AU741766B2 - Thrombin inhibitors - Google Patents

Thrombin inhibitors Download PDF

Info

Publication number
AU741766B2
AU741766B2 AU15395/99A AU1539599A AU741766B2 AU 741766 B2 AU741766 B2 AU 741766B2 AU 15395/99 A AU15395/99 A AU 15395/99A AU 1539599 A AU1539599 A AU 1539599A AU 741766 B2 AU741766 B2 AU 741766B2
Authority
AU
Australia
Prior art keywords
blood
compound
mammal
inhibiting
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU15395/99A
Other languages
English (en)
Other versions
AU1539599A (en
Inventor
Craig Coburn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9809784.3A external-priority patent/GB9809784D0/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of AU1539599A publication Critical patent/AU1539599A/en
Application granted granted Critical
Publication of AU741766B2 publication Critical patent/AU741766B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
AU15395/99A 1997-12-01 1998-11-25 Thrombin inhibitors Ceased AU741766B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US6709697P 1997-12-01 1997-12-01
US60/067096 1997-12-01
GB9809784 1998-05-07
GBGB9809784.3A GB9809784D0 (en) 1998-05-07 1998-05-07 Thrombin Inhibitors
PCT/US1998/025362 WO1999027930A1 (en) 1997-12-01 1998-11-25 Thrombin inhibitors

Publications (2)

Publication Number Publication Date
AU1539599A AU1539599A (en) 1999-06-16
AU741766B2 true AU741766B2 (en) 2001-12-06

Family

ID=26313616

Family Applications (1)

Application Number Title Priority Date Filing Date
AU15395/99A Ceased AU741766B2 (en) 1997-12-01 1998-11-25 Thrombin inhibitors

Country Status (5)

Country Link
EP (1) EP1039907A4 (ja)
JP (1) JP2001524522A (ja)
AU (1) AU741766B2 (ja)
CA (1) CA2309347A1 (ja)
WO (1) WO1999027930A1 (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6610692B1 (en) * 1998-10-30 2003-08-26 Merck & Co., Inc. Thrombin inhibitors
DE19900471A1 (de) * 1999-01-08 2000-07-13 Merck Patent Gmbh Imidazo[4,5c]-pyridin-4-on-derivate
IL277071B1 (en) 2018-03-08 2024-03-01 Incyte Corp Aminopyrizine diol compounds as PI3K–y inhibitors
US11046658B2 (en) 2018-07-02 2021-06-29 Incyte Corporation Aminopyrazine derivatives as PI3K-γ inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5658930A (en) * 1994-12-13 1997-08-19 Corvas International, Inc. Aromatic heterocyclic derivatives as enzyme inhibitors
WO1997001338A1 (en) * 1995-06-27 1997-01-16 Merck & Co., Inc. Pyridinone-thrombin inhibitors
CA2245811A1 (en) * 1996-02-22 1997-08-28 Merck & Co., Inc. Pyridinone thrombin inhibitors

Also Published As

Publication number Publication date
WO1999027930A1 (en) 1999-06-10
AU1539599A (en) 1999-06-16
EP1039907A1 (en) 2000-10-04
CA2309347A1 (en) 1999-06-10
JP2001524522A (ja) 2001-12-04
EP1039907A4 (en) 2001-09-19

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired