AU742488B2 - Levobupivacaine and its use - Google Patents

Levobupivacaine and its use Download PDF

Info

Publication number
AU742488B2
AU742488B2 AU84527/98A AU8452798A AU742488B2 AU 742488 B2 AU742488 B2 AU 742488B2 AU 84527/98 A AU84527/98 A AU 84527/98A AU 8452798 A AU8452798 A AU 8452798A AU 742488 B2 AU742488 B2 AU 742488B2
Authority
AU
Australia
Prior art keywords
surgery
levobupivacaine
block
motor block
hours
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU84527/98A
Other languages
English (en)
Other versions
AU8452798A (en
Inventor
Ian Ashley Evetts
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Darwin Discovery Ltd
Original Assignee
Darwin Discovery Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9715322A external-priority patent/GB9715322D0/en
Priority claimed from GBGB9722023.0A external-priority patent/GB9722023D0/en
Application filed by Darwin Discovery Ltd filed Critical Darwin Discovery Ltd
Publication of AU8452798A publication Critical patent/AU8452798A/en
Application granted granted Critical
Publication of AU742488B2 publication Critical patent/AU742488B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0085—Brain, e.g. brain implants; Spinal cord
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
AU84527/98A 1997-07-21 1998-07-21 Levobupivacaine and its use Expired AU742488B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9715322 1997-07-21
GB9715322A GB9715322D0 (en) 1997-07-21 1997-07-21 Levobupivacaine and its use
GBGB9722023.0A GB9722023D0 (en) 1997-10-17 1997-10-17 Levobupivacaine and its use
GB9722023 1997-10-17
PCT/GB1998/002169 WO1999004771A2 (en) 1997-07-21 1998-07-21 Use of levobupivacaine

Publications (2)

Publication Number Publication Date
AU8452798A AU8452798A (en) 1999-02-16
AU742488B2 true AU742488B2 (en) 2002-01-03

Family

ID=26311915

Family Applications (1)

Application Number Title Priority Date Filing Date
AU84527/98A Expired AU742488B2 (en) 1997-07-21 1998-07-21 Levobupivacaine and its use

Country Status (7)

Country Link
US (1) US5945435A (https=)
EP (1) EP0998286A2 (https=)
JP (1) JP2001510794A (https=)
AU (1) AU742488B2 (https=)
BR (1) BR9802536A (https=)
CA (1) CA2294950C (https=)
WO (1) WO1999004771A2 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU752802C (en) 1997-11-14 2006-04-13 Pacira Pharmaceuticals, Inc. Production of multivesicular liposomes
IL140899A0 (en) 1998-07-17 2002-02-10 Skyepharma Inc Lipid/polymer containing pharmaceutical compositions and processes for the preparation thereof
US6520949B2 (en) * 2001-04-02 2003-02-18 Martin St. Germain Method and apparatus for administering fluid to animals subcutaneously
AU2002322024B2 (en) * 2001-05-31 2008-05-08 Pacira Pharmaceuticals, Inc. Encapsulation of nanosuspensions in liposomes and microspheres
US11033495B1 (en) 2021-01-22 2021-06-15 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US12151024B2 (en) 2021-01-22 2024-11-26 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11357727B1 (en) 2021-01-22 2022-06-14 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11278494B1 (en) 2021-01-22 2022-03-22 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
EP4415713A4 (en) 2021-10-14 2025-08-06 Pacira Pharmaceuticals Inc MULTIVESICULAR LIPOSOME FORMULATIONS OF BUPIVACAINE AND THEIR USES
CN119677554A (zh) 2022-05-05 2025-03-21 普络夫有限责任公司 麻醉神经阻滞和方法
US12070454B1 (en) 2022-05-05 2024-08-27 Pfof Llc Anesthetic nerve block and method
US12251472B1 (en) 2024-05-20 2025-03-18 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US12156940B1 (en) 2024-05-20 2024-12-03 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US12280149B1 (en) 2024-05-20 2025-04-22 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4695576A (en) * 1984-07-09 1987-09-22 Astra Lake Medel Aktiebolag L-N-n-propylpipecolic acid-2,6-xylidide
SE9302218D0 (sv) * 1993-06-28 1993-06-28 Ab Astra New use
EP0727210B1 (en) * 1993-10-13 2001-12-19 Darwin Discovery Limited Analgesic agent and its use
AU704806B2 (en) * 1995-04-13 1999-05-06 Darwin Discovery Limited Levobupivacaine and its use as an anaesthetic in pregnant women
GB9704352D0 (en) * 1997-03-03 1997-04-23 Chiroscience Ltd Levobupivacaine and its use

Also Published As

Publication number Publication date
WO1999004771A3 (en) 1999-04-08
CA2294950A1 (en) 1999-02-04
CA2294950C (en) 2009-04-07
JP2001510794A (ja) 2001-08-07
EP0998286A2 (en) 2000-05-10
BR9802536A (pt) 1999-07-20
WO1999004771A2 (en) 1999-02-04
AU8452798A (en) 1999-02-16
US5945435A (en) 1999-08-31

Similar Documents

Publication Publication Date Title
AU742488B2 (en) Levobupivacaine and its use
KR20190060007A (ko) 덱스메데토미딘 경피 전달 장치를 이용한 통증을 관리하는 방법
Dauri et al. Continuous femoral nerve block provides superior analgesia compared with continuous intra-articular and wound infusion after anterior cruciate ligament reconstruction
Bathari et al. A randomised trial to compare the effect of addition of clonidine or fentanyl to hyperbaric ropivacaine for spinal anaesthesia for knee arthroscopy
Gurbet et al. Combination of ultra-low dose bupivacaine and fentanyl for spinal anaesthesia in out-patient anorectal surgery
Panigrahi et al. High dose dexamethasone offers better postoperative analgesia than dexmedetomidine when added to intra articular ropivacaine following knee arthroscopic surgery
Reddy et al. Comparison of efficacy of butorphanol and fentanyl as intrathecal adjuvant to bupivacaine
Dimopoulou et al. Effect of intrafragmentary bupivacaine (haematoma block) on analgesic requirements in dogs undergoing fracture repair
Raval et al. A clinical comparative study between dexmedetomidine v/s clonidine with bupivacaine intrathecally in major orthopaedic lower limb surgery
Abdelzaam et al. A comparative study of intrathecal injection of bupivacaine alone or with fentanyl, clonidine, and neostigmine in lower abdominal surgeries
Prajwal et al. Comparison of efficacy and safety of intrathecal ropivacaine-fentanyl and bupivacaine-fentanyl in lower abdominal and lower limb surgeries
MXPA00000397A (es) Levobupivacaina y su uso
Gudaitytė et al. Spinal anaesthesia with 4 mg versus 3 mg of hyperbaric bupivacaine plus 10 µg of fentanyl for adult anorectal surgery: faster recovery with prolonged analgesia
Suryasree et al. Evaluation of Effect of Low Dose Fentanyl, Dexmedetomidine and Clonidine in Spinal Anesthesia in Hysterectomies and Lower Abdominal Surgeries
Ahmad et al. COMPARATIVE EVALUATION OF CLONIDINE VERSUS TRAMADOL AS ADJUVANT TO EPIDURAL ANAESTHESIA WITH 0.5% BUPIVACAINE FOR LOWER LIMB ORTHOPEDIC PROCEDURES
Chandra et al. Comparison of Bupivacaine (0.5%) and Bupivacaine (0.5%) with Dexmedetomide for Spinal Anesthesia in Lower Abdominal and Pelvic Surgery.
Gupta et al. COMPARISON OF BUPIVACAINE AND BUPIVACAINE WITH FENTANYL IN INTRATHECAL BLOCKS FOR CYSTOSCOPIC UROLOGICAL PROCEDURES
Mandal et al. A Comparative Study of Intrathecal 0.5% Isobaric Ropivacaine Vs 0.5% Isobaric Bupivacaine in Lower Abdominal Surgeries.
Suntan et al. Comparison of the efficacy of dexmedetomidine and fentanyl as adjuvants to bupivacaine in arthroscopic knee surgeries.
Nithyashree et al. A Comparative Study of Intrathecal Hyperbaric Bupivacaine 0.5% with Fentanyl versus Hyperbaric Bupivacaine 0.5% with Buprenorphine in Lower Limb and Lower Abdominal Surgeries.
Geetha et al. A comparative study of 0.75% ropivacaine and 0.5% bupivacaine for epidural anesthesia in patients undergoing lower abdominal and lower extremity surgeries
Zekry et al. Ketamine versus dexamethasone as an adjuvant to local anesthetics in combined sciatic-femoral nerve block for below knee surgeries
Agrawal et al. A Comparison of the Intrathecal Isobaric 0.5% Levobupivacaine with Fentanyl and Isobaric 0.5% Ropivacaine with Fentanyl for Lower Abdominal and Lower Limb Surgeries: A Prospective Randomised Double Blind Controlled Study.
Elfawal et al. Comparative study of intrathecal midazolam versus fentanyl as adjuvants to ropivacaine for lower-limb surgery.
CA et al. Comparision of Buprenorphine versus Butorphanol as an adjuvant to intrathecal hyperbaric bupivacaine for elective infraumbilical surgeries: A randomised control study at a tertiary care hospital, Mandya

Legal Events

Date Code Title Description
TH Corrigenda

Free format text: IN VOL. 13, NO 19, PAGE(S) 2820-2824 UNDER THE HEADING APPLICATIONS LAPSED, REFUSED OR WITHDRAWN PLEASE DELETE ALL REFERENCE TO APPLICATION NO. 83632/98, 84527/98 AND 84645/98

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired