526598 A AU7526598 A AU 7526598A
Authority
AU
Australia
Prior art keywords
useas
apob
tetrahydroisoquinoline
benzoyl
inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU75265/98A
Other languages
English (en)
Inventor
Alain Claude-Marie Daugan
Pascal Maurice Charles Pianetti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of AU7526598A publication Critical patent/AU7526598A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU75265/98A 1997-04-22 1998-04-20 2-benzoyl-1,2,3,4-tetrahydroisoquinoline-3-carboxamide derivatives and the ir useas inhibitors of hepatic production of apob-100 Abandoned AU7526598A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9708119.4A GB9708119D0 (en) 1997-04-22 1997-04-22 Chemical compounds
GB9708119 1997-04-22
PCT/EP1998/002244 WO1998047877A1 (fr) 1997-04-22 1998-04-20 Derives 2-benzoyl-1,2,3,4-tetrahydro-isoquinoline-3-carboxamide et leur utilisation comme inhibiteurs de production hepatique de apob-100

Publications (1)

Publication Number Publication Date
AU7526598A true AU7526598A (en) 1998-11-13

Family

ID=10811155

Family Applications (1)

Application Number Title Priority Date Filing Date
AU75265/98A Abandoned AU7526598A (en) 1997-04-22 1998-04-20 2-benzoyl-1,2,3,4-tetrahydroisoquinoline-3-carboxamide derivatives and the ir useas inhibitors of hepatic production of apob-100

Country Status (6)

Country Link
AU (1) AU7526598A (fr)
GB (1) GB9708119D0 (fr)
HR (1) HRP980216A2 (fr)
MA (1) MA26483A1 (fr)
PE (1) PE68299A1 (fr)
WO (1) WO1998047877A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2206703A1 (fr) 2008-12-30 2010-07-14 Bayer CropScience AG Dérivés de pyrimidine et leur utilisation pour combattre la croissance indésirable de plantes
KR100962972B1 (ko) 2002-07-26 2010-06-09 주식회사유한양행 1-페닐피페리딘-3-온 유도체 및 그의 제조방법
US8124582B2 (en) * 2002-12-06 2012-02-28 Fibrogen, Inc. Treatment of diabetes
OA13024A (en) 2003-02-05 2006-11-10 Bayer Cropscience Gmbh Amino 1, 3, 5-triazines N-substituted with chiral bicyclic radicals, process for their preparation, compositions thereof and their use as herbicides and plant growth regulators.
WO2004096774A1 (fr) * 2003-05-01 2004-11-11 Glaxo Group Limited Derives d'acyle isoindoline et d'acyle isoquinoline utilises comme agents antiviraux
AU2018332887B2 (en) 2017-09-13 2022-12-08 Amgen Inc. Bisamide sarcomere activating compounds and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2146026A (en) * 1983-09-07 1985-04-11 Tanabe Seiyaku Co Peptides and process for preparing the same
DK160991C (da) * 1984-05-03 1991-11-11 Glaxo Group Ltd 5,14-dihydrobenzoe5,6aaisoindolooe2,1-baaisoquinolin-8,13-dionderivater, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende en saadan forbindelse
AU691201B2 (en) * 1993-11-01 1998-05-14 Japat Ltd. Endothelin receptor antagonists
WO1996040640A1 (fr) * 1995-06-07 1996-12-19 Pfizer Inc. DERIVES DE BIPHENYL-2-ACIDE CARBOXYLIQUE-TETRAHYDRO-ISOQUINOLEINE-6-YL AMIDES, PREPARATION DE CES AMIDES ET UTILISATION EN TANT QU'INHIBITEURS DE LA PROTEINE DE TRANSFERT DE TRIGLYCERIDE MICROSOMAL ET/OU DE LA SECRETION D'APOLIPOPROTEINES B (Apo B)
FR2748026B1 (fr) * 1996-04-26 1998-06-05 Adir Nouveaux inhibiteurs de metalloproteases, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
HRP980216A2 (en) 1998-12-31
WO1998047877A1 (fr) 1998-10-29
GB9708119D0 (en) 1997-06-11
MA26483A1 (fr) 2004-12-20
PE68299A1 (es) 1999-07-22

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase