AU717611B2 - Tumor-specific antibody fragments, fusion proteins, and uses thereof - Google Patents
Tumor-specific antibody fragments, fusion proteins, and uses thereof Download PDFInfo
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- AU717611B2 AU717611B2 AU41355/96A AU4135596A AU717611B2 AU 717611 B2 AU717611 B2 AU 717611B2 AU 41355/96 A AU41355/96 A AU 41355/96A AU 4135596 A AU4135596 A AU 4135596A AU 717611 B2 AU717611 B2 AU 717611B2
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/34—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood group antigens
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/331397 | 1994-10-28 | ||
| US08/331396 | 1994-10-28 | ||
| US08/331,397 US5981726A (en) | 1990-10-12 | 1994-10-28 | Chimeric and mutationally stabilized tumor-specific B1, B3 and B5 antibody fragments; immunotoxic fusion proteins; and uses thereof |
| US08/331,396 US5889157A (en) | 1990-10-12 | 1994-10-28 | Humanized B3 antibody fragments, fusion proteins, and uses thereof |
| US08/331,398 US5608039A (en) | 1990-10-12 | 1994-10-28 | Single chain B3 antibody fusion proteins and their uses |
| US08/331398 | 1994-10-28 | ||
| PCT/US1995/013811 WO1996013594A1 (fr) | 1994-10-28 | 1995-10-26 | Fragments d'anticorps a specificite tumorale, proteines de fusion, et leurs utilisations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU4135596A AU4135596A (en) | 1996-05-23 |
| AU717611B2 true AU717611B2 (en) | 2000-03-30 |
Family
ID=27406791
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU41355/96A Ceased AU717611B2 (en) | 1994-10-28 | 1995-10-26 | Tumor-specific antibody fragments, fusion proteins, and uses thereof |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0796334A1 (fr) |
| AU (1) | AU717611B2 (fr) |
| CA (1) | CA2203236A1 (fr) |
| WO (1) | WO1996013594A1 (fr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000026394A1 (fr) * | 1998-10-31 | 2000-05-11 | The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Variants de l'anticorps monoclonal anti-carcinome de type humain cc49 |
| US6818749B1 (en) | 1998-10-31 | 2004-11-16 | The United States Of America As Represented By The Department Of Health And Human Services | Variants of humanized anti carcinoma monoclonal antibody cc49 |
| US20050037420A1 (en) * | 2001-09-14 | 2005-02-17 | Mei-Yun Zhang | Immunoglobulin having particular framework scaffold and methods of making and using |
| CA2420494A1 (fr) * | 2003-02-28 | 2004-08-28 | Universite De Sherbrooke | Fonction de l'antigene tumoral ca 125 et utilisations therapeutiques de celui-ci |
| CA2490659C (fr) | 2002-06-28 | 2014-08-19 | Syed V. S. Kashmiri | Les cc49, anti-tag-72 humanises servant au diagnostic et au traitement de tumeurs chez l'homme |
| CU23403A1 (es) | 2003-04-23 | 2009-08-04 | Centro Inmunologia Molecular | Anticuerpos recombinantes y fragmentos que reconocen el gangliósido n-glicolil gm3 y su uso para diagnóstico y tratamiento de tumores |
| US7589181B2 (en) | 2003-08-29 | 2009-09-15 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Minimally immunogenic variants of SDR-grafted humanized antibody CC49 and their use |
| MY146381A (en) * | 2004-12-22 | 2012-08-15 | Amgen Inc | Compositions and methods relating relating to anti-igf-1 receptor antibodies |
| JO2913B1 (en) | 2008-02-20 | 2015-09-15 | امجين إنك, | Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses |
| GB201910899D0 (en) * | 2019-07-31 | 2019-09-11 | Scancell Ltd | Binding members |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3512795B2 (ja) * | 1991-09-30 | 2004-03-31 | アメリカ合衆国 | 組換免疫毒素 |
-
1995
- 1995-10-26 EP EP95939599A patent/EP0796334A1/fr not_active Withdrawn
- 1995-10-26 CA CA 2203236 patent/CA2203236A1/fr not_active Abandoned
- 1995-10-26 AU AU41355/96A patent/AU717611B2/en not_active Ceased
- 1995-10-26 WO PCT/US1995/013811 patent/WO1996013594A1/fr not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU4135596A (en) | 1996-05-23 |
| WO1996013594A8 (fr) | 2000-04-06 |
| WO1996013594A1 (fr) | 1996-05-09 |
| CA2203236A1 (fr) | 1996-05-09 |
| EP0796334A1 (fr) | 1997-09-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TH | Corrigenda |
Free format text: IN VOL 13, NO 44, PAGE(S) 6728 UNDER THE HEADING APPLICATIONS LAPSED, REFUSED OR WITHDRAWN PLEASE DELETE ALL REFERENCE TO PATENT APPLICATION NO. 41355/96 |
|
| FGA | Letters patent sealed or granted (standard patent) |