AU725928B2 - Improved liquid chromatographic media for polynucleotide separation - Google Patents

Improved liquid chromatographic media for polynucleotide separation Download PDF

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Publication number
AU725928B2
AU725928B2 AU71577/98A AU7157798A AU725928B2 AU 725928 B2 AU725928 B2 AU 725928B2 AU 71577/98 A AU71577/98 A AU 71577/98A AU 7157798 A AU7157798 A AU 7157798A AU 725928 B2 AU725928 B2 AU 725928B2
Authority
AU
Australia
Prior art keywords
beads
silica
separation
mixture
dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU71577/98A
Other languages
English (en)
Other versions
AU7157798A (en
Inventor
Douglas T. Gjerde
Paul D. Taylor
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Precipio Inc
Original Assignee
Transgenomic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transgenomic Inc filed Critical Transgenomic Inc
Publication of AU7157798A publication Critical patent/AU7157798A/en
Application granted granted Critical
Publication of AU725928B2 publication Critical patent/AU725928B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/328—Polymers on the carrier being further modified
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B01J20/287—Non-polar phases; Reversed phases
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3225—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating involving a post-treatment of the coated or impregnated product
    • B01J20/3227—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating involving a post-treatment of the coated or impregnated product by end-capping, i.e. with or after the introduction of functional or ligand groups
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244—Non-macromolecular compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
AU71577/98A 1997-04-25 1998-04-24 Improved liquid chromatographic media for polynucleotide separation Ceased AU725928B2 (en)

Applications Claiming Priority (19)

Application Number Priority Date Filing Date Title
US4485697P 1997-04-25 1997-04-25
US60/044856 1997-04-25
US5545697P 1997-08-11 1997-08-11
US60/055456 1997-08-11
US5952797P 1997-09-22 1997-09-22
US60/059527 1997-09-22
US6212397P 1997-10-15 1997-10-15
US60/062123 1997-10-15
US6230397P 1997-10-17 1997-10-17
US60/062303 1997-10-17
US6361997P 1997-10-27 1997-10-27
US60/063619 1997-10-27
US6931397P 1997-12-05 1997-12-05
US60/069313 1997-12-05
US7799898P 1998-03-13 1998-03-13
US60/077998 1998-03-13
US5833798A 1998-04-10 1998-04-10
US09/058337 1998-04-10
PCT/US1998/008293 WO1998048914A1 (en) 1997-04-25 1998-04-24 Improved liquid chromatographic media for polynucleotide separation

Publications (2)

Publication Number Publication Date
AU7157798A AU7157798A (en) 1998-11-24
AU725928B2 true AU725928B2 (en) 2000-10-26

Family

ID=27578183

Family Applications (1)

Application Number Title Priority Date Filing Date
AU71577/98A Ceased AU725928B2 (en) 1997-04-25 1998-04-24 Improved liquid chromatographic media for polynucleotide separation

Country Status (5)

Country Link
EP (1) EP1027121A4 (de)
JP (1) JP2002506425A (de)
AU (1) AU725928B2 (de)
CA (1) CA2285307A1 (de)
WO (1) WO1998048914A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6475388B1 (en) 1996-11-13 2002-11-05 Transgenomic, Inc. Method and system for RNA analysis by matched ion polynucleotide chromatography
US6576133B2 (en) 1996-11-13 2003-06-10 Transgenomic, Inc Method and system for RNA analysis by matched ion polynucleotide chromatography
US6177559B1 (en) 1998-04-24 2001-01-23 Transgenomic, Inc. Process for separation of polynucleotide fragments
CA2308314A1 (en) * 1997-10-30 1999-05-14 Transgenomic, Inc. Method for high resolution liquid chromatographic separation of polynucleotides
US6258264B1 (en) 1998-04-10 2001-07-10 Transgenomic, Inc. Non-polar media for polynucleotide separations
US6265168B1 (en) 1998-10-06 2001-07-24 Transgenomic, Inc. Apparatus and method for separating and purifying polynucleotides
AU777251B2 (en) * 2000-05-01 2004-10-07 Transgenomic, Inc. Polynucleotide separations on polymeric separation media
CA2396667A1 (en) * 2000-05-26 2001-12-06 Benjamin L. Legendre, Jr. Apparatus and method for separating and purifying polynucleotides
US6521411B2 (en) 2000-09-28 2003-02-18 Transgenomic, Inc. Method and system for the preparation of cDNA
JP4069999B2 (ja) * 2001-03-13 2008-04-02 独立行政法人理化学研究所 ナノ被覆分子性材料
DE10120821A1 (de) * 2001-04-27 2002-10-31 Sachtleben Chemie Gmbh Mit Polyalken beschichtete, poröse Füllstoffe
WO2003031580A2 (en) 2001-10-05 2003-04-17 Transgenomic, Inc. Methods and compositions for mutation analysis by liquid chromatography
WO2012033194A1 (ja) * 2010-09-09 2012-03-15 ダイセル化学工業株式会社 水溶性生体関連物質の分離方法
EP2570183A1 (de) * 2011-09-15 2013-03-20 InstrAction GmbH Sorptionsmittel mit einer aliphatischen Einheit auf dessen Oberfläche zur Reinigung organischer Moleküle
TW201726917A (zh) * 2015-12-28 2017-08-01 昭和電工股份有限公司 分離分析方法
RU2739923C9 (ru) * 2016-05-06 2021-03-01 Голдкорп Инк. Адсорбирующая композиция, способ ее получения и ее применения

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4042327A (en) * 1976-01-15 1977-08-16 Waters Associates, Inc. Ion-pairing chromatography
JPH0637510B2 (ja) * 1985-10-04 1994-05-18 東ソー株式会社 核酸の分離方法
US5015373A (en) * 1988-02-03 1991-05-14 Regents Of The University Of Minnesota High stability porous zirconium oxide spherules
US5100547A (en) * 1991-03-04 1992-03-31 Monsanto Company Chromatography supports consisting of an inorganic susbstrate coated with polybutadiene with alkyl side chains
WO1992015385A1 (en) * 1991-03-04 1992-09-17 Simon Ethan S Butadiene acrylonitrile polymeric coating and chromatographic packing material
AT398973B (de) * 1992-11-18 1995-02-27 Bonn Guenther Dr Verfahren zur trennung von nukleinsäuren
US5772889A (en) * 1995-11-13 1998-06-30 Transgenomic, Inc. System and method for performing nucleic acid separations using liquid chromatography

Also Published As

Publication number Publication date
CA2285307A1 (en) 1998-11-05
EP1027121A1 (de) 2000-08-16
EP1027121A4 (de) 2001-07-11
AU7157798A (en) 1998-11-24
WO1998048914A1 (en) 1998-11-05
JP2002506425A (ja) 2002-02-26

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