AU703101B2 - Treatment or prevention of neoplastic and infectious diseases with heat shock/stress proteins - Google Patents
Treatment or prevention of neoplastic and infectious diseases with heat shock/stress proteinsInfo
- Publication number
- AU703101B2 AU703101B2 AU70181/96A AU7018196A AU703101B2 AU 703101 B2 AU703101 B2 AU 703101B2 AU 70181/96 A AU70181/96 A AU 70181/96A AU 7018196 A AU7018196 A AU 7018196A AU 703101 B2 AU703101 B2 AU 703101B2
- Authority
- AU
- Australia
- Prior art keywords
- complex
- micrograms
- cancer
- individual
- amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001176—Heat shock proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56977—HLA or MHC typing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5152—Tumor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6043—Heat shock proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
- A61K2039/622—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier non-covalent binding
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Hospice & Palliative Care (AREA)
- Tropical Medicine & Parasitology (AREA)
- Zoology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US527391 | 1995-09-13 | ||
| US08/527,391 US5837251A (en) | 1995-09-13 | 1995-09-13 | Compositions and methods using complexes of heat shock proteins and antigenic molecules for the treatment and prevention of neoplastic diseases |
| PCT/US1996/014557 WO1997010001A1 (en) | 1995-09-13 | 1996-09-11 | Treatment or prevention of neoplastic and infectious diseases with heat shock/stress proteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU7018196A AU7018196A (en) | 1997-04-01 |
| AU703101B2 true AU703101B2 (en) | 1999-03-18 |
Family
ID=24101273
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU70181/96A Ceased AU703101B2 (en) | 1995-09-13 | 1996-09-11 | Treatment or prevention of neoplastic and infectious diseases with heat shock/stress proteins |
Country Status (10)
| Country | Link |
|---|---|
| US (8) | US5837251A (enExample) |
| EP (1) | EP0859631B9 (enExample) |
| JP (1) | JPH11514985A (enExample) |
| AT (1) | ATE456378T1 (enExample) |
| AU (1) | AU703101B2 (enExample) |
| CA (1) | CA2232048C (enExample) |
| DE (1) | DE69638121D1 (enExample) |
| ES (1) | ES2340558T3 (enExample) |
| WO (1) | WO1997010001A1 (enExample) |
| ZA (1) | ZA967757B (enExample) |
Families Citing this family (114)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5750119A (en) * | 1994-01-13 | 1998-05-12 | Mount Sinai School Of Medicine Of The City University Of New York | Immunotherapeutic stress protein-peptide complexes against cancer |
| US5997873A (en) * | 1994-01-13 | 1999-12-07 | Mount Sinai School Of Medicine Of The City University Of New York | Method of preparation of heat shock protein 70-peptide complexes |
| US5961979A (en) * | 1994-03-16 | 1999-10-05 | Mount Sinai School Of Medicine Of The City University Of New York | Stress protein-peptide complexes as prophylactic and therapeutic vaccines against intracellular pathogens |
| US6761892B1 (en) * | 1995-08-18 | 2004-07-13 | Sloan-Kettering Institute For Cancer Research | Heat shock protein-based vaccines and immunotherapies |
| US6331299B1 (en) | 1995-08-18 | 2001-12-18 | Sloan-Kettering Institute For Cancer Research | Method for treatment of cancer and infectious disease and compositions useful in same |
| US6719974B1 (en) | 1995-08-18 | 2004-04-13 | Sloan-Kettering Institute For Cancer Research | Heat shock protein-based vaccines and immunotherapies |
| US6773707B1 (en) * | 1995-08-18 | 2004-08-10 | Sloan-Kettering Institute For Cancer Research | Heat shock protein-based vaccines and immunotherapies |
