AU738348B2 - Platelet suspensions and methods for resuspending platelets - Google Patents
Platelet suspensions and methods for resuspending platelets Download PDFInfo
- Publication number
- AU738348B2 AU738348B2 AU73896/98A AU7389698A AU738348B2 AU 738348 B2 AU738348 B2 AU 738348B2 AU 73896/98 A AU73896/98 A AU 73896/98A AU 7389698 A AU7389698 A AU 7389698A AU 738348 B2 AU738348 B2 AU 738348B2
- Authority
- AU
- Australia
- Prior art keywords
- platelet
- platelets
- plasma
- accordance
- solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title claims description 27
- 239000000725 suspension Substances 0.000 title claims description 21
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 52
- 239000003634 thrombocyte concentrate Substances 0.000 claims description 44
- 210000002381 plasma Anatomy 0.000 claims description 43
- 235000002639 sodium chloride Nutrition 0.000 claims description 27
- 239000011780 sodium chloride Substances 0.000 claims description 26
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims description 20
- 210000004623 platelet-rich plasma Anatomy 0.000 claims description 12
- 239000001103 potassium chloride Substances 0.000 claims description 10
- 235000011164 potassium chloride Nutrition 0.000 claims description 10
- 235000015097 nutrients Nutrition 0.000 claims description 5
- VMHLLURERBWHNL-UHFFFAOYSA-M Sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 claims description 3
- 150000003841 chloride salts Chemical class 0.000 claims description 3
- 239000001632 sodium acetate Substances 0.000 claims description 3
- 235000017281 sodium acetate Nutrition 0.000 claims description 3
- 239000001509 sodium citrate Substances 0.000 claims description 3
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims description 3
- 210000001772 blood platelet Anatomy 0.000 description 97
- 239000000243 solution Substances 0.000 description 26
- 210000004369 blood Anatomy 0.000 description 16
- 239000008280 blood Substances 0.000 description 16
- 239000000306 component Substances 0.000 description 10
- 239000012266 salt solution Substances 0.000 description 10
- 239000012085 test solution Substances 0.000 description 8
- 238000000926 separation method Methods 0.000 description 7
- XSDQTOBWRPYKKA-UHFFFAOYSA-N amiloride Chemical compound NC(=N)NC(=O)C1=NC(Cl)=C(N)N=C1N XSDQTOBWRPYKKA-UHFFFAOYSA-N 0.000 description 6
- 229960002576 amiloride Drugs 0.000 description 6
- 210000004027 cell Anatomy 0.000 description 6
- 239000008188 pellet Substances 0.000 description 5
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 description 4
- 210000003743 erythrocyte Anatomy 0.000 description 4
- 210000000265 leukocyte Anatomy 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 3
- 239000000654 additive Substances 0.000 description 3
- 230000000996 additive effect Effects 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- 108091006629 SLC13A2 Proteins 0.000 description 2
- 238000002835 absorbance Methods 0.000 description 2
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 description 2
- 210000000601 blood cell Anatomy 0.000 description 2
- 230000001413 cellular effect Effects 0.000 description 2
- 239000000470 constituent Substances 0.000 description 2
- 239000000819 hypertonic solution Substances 0.000 description 2
- 229940021223 hypertonic solution Drugs 0.000 description 2
- 229910001629 magnesium chloride Inorganic materials 0.000 description 2
- 230000003204 osmotic effect Effects 0.000 description 2
- 235000011083 sodium citrates Nutrition 0.000 description 2
- 238000009987 spinning Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 239000005528 B01AC05 - Ticlopidine Substances 0.000 description 1
- 239000002126 C01EB10 - Adenosine Substances 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 229960005305 adenosine Drugs 0.000 description 1
