AU7214998A - Ngf for the prevention of demyelination in the nervous system - Google Patents

Ngf for the prevention of demyelination in the nervous system Download PDF

Info

Publication number
AU7214998A
AU7214998A AU72149/98A AU7214998A AU7214998A AU 7214998 A AU7214998 A AU 7214998A AU 72149/98 A AU72149/98 A AU 72149/98A AU 7214998 A AU7214998 A AU 7214998A AU 7214998 A AU7214998 A AU 7214998A
Authority
AU
Australia
Prior art keywords
ngf
demyelination
nerve
protease inhibitor
active fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU72149/98A
Other languages
English (en)
Inventor
Ilse Bartke
Claude Genain
Stephen Hauser
Jurgen Unger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of AU7214998A publication Critical patent/AU7214998A/en
Assigned to REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE reassignment REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE Alteration of Name(s) of Applicant(s) under S113 Assignors: ROCHE DIAGNOSTICS GMBH
Priority to AU2002300173A priority Critical patent/AU2002300173B2/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
AU72149/98A 1997-04-11 1998-04-08 Ngf for the prevention of demyelination in the nervous system Abandoned AU7214998A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002300173A AU2002300173B2 (en) 1997-04-11 2002-07-15 NGF for the Prevention of Demyelination in the Nervous System

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83395997A 1997-04-11 1997-04-11
US08833959 1997-04-11
PCT/EP1998/002029 WO1998046254A1 (fr) 1997-04-11 1998-04-08 Facteur de croissance du tissu nerveux pour la prevention de la demyelinisation dans le systeme nerveux

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2002300173A Division AU2002300173B2 (en) 1997-04-11 2002-07-15 NGF for the Prevention of Demyelination in the Nervous System

Publications (1)

Publication Number Publication Date
AU7214998A true AU7214998A (en) 1998-11-11

Family

ID=25265743

Family Applications (1)

Application Number Title Priority Date Filing Date
AU72149/98A Abandoned AU7214998A (en) 1997-04-11 1998-04-08 Ngf for the prevention of demyelination in the nervous system

Country Status (3)

Country Link
AU (1) AU7214998A (fr)
CA (1) CA2286137A1 (fr)
WO (1) WO1998046254A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7282482B2 (en) * 1998-04-08 2007-10-16 The Regents Of The University Of California NGF for the prevention of demyelination in the nervous system
CN1112215C (zh) * 1999-12-28 2003-06-25 潘晓东 神经生长因子在治疗有机溶剂中毒性周围神经病中的用途
SE9904863D0 (sv) * 1999-12-30 1999-12-30 Medscand Medical Ab New use
US8066997B2 (en) 2002-12-20 2011-11-29 Anders Nykjaer Modulation of activity of neurotrophins
DE10317369A1 (de) * 2003-04-15 2004-11-11 Scil Proteins Gmbh proNGF als pharmazeutisch wirksames Mittel zur Behandlung demyelinisierender Erkrankungen
LT3225251T (lt) 2006-12-21 2020-04-10 H. Lundbeck A/S Proneurotrofinų veiklos moduliavimas

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4125933A1 (de) * 1991-08-05 1993-02-11 Max Planck Gesellschaft Verbesserung der regeneration von oligodendrocyten
EP0731108A1 (fr) * 1995-03-10 1996-09-11 Boehringer Mannheim Gmbh Procédé de fabrication d'un agent thérapeutique pour la régénération d'oligodendrocytes
ATE255903T1 (de) * 1995-11-07 2003-12-15 Genentech Inc Stabilisierende formulierung für ngf

Also Published As

Publication number Publication date
WO1998046254A1 (fr) 1998-10-22
CA2286137A1 (fr) 1998-10-22

Similar Documents

Publication Publication Date Title
US7282482B2 (en) NGF for the prevention of demyelination in the nervous system
Sinson et al. Nerve growth factor administration attenuates cognitive but not neurobehavioral motor dysfunction or hippocampal cell loss following fluid‐percussion brain injury in rats
Mansour-Robaey et al. Effects of ocular injury and administration of brain-derived neurotrophic factor on survival and regrowth of axotomized retinal ganglion cells.
Thanos et al. Treatment of the adult retina with microglia-suppressing factors retards axotomy-induced neuronal degradation and enhances axonal regeneration in vivo and in vitro
McLean et al. Recurrent erosion: treatment by anterior stromal puncture
Barker et al. The time course of loss of dopaminergic neurons and the gliotic reaction surrounding grafts of embryonic mesencephalon to the striatum
Nishida et al. Fibronectin enhancement of corneal epithelial wound healing of rabbits in vivo
RU2266129C2 (ru) Способ воздействия на нейродегенеративное нарушение или нарушение миелинизации
RU2242991C2 (ru) Способ лечения церебральных ишемий, а также применение эритропоэтина или производных эритропоэтина для лечения церебральных ишемий
US5958411A (en) Methods of inhibiting ECM accumulation in the CNS by inhibition of TGF-β
US20080176953A1 (en) Methods and compositions for treatment of ocular neovascularization and neural injury
AU7214998A (en) Ngf for the prevention of demyelination in the nervous system
US5510329A (en) Preparations for the treatment of eyes
CN1077799C (zh) 特异性因子对视网膜损伤和变性的预防作用
WO1999003493A1 (fr) Medicaments contenant midkine en tant principe actif ou inhibiteurs desdits medicaments
WO1993008819A1 (fr) Traitement des troubles neurologiques par un compose inhibiteur de l'interleukine-1
AU2002300173B2 (en) NGF for the Prevention of Demyelination in the Nervous System
JP2004500437A (ja) 可動化活性を有する調製物
US20040121958A1 (en) Methods of alleviating neuropathic pain
DE4413938A1 (de) Peptide als Therapeutikum für Autoimmunerkrankungen
EP1057489B1 (fr) Utilisation de proteines de la famille des midkines pour le traitement des maladies ischemiques
Cahn et al. Influence of monosialoganglioside inner ester on neurologic recovery after global cerebral ischemia in monkeys.
Yin et al. Expression of Schwann cell-specific proteins and low-molecular-weight neurofilament protein during regeneration of sciatic nerve treated with neurotrophin-4
Chan et al. Pharmacokinetic study of recombinant human epidermal growth factor in the anterior eye.
EP0878200B1 (fr) Agent therapeutique pour maladies ophtalmiques

Legal Events

Date Code Title Description
PC1 Assignment before grant (sect. 113)

Free format text: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted