AU6282494A - 4-aminopyridines, their production and use as an antithrombosis agent - Google Patents

4-aminopyridines, their production and use as an antithrombosis agent

Info

Publication number
AU6282494A
AU6282494A AU62824/94A AU6282494A AU6282494A AU 6282494 A AU6282494 A AU 6282494A AU 62824/94 A AU62824/94 A AU 62824/94A AU 6282494 A AU6282494 A AU 6282494A AU 6282494 A AU6282494 A AU 6282494A
Authority
AU
Australia
Prior art keywords
aminopyridines
production
antithrombosis
agent
antithrombosis agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU62824/94A
Inventor
Herbert Leinert
Thomas +Di Poll
Karlheinz Stegmeier
Wolfgang Von Der Saal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of AU6282494A publication Critical patent/AU6282494A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU62824/94A 1993-03-05 1994-03-02 4-aminopyridines, their production and use as an antithrombosis agent Abandoned AU6282494A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4306873 1993-03-05
DE4306873A DE4306873A1 (en) 1993-03-05 1993-03-05 New 4-aminopyridine processes for their preparation and medicaments containing these compounds
PCT/EP1994/000609 WO1994020468A1 (en) 1993-03-05 1994-03-02 4-aminopyridines, their production and use as an antithrombosis agent

Publications (1)

Publication Number Publication Date
AU6282494A true AU6282494A (en) 1994-09-26

Family

ID=6481990

Family Applications (1)

Application Number Title Priority Date Filing Date
AU62824/94A Abandoned AU6282494A (en) 1993-03-05 1994-03-02 4-aminopyridines, their production and use as an antithrombosis agent

Country Status (8)

Country Link
EP (1) EP0687254A1 (en)
JP (1) JPH08509472A (en)
AU (1) AU6282494A (en)
CA (1) CA2157215A1 (en)
DE (1) DE4306873A1 (en)
IL (1) IL108847A0 (en)
WO (1) WO1994020468A1 (en)
ZA (1) ZA941522B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL115420A0 (en) * 1994-09-26 1995-12-31 Zeneca Ltd Aminoheterocyclic derivatives
US5559150A (en) * 1995-06-06 1996-09-24 3-Dimensional Pharmaceuticals, Inc. N,N-disulfonylated aminobenzene carboxlic acids and the use thereof as thrombin inhibitors
US5741819A (en) * 1995-06-07 1998-04-21 3-Dimensional Pharmaceuticals, Inc. Arylsulfonylaminobenzene derivatives and the use thereof as factor Xa inhibitors
GB9602166D0 (en) * 1996-02-02 1996-04-03 Zeneca Ltd Aminoheterocyclic derivatives
US6313127B1 (en) 1996-02-02 2001-11-06 Zeneca Limited Heterocyclic compounds useful as pharmaceutical agents
ATE230399T1 (en) * 1996-08-14 2003-01-15 Astrazeneca Ab SUBSTITUTED PYRIMIDINE DERIVATIVES AND THEIR PHARMACEUTICAL USE
UA56197C2 (en) 1996-11-08 2003-05-15 Зенека Лімітед Heterocyclic derivatives
JP2001511798A (en) 1997-02-13 2001-08-14 ゼネカ・リミテッド Heterocyclic compounds useful as oxide-squalene cyclase inhibitors
GB9715895D0 (en) 1997-07-29 1997-10-01 Zeneca Ltd Heterocyclic compounds
AU740170B2 (en) * 1997-09-30 2001-11-01 Merck & Co., Inc. Thrombin inhibitors
GB9902989D0 (en) 1999-02-11 1999-03-31 Zeneca Ltd Heterocyclic derivatives
WO2004076434A1 (en) * 2003-02-28 2004-09-10 Aic Dipeptidyl peptidase inhibitors
WO2018050110A1 (en) * 2016-09-18 2018-03-22 正大天晴药业集团股份有限公司 Novel capsid protein assembly inhibitor

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD235866B1 (en) * 1985-03-29 1988-12-28 Univ Leipzig PROCESS FOR PREPARING N ALPHA (2-NAPHTHYL) -SULFONYLAMINOACYLATED AMIDINOPHENYL ALANISAMIDES

Also Published As

Publication number Publication date
ZA941522B (en) 1995-09-04
IL108847A0 (en) 1994-06-24
JPH08509472A (en) 1996-10-08
EP0687254A1 (en) 1995-12-20
CA2157215A1 (en) 1994-09-15
DE4306873A1 (en) 1994-09-08
WO1994020468A1 (en) 1994-09-15

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