- 239000012503 blood component Substances 0.000 description 1
- -1 but not limited to Substances 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 229940061607 dibasic sodium phosphate Drugs 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 description 1
- XEYBHCRIKKKOSS-UHFFFAOYSA-N disodium;azanylidyneoxidanium;iron(2+);pentacyanide Chemical compound [Na+].[Na+].[Fe+2].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].[O+]#N XEYBHCRIKKKOSS-UHFFFAOYSA-N 0.000 description 1
- 239000012636 effector Substances 0.000 description 1
- 230000005714 functional activity Effects 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 239000000644 isotonic solution Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 229940045641 monobasic sodium phosphate Drugs 0.000 description 1
- 229910000403 monosodium phosphate Inorganic materials 0.000 description 1
- 235000019799 monosodium phosphate Nutrition 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 235000021317 phosphate Nutrition 0.000 description 1
- 239000002953 phosphate buffered saline Substances 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 229960004249 sodium acetate Drugs 0.000 description 1
- 229960002668 sodium chloride Drugs 0.000 description 1
- 229960001790 sodium citrate Drugs 0.000 description 1
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
- 229940083618 sodium nitroprusside Drugs 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- PHWBOXQYWZNQIN-UHFFFAOYSA-N ticlopidine Chemical compound ClC1=CC=CC=C1CN1CC(C=CS2)=C2CC1 PHWBOXQYWZNQIN-UHFFFAOYSA-N 0.000 description 1
- 229960005001 ticlopidine Drugs 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Dentistry (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- External Artificial Organs (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/871,115 US6063624A (en) | 1997-06-09 | 1997-06-09 | Platelet suspensions and methods for resuspending platelets |
| US08/871115 | 1997-06-09 | ||
| PCT/US1998/010029 WO1998056247A1 (en) | 1997-06-09 | 1998-05-15 | Platelet suspensions and methods for resuspending platelets |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU7389698A AU7389698A (en) | 1998-12-30 |
| AU738348B2 true AU738348B2 (en) | 2001-09-13 |
Family
ID=25356764
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU73896/98A Expired AU738348B2 (en) | 1997-06-09 | 1998-05-15 | Platelet suspensions and methods for resuspending platelets |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US6063624A (enExample) |
| EP (1) | EP1001675A4 (enExample) |
| JP (1) | JP2002503250A (enExample) |
| AU (1) | AU738348B2 (enExample) |
| BR (1) | BR9810088A (enExample) |
| CA (1) | CA2290389A1 (enExample) |
| WO (1) | WO1998056247A1 (enExample) |
Families Citing this family (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6063624A (en) * | 1997-06-09 | 2000-05-16 | Baxter International Inc. | Platelet suspensions and methods for resuspending platelets |
| US7498156B2 (en) * | 1998-07-21 | 2009-03-03 | Caridianbct Biotechnologies, Llc | Use of visible light at wavelengths of 500 to 550 nm to reduce the number of pathogens in blood and blood components |
| US7049110B2 (en) | 1998-07-21 | 2006-05-23 | Gambro, Inc. | Inactivation of West Nile virus and malaria using photosensitizers |
| US7220747B2 (en) | 1999-07-20 | 2007-05-22 | Gambro, Inc. | Method for preventing damage to or rejuvenating a cellular blood component using mitochondrial enhancer |
| TW590780B (en) | 2000-06-02 | 2004-06-11 | Gambro Inc | Additive solutions containing riboflavin |
| US7648699B2 (en) | 2000-06-02 | 2010-01-19 | Caridianbct Biotechnologies, Llc | Preventing transfusion related complications in a recipient of a blood transfusion |
