AU7270794A - Succinamide derivatives, processes for their preparation and their use as gelatinase and collagenase inhibitors - Google Patents
Succinamide derivatives, processes for their preparation and their use as gelatinase and collagenase inhibitorsInfo
- Publication number
- AU7270794A AU7270794A AU72707/94A AU7270794A AU7270794A AU 7270794 A AU7270794 A AU 7270794A AU 72707/94 A AU72707/94 A AU 72707/94A AU 7270794 A AU7270794 A AU 7270794A AU 7270794 A AU7270794 A AU 7270794A
- Authority
- AU
- Australia
- Prior art keywords
- gelatinase
- processes
- preparation
- collagenase inhibitors
- succinamide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB939315965A GB9315965D0 (en) | 1993-08-02 | 1993-08-02 | Peptidyl derivatives |
GB9315965 | 1993-08-02 | ||
GB9400377 | 1994-01-11 | ||
GB9400377A GB9400377D0 (en) | 1994-01-11 | 1994-01-11 | Peptidyl derivatives |
PCT/GB1994/001697 WO1995004033A1 (en) | 1993-08-02 | 1994-08-02 | Succinamide derivatives, processes for their preparation and their use as gelatinase and collagenase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
AU7270794A true AU7270794A (en) | 1995-02-28 |
Family
ID=26303319
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU72707/94A Abandoned AU7270794A (en) | 1993-08-02 | 1994-08-02 | Succinamide derivatives, processes for their preparation and their use as gelatinase and collagenase inhibitors |
Country Status (6)
Country | Link |
---|---|
US (1) | US5827890A (de) |
EP (1) | EP0712390B1 (de) |
JP (1) | JPH09503492A (de) |
AU (1) | AU7270794A (de) |
DE (1) | DE69415159T2 (de) |
WO (1) | WO1995004033A1 (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9507799D0 (en) * | 1995-04-18 | 1995-05-31 | British Biotech Pharm | Metalloproteinase inhibitors |
HUP9903863A3 (en) | 1995-11-23 | 2000-11-28 | British Biotech Pharm | Metalloproteinase inhibitors |
TW448172B (en) * | 1996-03-08 | 2001-08-01 | Pharmacia & Upjohn Co Llc | Novel hydroxamic acid derivatives useful for the treatment of diseases related to connective tissue degradation |
US5830869A (en) * | 1996-06-21 | 1998-11-03 | Mitchell; Mark Allen | Thiadiazole amide MMP inhibitors |
US6462023B1 (en) | 1996-09-10 | 2002-10-08 | British Biotech Pharmaceuticals, Ltd. | Cytostatic agents |
GB2324528B (en) * | 1996-09-10 | 2000-07-26 | British Biotech Pharm | Cytostatic hydroxamic acid derivatives |
US5840974A (en) * | 1996-12-04 | 1998-11-24 | Britisch Biotech Pharmaceuticals, Ltd. | Metalloproteinase inhibitors |
US5847148A (en) * | 1997-04-10 | 1998-12-08 | Pharmacia & Upjohn Company | Thiadiazole derivatives useful for the treatment of diseases related to connective tissue degradation |
GB9803005D0 (en) * | 1998-02-12 | 1998-04-08 | British Biotech Pharm | Anti-inflammatory agents |
GB9804777D0 (en) * | 1998-03-07 | 1998-04-29 | British Biotech Pharm | Anti-inflammatory agents |
US6329418B1 (en) | 1998-04-14 | 2001-12-11 | The Procter & Gamble Company | Substituted pyrrolidine hydroxamate metalloprotease inhibitors |
US6696456B1 (en) | 1999-10-14 | 2004-02-24 | The Procter & Gamble Company | Beta disubstituted metalloprotease inhibitors |
RU2245876C2 (ru) * | 2000-03-21 | 2005-02-10 | Дзе Проктер Энд Гэмбл Компани | Производные сульфонамидов и фармацевтическая композиция на их основе |
AU2001245862A1 (en) * | 2000-03-21 | 2001-10-03 | The Procter & Gamble Company | Difluorobutyric acid metalloprotease inhibitors |
CA2403778A1 (en) * | 2000-03-21 | 2001-09-27 | The Procter & Gamble Company | Carbocyclic side chain containing metalloprotease inhibitors |
WO2002006227A1 (fr) * | 2000-07-18 | 2002-01-24 | Chugai Seiyaku Kabushiki Kaisha | Inhibiteurs de la metalloprotease matricielle |
US6452041B1 (en) | 2000-10-16 | 2002-09-17 | Pfizer Inc. | Olefination process to itaconate and succinate derivatives |
GB0025310D0 (en) * | 2000-10-16 | 2000-11-29 | Pfizer Ltd | Process |
US20080279936A1 (en) * | 2001-10-10 | 2008-11-13 | The University Of Pittsburgh | Estradiol metabolites for reduction of endothelin production |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2073513A1 (en) * | 1990-12-03 | 1992-06-04 | John Robert Porter | Peptidyl derivatives |
CA2058797A1 (en) * | 1991-02-01 | 1992-08-02 | Michael John Broadhurst | Amino acid derivatives |
-
1994
- 1994-08-02 WO PCT/GB1994/001697 patent/WO1995004033A1/en active IP Right Grant
- 1994-08-02 AU AU72707/94A patent/AU7270794A/en not_active Abandoned
- 1994-08-02 EP EP94922988A patent/EP0712390B1/de not_active Expired - Lifetime
- 1994-08-02 US US08/586,822 patent/US5827890A/en not_active Expired - Fee Related
- 1994-08-02 DE DE69415159T patent/DE69415159T2/de not_active Expired - Fee Related
- 1994-08-02 JP JP7505702A patent/JPH09503492A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DE69415159D1 (de) | 1999-01-21 |
EP0712390B1 (de) | 1998-12-09 |
JPH09503492A (ja) | 1997-04-08 |
EP0712390A1 (de) | 1996-05-22 |
DE69415159T2 (de) | 1999-07-22 |
WO1995004033A1 (en) | 1995-02-09 |
US5827890A (en) | 1998-10-27 |
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