| CA2229543A1 (en) | 1995-08-18 | 1997-02-27 | Sloan-Kettering Institute For Cancer Research | Heat shock protein-based vaccines and immunotherapies |
| US5985270A (en) * | 1995-09-13 | 1999-11-16 | Fordham University | Adoptive immunotherapy using macrophages sensitized with heat shock protein-epitope complexes |
| US5935576A (en) | 1995-09-13 | 1999-08-10 | Fordham University | Compositions and methods for the treatment and prevention of neoplastic diseases using heat shock proteins complexed with exogenous antigens |
| US5837251A (en) * | 1995-09-13 | 1998-11-17 | Fordham University | Compositions and methods using complexes of heat shock proteins and antigenic molecules for the treatment and prevention of neoplastic diseases |
| CA2265935C (en) * | 1996-09-20 | 2006-09-05 | The University Of New Mexico | Heat shock protein complexes |
| US6455493B1 (en) | 1996-09-20 | 2002-09-24 | University Of New Mexico | Methods for using heat shock proteins |
| US7157089B1 (en) * | 1996-11-26 | 2007-01-02 | Stressgen Biotechnologies Corporation | Immune responses using compositions containing stress proteins |
| US7514232B2 (en) * | 1996-12-06 | 2009-04-07 | Becton, Dickinson And Company | Method for detecting T cell response to specific antigens in whole blood |
| US6017540A (en) | 1997-02-07 | 2000-01-25 | Fordham University | Prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases with heat shock/stress protein-peptide complexes |
| US6709672B2 (en) * | 1997-03-05 | 2004-03-23 | Biotech Tools S.A. | Pharmaceutical or food composition for treating pathologies associated with graft rejection or an allergic or autoimmune reaction |
| JP2001509396A (ja) * | 1997-07-10 | 2001-07-24 | メディカル リサーチ カウンシル | シャペロン断片 |
| HUP0003601A3 (en) * | 1997-08-05 | 2003-03-28 | Stressgen Biotechnologies Corp | Immune responses against hpv antigens elicited by compositions comprising an hpv antigen and a stress protein or an expression vector capable of expression of these proteins |
| US6007821A (en) * | 1997-10-16 | 1999-12-28 | Fordham University | Method and compositions for the treatment of autoimmune disease using heat shock proteins |
| JP2002501722A (ja) * | 1997-10-31 | 2002-01-22 | スローン−ケターリング インスティチュート フォー キャンサー リサーチ | 熱ショックタンパク質結合性コンジュゲートペプチド |
| US5948646A (en) | 1997-12-11 | 1999-09-07 | Fordham University | Methods for preparation of vaccines against cancer comprising heat shock protein-peptide complexes |
| EP1054683B1 (en) * | 1998-02-20 | 2007-04-11 | University Of Miami | Modified heat shock protein-antigenic peptide complex |
| WO1999048914A1 (en) * | 1998-03-26 | 1999-09-30 | The University Of New Mexico | Methods for using heat shock proteins |
| WO1999049881A2 (de) * | 1998-03-27 | 1999-10-07 | Gabriele Multhoff | Verwendung von hsp70 protein |
| GB9818133D0 (en) * | 1998-08-19 | 1998-10-14 | Quadrant Holdings Cambridge | Vaccine |
| AU2004200711B2 (en) * | 1998-08-19 | 2005-11-10 | Immunobiology Limited | Vaccine Comprising Cytokine-Induced Heat Shock Proteins (HSP) |
| US6475490B1 (en) | 1998-10-19 | 2002-11-05 | Fordham University | Compositions and methods for promoting tissue repair using heat shock proteins |
| US6495360B1 (en) | 1999-05-28 | 2002-12-17 | Photogen, Inc. | Method for enhanced protein stabilization and for production of cell lines useful for production of such stabilized proteins |
| EP1196772A2 (en) * | 1999-07-08 | 2002-04-17 | Stressgen Biotechnologies Corporation | Induction of a th1-like response in vitro |
| GB9919733D0 (en) * | 1999-08-19 | 1999-10-20 | Colaco Camilo | Vaccines against intracellular pathogens |
| AUPQ233799A0 (en) | 1999-08-19 | 1999-09-09 | Minister For Agriculture, Minister For Land And Water Conservation For And On Behalf Of The State Of New South Wales | Recombinant sub-unit vaccine |