| US7985588B2 (en) | 2000-06-02 | 2011-07-26 | Caridianbct Biotechnologies, Llc | Induction of and maintenance of nucleic acid damage in pathogens using riboflavin and light |
| DE60109184T2 (de) * | 2000-10-16 | 2005-12-29 | Universite De Liege | Medizinische zusammensetzung und insbesondere seine verwendung in der flüssigkeitstherapie |
| US6548241B1 (en) | 2000-11-28 | 2003-04-15 | Gambro, Inc. | Storage solution containing photosensitizer for inactivation of biological contaminants |
| US7011852B2 (en) * | 2001-05-07 | 2006-03-14 | Hemogenesis, Llc | Separation of platelets from whole blood for use as a healant |
| US8101077B2 (en) * | 2001-05-07 | 2012-01-24 | Sivaprasad Sukavaneshvar | Device for separating platelets from fluid suspensions |
| US7264608B2 (en) * | 2001-12-05 | 2007-09-04 | Fenwal, Inc. | Manual processing systems and methods for providing blood components conditioned for pathogen inactivation |
| JP2005523337A (ja) * | 2002-04-24 | 2005-08-04 | ガンブロ インコーポレーテッド | 病原体が減少する血液および血液構成成分のプロセスの間でのアデニンの除去 |
| US20030205538A1 (en) | 2002-05-03 | 2003-11-06 | Randel Dorian | Methods and apparatus for isolating platelets from blood |
| US7374678B2 (en) | 2002-05-24 | 2008-05-20 | Biomet Biologics, Inc. | Apparatus and method for separating and concentrating fluids containing multiple components |
| US7832566B2 (en) | 2002-05-24 | 2010-11-16 | Biomet Biologics, Llc | Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles |
| US6905612B2 (en) * | 2003-03-21 | 2005-06-14 | Hanuman Llc | Plasma concentrate apparatus and method |
| US7992725B2 (en) | 2002-05-03 | 2011-08-09 | Biomet Biologics, Llc | Buoy suspension fractionation system |
| US7553413B2 (en) * | 2005-02-07 | 2009-06-30 | Hanuman Llc | Plasma concentrator device |
| US20040182795A1 (en) * | 2003-03-21 | 2004-09-23 | Randel Dorian | Apparatus and method for concentration of plasma from whole blood |
| US7845499B2 (en) | 2002-05-24 | 2010-12-07 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
| WO2003099412A1 (en) | 2002-05-24 | 2003-12-04 | Biomet Manufacturing Corp. | Apparatus and method for separating and concentrating fluids containing multiple components |
| US20060278588A1 (en) | 2002-05-24 | 2006-12-14 | Woodell-May Jennifer E | Apparatus and method for separating and concentrating fluids containing multiple components |
| US20090023130A1 (en) * | 2003-02-28 | 2009-01-22 | Caridianbct Biotechnologies, Llc | Prevention of Transfusion Related Acute Lung Injury Using Riboflavin and Light |
| CA2524712A1 (en) * | 2003-06-20 | 2004-12-29 | Pall Corporation | Processing of platelet-containing biological fluids |
| CA2534685A1 (en) * | 2003-08-04 | 2005-02-17 | Human Biosystems | Preservation of blood cells |
| US20050137517A1 (en) * | 2003-12-19 | 2005-06-23 | Baxter International Inc. | Processing systems and methods for providing leukocyte-reduced blood components conditioned for pathogen inactivation |
| US7473678B2 (en) | 2004-10-14 | 2009-01-06 | Biomimetic Therapeutics, Inc. | Platelet-derived growth factor compositions and methods of use thereof |
| US7694828B2 (en) | 2005-04-27 | 2010-04-13 | Biomet Manufacturing Corp. | Method and apparatus for producing autologous clotting components |
| BRPI0618794A2 (pt) | 2005-11-17 | 2011-09-13 | Biomimetic Therapeutics Inc | uso de uma matriz biocompatìvel, kit e composição para aumento ósseo, especialmente para aumento do osso maxilofacial |
| EP2311505B1 (en) | 2006-02-09 | 2013-11-06 | BioMimetic Therapeutics, LLC | Compositions and methods for treating bone |
| US8567609B2 (en) | 2006-05-25 | 2013-10-29 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
| ES2664229T3 (es) | 2006-06-30 | 2018-04-18 | Biomimetic Therapeutics, Llc | Composiciones y métodos de biomatriz-PDGF para el tratamiento de lesiones del manguito rotador |
| US9161967B2 (en) | 2006-06-30 | 2015-10-20 | Biomimetic Therapeutics, Llc | Compositions and methods for treating the vertebral column |
| CA2595353C (en) * | 2006-07-31 | 2013-11-05 | Canadian Blood Services | Platelet additive solution |
| WO2008022651A1 (en) * | 2006-08-21 | 2008-02-28 | Antoine Turzi | Process and device for the preparation of platelet rich plasma for extemporaneous use and combination thereof with skin and bone cells |
| WO2008073628A2 (en) | 2006-11-03 | 2008-06-19 | Biomimetic Therapeutics, Inc. | Compositions and methods for arthrodetic procedures |
| US20080195476A1 (en) * | 2007-02-09 | 2008-08-14 | Marchese Michael A | Abandonment remarketing system |
| US7964339B2 (en) * | 2007-02-09 | 2011-06-21 | Canadian Blood Services | Cold storage of modified platelets |
| US8067151B2 (en) * | 2007-02-09 | 2011-11-29 | Canadian Blood Services | Cold storage of pegylated platelets at about or below 0° C. |
| US8328024B2 (en) | 2007-04-12 | 2012-12-11 | Hanuman, Llc | Buoy suspension fractionation system |
| US7806276B2 (en) | 2007-04-12 | 2010-10-05 | Hanuman, Llc | Buoy suspension fractionation system |
| WO2009018309A2 (en) * | 2007-08-01 | 2009-02-05 | Caridianbct Biotechnologies, Llc | Pathogen inactivation of whole blood |
| US8835104B2 (en) * | 2007-12-20 | 2014-09-16 | Fenwal, Inc. | Medium and methods for the storage of platelets |
| ES2422259T3 (es) | 2008-02-07 | 2013-09-10 | Biomimetic Therapeutics Inc | Composiciones para la osteogénesis por distracción |
| PL2259774T3 (pl) | 2008-02-27 | 2013-04-30 | Biomet Biologics Llc | Sposoby i kompozycje dla wprowadzania antagonisty receptora interleukiny-1 |
| JP4528863B2 (ja) * | 2008-02-29 | 2010-08-25 | ヘモネティクス・コーポレーション | アフェレーシス装置 |
| US8337711B2 (en) * | 2008-02-29 | 2012-12-25 | Biomet Biologics, Llc | System and process for separating a material |
| MX2011002555A (es) | 2008-09-09 | 2011-08-03 | Biomimetic Therapeutics Inc | Composiciones de factor de crecimiento derivadas de plaquetas y metodo para el tratamiento de lesiones de tendon y ligamentos. |
| WO2010039994A2 (en) * | 2008-10-01 | 2010-04-08 | Caridianbct, Inc. | Platelet additive solution for leukoreducing white blood cells in apheresed platelets |
| US8187475B2 (en) | 2009-03-06 | 2012-05-29 | Biomet Biologics, Llc | Method and apparatus for producing autologous thrombin |
| US8313954B2 (en) | 2009-04-03 | 2012-11-20 | Biomet Biologics, Llc | All-in-one means of separating blood components |
| US9011800B2 (en) | 2009-07-16 | 2015-04-21 | Biomet Biologics, Llc | Method and apparatus for separating biological materials |
| CN107080834A (zh) | 2010-02-22 | 2017-08-22 | 生物模拟治疗有限责任公司 | 用于治疗腱病的血小板衍生生长因子组合物和方法 |
| US8802363B2 (en) | 2010-04-08 | 2014-08-12 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Zeodration method for the preservation of blood platelets |
| US8591391B2 (en) | 2010-04-12 | 2013-11-26 | Biomet Biologics, Llc | Method and apparatus for separating a material |
| US11462321B2 (en) | 2010-08-12 | 2022-10-04 | Fenwal, Inc. | Mobile applications for blood centers |
| US8485828B2 (en) * | 2010-08-12 | 2013-07-16 | Fenwal, Inc. | Methods and systems for blood collection operator training |
| US11901069B2 (en) | 2010-08-12 | 2024-02-13 | Fenwal, Inc. | Processing blood donation data for presentation on operator interface |
| US9555171B2 (en) | 2010-09-30 | 2017-01-31 | Depuy Mitek, Llc | Methods and devices for collecting separate components of whole blood |
| WO2012139017A1 (en) | 2011-04-07 | 2012-10-11 | Fenwal, Inc. | Automated methods and systems for providing platelet concentrates with reduced residual plasma volumes and storage media for such platelet concentrates |
| EP2704760B1 (en) | 2011-05-03 | 2017-09-20 | Fenwal, Inc. | Platelet resuspension method and apparatus |
