AU2759892A - N-aryl-n1-azabicyclo-ureas as 5-ht3 antagonists - Google Patents

N-aryl-n1-azabicyclo-ureas as 5-ht3 antagonists

Info

Publication number
AU2759892A
AU2759892A AU27598/92A AU2759892A AU2759892A AU 2759892 A AU2759892 A AU 2759892A AU 27598/92 A AU27598/92 A AU 27598/92A AU 2759892 A AU2759892 A AU 2759892A AU 2759892 A AU2759892 A AU 2759892A
Authority
AU
Australia
Prior art keywords
azabicyclo
ureas
antagonists
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU27598/92A
Inventor
Laramie Mary Gaster
Francis David King
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Publication of AU2759892A publication Critical patent/AU2759892A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU27598/92A 1991-10-15 1992-10-13 N-aryl-n1-azabicyclo-ureas as 5-ht3 antagonists Abandoned AU2759892A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9121835 1991-10-15
GB919121835A GB9121835D0 (en) 1991-10-15 1991-10-15 Pharmaceuticals

Publications (1)

Publication Number Publication Date
AU2759892A true AU2759892A (en) 1993-05-21

Family

ID=10702940

Family Applications (1)

Application Number Title Priority Date Filing Date
AU27598/92A Abandoned AU2759892A (en) 1991-10-15 1992-10-13 N-aryl-n1-azabicyclo-ureas as 5-ht3 antagonists

Country Status (3)

Country Link
AU (1) AU2759892A (en)
GB (1) GB9121835D0 (en)
WO (1) WO1993008185A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU654082B2 (en) * 1992-03-26 1994-10-20 Boehringer Ingelheim Italia S.P.A. Crystalline monohydrates of azabicyclo-1H-benzimidozole-1- carboxamides, the preparation and use thereof

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997034892A1 (en) * 1996-03-20 1997-09-25 Wake Forest University Sigma-2 receptors as biomarkers of tumor cell proliferation
AU2001255734A1 (en) 2000-04-27 2001-11-07 Wake Forest University Sigma-2 receptors as biomarkers of tumor cell proliferation
MXPA03000145A (en) * 2002-01-07 2003-07-15 Pfizer Oxo or oxy-pyridine compounds as 5-ht4 receptor modulators.
GB0211230D0 (en) 2002-05-16 2002-06-26 Medinnova Sf Treatment of heart failure
EP1543000B1 (en) 2002-09-25 2013-03-06 Memory Pharmaceuticals Corporation Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof
EP1697378B1 (en) 2003-12-22 2007-11-21 Memory Pharmaceuticals Corporation Indoles, 1h-indazoles, 1,2-benzisoxazoles, and 1,2-benzisothiazoles, and preparation and uses thereof
CN103724343A (en) 2004-03-25 2014-04-16 记忆药物公司 Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and uses thereof
WO2006001894A1 (en) 2004-04-22 2006-01-05 Memory Pharmaceutical Corporation Indoles, 1h-indazoles, 1,2-benzisoxazoles, 1,2-benzoisothiazoles, and preparation and uses thereof
AU2005243147A1 (en) 2004-05-07 2005-11-24 Memory Pharmaceuticals Corporation 1H-indazoles, benzothiazoles, 1,2-benzoisoxazoles, 1,2-benzoisothiazoles, and chromones and preparation and uses thereof
AU2005254800B2 (en) 2004-06-15 2010-12-09 Pfizer Inc. Benzimidazolone carboxylic acid derivatives
US7737163B2 (en) 2004-06-15 2010-06-15 Pfizer Inc. Benzimidazolone carboxylic acid derivatives
DE602005019094D1 (en) 2004-12-22 2010-03-11 Memory Pharmaceutical Corp NICOTINE ALPHA-7 RECEPTOR LIGANDS AGAINST DISEASES OF THE CNS
US8106066B2 (en) 2005-09-23 2012-01-31 Memory Pharmaceuticals Corporation Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof
EP2227556B1 (en) 2007-11-19 2014-08-27 Celera Corporation Lung cancer markers and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0235878A3 (en) * 1986-01-16 1989-06-14 Beecham Group Plc Novel compounds
IL87674A (en) * 1987-09-08 1993-08-18 Lilly Co Eli Azabicycloalkyl esters and amides of heterocyclic acids, their preparation and pharmaceutical compositions containing them
AU611976B2 (en) * 1987-12-24 1991-06-27 John Wyeth & Brother Limited Aroyl urea and carbamic acid derivatives of azabicyclo compounds
DE69026759D1 (en) * 1989-07-03 1996-06-05 Yoshitomi Pharmaceutical Benzazine compounds and their pharmaceutical uses
DK443489D0 (en) * 1989-09-08 1989-09-08 Ferrosan As SUBSTITUTED URINARY COMPOUNDS, THEIR PREPARATION AND USE
US4935511A (en) * 1989-09-26 1990-06-19 Rorer Pharmaceutical Corporation Benzoxazine and benzoxazepine carboxamide 5-HT3 antagonists

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU654082B2 (en) * 1992-03-26 1994-10-20 Boehringer Ingelheim Italia S.P.A. Crystalline monohydrates of azabicyclo-1H-benzimidozole-1- carboxamides, the preparation and use thereof

Also Published As

Publication number Publication date
GB9121835D0 (en) 1991-11-27
WO1993008185A1 (en) 1993-04-29

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