AU743586B2 - Use of equilenin as an antioxidant - Google Patents

Use of equilenin as an antioxidant Download PDF

Info

Publication number
AU743586B2
AU743586B2 AU53707/98A AU5370798A AU743586B2 AU 743586 B2 AU743586 B2 AU 743586B2 AU 53707/98 A AU53707/98 A AU 53707/98A AU 5370798 A AU5370798 A AU 5370798A AU 743586 B2 AU743586 B2 AU 743586B2
Authority
AU
Australia
Prior art keywords
equilenin
pharmaceutically acceptable
acceptable salt
disease
blood concentration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU53707/98A
Other languages
English (en)
Other versions
AU5370798A (en
Inventor
Steven Jay Adelman
Dorothy Helen Prozialeck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Products Corp filed Critical American Home Products Corp
Publication of AU5370798A publication Critical patent/AU5370798A/en
Application granted granted Critical
Publication of AU743586B2 publication Critical patent/AU743586B2/en
Assigned to WYETH reassignment WYETH Request to Amend Deed and Register Assignors: AMERICAN HOME PRODUCTS CORPORATION
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/566—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol having an oxo group in position 17, e.g. estrone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU53707/98A 1996-12-10 1997-12-05 Use of equilenin as an antioxidant Ceased AU743586B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US76257996A 1996-12-10 1996-12-10
US08/762579 1996-12-10
PCT/US1997/022154 WO1998025626A1 (fr) 1996-12-10 1997-12-05 Utilisation de l'equilenine comme antioxydant

Publications (2)

Publication Number Publication Date
AU5370798A AU5370798A (en) 1998-07-03
AU743586B2 true AU743586B2 (en) 2002-01-31

Family

ID=25065472

Family Applications (1)

Application Number Title Priority Date Filing Date
AU53707/98A Ceased AU743586B2 (en) 1996-12-10 1997-12-05 Use of equilenin as an antioxidant

Country Status (14)

Country Link
EP (1) EP0944391A1 (fr)
JP (1) JP2001506628A (fr)
KR (1) KR20000069412A (fr)
CN (1) CN1239892A (fr)
AR (1) AR010344A1 (fr)
AU (1) AU743586B2 (fr)
BR (1) BR9714384A (fr)
CA (1) CA2272087A1 (fr)
HU (1) HUP0000569A3 (fr)
IL (1) IL130071A0 (fr)
NZ (1) NZ336343A (fr)
TW (1) TW466115B (fr)
WO (1) WO1998025626A1 (fr)
ZA (1) ZA9711052B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6271221B1 (en) * 1996-12-10 2001-08-07 American Home Products Corporation Use of equilenin as an antioxidant
DE19915576A1 (de) * 1999-03-30 2000-10-05 Jenapharm Gmbh Equileninderivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
US20030139458A1 (en) * 2001-12-10 2003-07-24 Yansheng Du Treatment of neurodegenerative and cardiovascular disorders
CN108958639B (zh) 2017-05-19 2021-07-06 华邦电子股份有限公司 快闪存储器存储装置

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4937238A (en) * 1986-03-04 1990-06-26 The Board Of Regents Of The University Of Nebraska Prevention of mammary carcinoma
US5545635A (en) * 1995-05-23 1996-08-13 Eli Lilly And Company Inhibiting bone loss with equilenin

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4154820A (en) * 1976-02-23 1979-05-15 Akzona Incorporated Compositions containing alkali metal sulfate salts of conjugated estrogens and antioxidants as stabilizers
EP0240717A3 (fr) * 1986-03-04 1990-05-16 Board of Regents of the University of Nebraska Prévention du carcinome du sein

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4937238A (en) * 1986-03-04 1990-06-26 The Board Of Regents Of The University Of Nebraska Prevention of mammary carcinoma
US5545635A (en) * 1995-05-23 1996-08-13 Eli Lilly And Company Inhibiting bone loss with equilenin

Also Published As

Publication number Publication date
WO1998025626A1 (fr) 1998-06-18
TW466115B (en) 2001-12-01
AU5370798A (en) 1998-07-03
EP0944391A1 (fr) 1999-09-29
NZ336343A (en) 2000-11-24
JP2001506628A (ja) 2001-05-22
KR20000069412A (ko) 2000-11-25
CN1239892A (zh) 1999-12-29
CA2272087A1 (fr) 1998-06-18
IL130071A0 (en) 2000-02-29
HUP0000569A3 (en) 2000-11-28
ZA9711052B (en) 1999-06-09
AR010344A1 (es) 2000-06-07
BR9714384A (pt) 2000-05-16
HUP0000569A2 (hu) 2000-10-28

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
HB Alteration of name in register

Owner name: WYETH

Free format text: FORMER NAME WAS: AMERICAN HOME PRODUCTS CORPORATION