| EP2806914B1 (en) | 2012-01-23 | 2021-09-22 | Estar Technologies Ltd | A system and method for obtaining a cellular sample enriched with defined cells such as platelet rich plasma(prp) |
| CA2885721A1 (en) | 2012-07-11 | 2014-01-16 | Biomimetic Therapeutics, Llc | Cell-based assay for neutralizing antibodies |
| US9642956B2 (en) | 2012-08-27 | 2017-05-09 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
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| US10208095B2 (en) | 2013-03-15 | 2019-02-19 | Biomet Manufacturing, Llc | Methods for making cytokine compositions from tissues using non-centrifugal methods |
| US9895418B2 (en) | 2013-03-15 | 2018-02-20 | Biomet Biologics, Llc | Treatment of peripheral vascular disease using protein solutions |
| US9550028B2 (en) | 2014-05-06 | 2017-01-24 | Biomet Biologics, LLC. | Single step desiccating bead-in-syringe concentrating device |
| US12440835B2 (en) | 2019-01-21 | 2025-10-14 | Vias Partners, Llc | Methods, systems and apparatus for separating components of a biological sample |
| WO2021087222A1 (en) | 2019-10-31 | 2021-05-06 | Eclipse Medcorp, Llc | Systems, methods and apparatus for separating components of a sample |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE32874E (en) * | 1982-11-01 | 1989-02-21 | Gail A. Rock | Plasma-free medium for platelet storage |
| US5462752A (en) * | 1994-07-28 | 1995-10-31 | Prp, Inc. | Inhibition of platelet binding |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US32874A (en) * | 1861-07-23 | Electro-magnet | ||
| US4828976A (en) * | 1983-12-29 | 1989-05-09 | Thomas Jefferson University | Glucose free media for storing blood platelets |
| US5234918A (en) * | 1988-04-04 | 1993-08-10 | American Cyanamid Company | Certain phosphinyl-oxy-phenyl-methyl-pyridinium-hydroxide inner salts useful as antagonists of PAF |
| US5622867A (en) * | 1994-10-19 | 1997-04-22 | Lifecell Corporation | Prolonged preservation of blood platelets |
| US6063624A (en) * | 1997-06-09 | 2000-05-16 | Baxter International Inc. | Platelet suspensions and methods for resuspending platelets |
-
1997
- 1997-06-09 US US08/871,115 patent/US6063624A/en not_active Expired - Lifetime
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1998
- 1998-05-15 CA CA002290389A patent/CA2290389A1/en not_active Abandoned
- 1998-05-15 BR BR9810088-2A patent/BR9810088A/pt not_active IP Right Cessation
- 1998-05-15 WO PCT/US1998/010029 patent/WO1998056247A1/en not_active Ceased
- 1998-05-15 AU AU73896/98A patent/AU738348B2/en not_active Expired
- 1998-05-15 EP EP98921239A patent/EP1001675A4/en not_active Withdrawn
- 1998-05-15 JP JP50247199A patent/JP2002503250A/ja not_active Ceased
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2000
- 2000-01-24 US US09/490,191 patent/US6326197B1/en not_active Expired - Lifetime
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2001
- 2001-10-26 US US10/029,785 patent/US6613566B2/en not_active Expired - Lifetime
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE32874E (en) * | 1982-11-01 | 1989-02-21 | Gail A. Rock | Plasma-free medium for platelet storage |
| US5462752A (en) * | 1994-07-28 | 1995-10-31 | Prp, Inc. | Inhibition of platelet binding |
Non-Patent Citations (1)
| Title |
|---|
| GULLIKSSON, H ET AL ( 1993) TRANSFUSION 33(4) 301-303 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1001675A4 (en) | 2004-10-13 |
| BR9810088A (pt) | 2000-08-08 |
| JP2002503250A (ja) | 2002-01-29 |
| US6613566B2 (en) | 2003-09-02 |
| US20020110914A1 (en) | 2002-08-15 |
| WO1998056247A1 (en) | 1998-12-17 |
| US6326197B1 (en) | 2001-12-04 |
| EP1001675A1 (en) | 2000-05-24 |
| AU7389698A (en) | 1998-12-30 |
| US6063624A (en) | 2000-05-16 |
| CA2290389A1 (en) | 1998-12-17 |
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