AU7460194A - 2-phenylpyrrole derivatives as dopamine d3 receptor antagonists - Google Patents

2-phenylpyrrole derivatives as dopamine d3 receptor antagonists

Info

Publication number
AU7460194A
AU7460194A AU74601/94A AU7460194A AU7460194A AU 7460194 A AU7460194 A AU 7460194A AU 74601/94 A AU74601/94 A AU 74601/94A AU 7460194 A AU7460194 A AU 7460194A AU 7460194 A AU7460194 A AU 7460194A
Authority
AU
Australia
Prior art keywords
dopamine
receptor antagonists
phenylpyrrole derivatives
phenylpyrrole
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU74601/94A
Inventor
Christopher Norbert Johnson
Geoffrey Stemp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Publication of AU7460194A publication Critical patent/AU7460194A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU74601/94A 1993-07-30 1994-07-21 2-phenylpyrrole derivatives as dopamine d3 receptor antagonists Abandoned AU7460194A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9315801 1993-07-30
GB939315801A GB9315801D0 (en) 1993-07-30 1993-07-30 Compounds
PCT/EP1994/002412 WO1995004039A1 (en) 1993-07-30 1994-07-21 2-phenylpyrrole derivatives as dopamine d3 receptor antagonists

Publications (1)

Publication Number Publication Date
AU7460194A true AU7460194A (en) 1995-02-28

Family

ID=10739701

Family Applications (1)

Application Number Title Priority Date Filing Date
AU74601/94A Abandoned AU7460194A (en) 1993-07-30 1994-07-21 2-phenylpyrrole derivatives as dopamine d3 receptor antagonists

Country Status (7)

Country Link
US (1) US5637609A (en)
EP (1) EP0711279A1 (en)
JP (1) JPH09500882A (en)
AU (1) AU7460194A (en)
GB (1) GB9315801D0 (en)
WO (1) WO1995004039A1 (en)
ZA (1) ZA945589B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9402197D0 (en) * 1994-02-04 1994-03-30 Smithkline Beecham Plc Compounds
WO1996030333A1 (en) * 1995-03-27 1996-10-03 Smithkline Beecham Plc Bicyclic amine derivatives and their use as anti-psychotic agents
GB9512129D0 (en) * 1995-06-15 1995-08-16 Smithkline Beecham Plc Compounds
GB9810876D0 (en) 1998-05-20 1998-07-22 Smithkline Beecham Plc Compounds
AR023681A1 (en) 1998-10-08 2002-09-04 Smithkline Beecham Plc DERIVATIVES OF TETRAHYDROBENZAZEPINAS, PHARMACEUTICAL COMPOSITIONS AND THE USE OF THE SAME FOR THE MANUFACTURE OF A MEDICINAL PRODUCT.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK93087A (en) * 1986-02-27 1987-08-28 Duphar Int Res UNKNOWN ARYL SUBSTITUTED (N-PIPERIDINYL) METHYL AND (N-PIPERAZINYL) METHYLAZOLES WITH ANTIPYCOTIC PROPERTIES
PH23898A (en) * 1986-09-12 1989-12-18 Duphar Int Res New phenyl pyrrolidin-2-yl substituted-2-yl substituted 5-ring heterocycles having antipsycotic properties
AU4704593A (en) * 1992-08-06 1994-03-03 Smithkline Beecham Plc 5-(2-oxyphenyl)-pyrrole derivatives as dopamine d3 receptor antagonists

Also Published As

Publication number Publication date
EP0711279A1 (en) 1996-05-15
US5637609A (en) 1997-06-10
JPH09500882A (en) 1997-01-28
ZA945589B (en) 1996-01-29
WO1995004039A1 (en) 1995-02-09
GB9315801D0 (en) 1993-09-15

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