| US7378096B2 (en) | 1999-09-30 | 2008-05-27 | Health Research, Inc. | Stress protein compositions and methods for prevention and treatment of cancer and infectious disease |
| WO2001023421A2 (en) * | 1999-09-30 | 2001-04-05 | Corixa Corporation | Stress protein compositions and methods for prevention and treatment of cancer and infectious disease |
| US8128922B2 (en) * | 1999-10-20 | 2012-03-06 | Johns Hopkins University | Superior molecular vaccine linking the translocation domain of a bacterial toxin to an antigen |
| US7030228B1 (en) | 1999-11-15 | 2006-04-18 | Miltenyi Biotec Gmbh | Antigen-binding fragments specific for dendritic cells, compositions and methods of use thereof antigens recognized thereby and cells obtained thereby |
| US20010034042A1 (en) * | 2000-01-20 | 2001-10-25 | Srivastava Pramod K. | Complexes of peptide-binding fragments of heat shock proteins and their use as immunotherapeutic agents |
| US7235649B2 (en) * | 2000-03-24 | 2007-06-26 | Duke University | Isolated GRP94 ligand binding domain polypeptide and nucleic acid encoding same, and screening methods employing same |
| WO2001091787A1 (en) | 2000-06-02 | 2001-12-06 | University Of Connecticut Health Center | Complexes of alpha (2) macroglobulin and antigenic molecules for immunotherapy |
| US7179462B2 (en) | 2000-06-02 | 2007-02-20 | University Of Connecticut Health Center | α (2) macroglobulin receptor as a heat shock protein receptor and uses thereof |
| US7186515B1 (en) | 2000-06-02 | 2007-03-06 | University Of Connecticut Health Center | Alpha(2) macroglobulin receptor as a heat shock protein receptor and uses thereof |
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| EP1322747A4 (en) * | 2000-09-15 | 2004-12-29 | Univ Connecticut Health Ct | IMPROVED FORMULATIONS USING THERMAL SHOCK / STRESS PEPTIDE-PROTEIN COMPLEXES |
| EP1326637A2 (en) * | 2000-10-18 | 2003-07-16 | Tengiz A. Jaliashvili | Vaccine comprising heat stress proteins from herbaceous plants |
| US20020172682A1 (en) * | 2000-10-20 | 2002-11-21 | University Of Connecticut Health Center | Using heat shock proteins to increase immune response |
| US7132109B1 (en) | 2000-10-20 | 2006-11-07 | University Of Connecticut Health Center | Using heat shock proteins to increase immune response |
| US6892140B1 (en) | 2000-11-27 | 2005-05-10 | Enteron, Inc. | Immunogenic cancer peptides and uses thereof |
| KR20030074787A (ko) * | 2001-02-05 | 2003-09-19 | 스트레스젠 바이오테크놀러지스 코포레이션 | B형 간염 바이러스 치료 |
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| US6875849B2 (en) * | 2001-05-01 | 2005-04-05 | Arizona Board Of Regents Of Behalf Of The University Of Arizona | Methods of recovering chaperone proteins and complexes thereof |
| RU2182480C1 (ru) * | 2001-05-16 | 2002-05-20 | Хохлов Александр Петрович | Противоопухолевый препарат и способ его получения |
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| WO2003015712A2 (en) * | 2001-08-20 | 2003-02-27 | University Of Connecticut Health Center | Methods for preparing compositions comprising heat shock proteins or alpha-2-macroglobulin |
| US20030211971A1 (en) * | 2001-09-17 | 2003-11-13 | Srivastava Pramod K. | Compositions and methods for prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases with compositions comprising unfractionated cellular proteins |
| CA2460396A1 (en) * | 2001-10-01 | 2003-04-10 | Duke University | Isolated grp94 ligand binding domain polypeptide and nucleic acid encoding same, crystalline form of same, and screening methods employing same |
| US20030194409A1 (en) * | 2002-01-17 | 2003-10-16 | Rothman James E. | Conjugate heat shock protein-binding peptides |
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| RU2376029C2 (ru) * | 2002-04-25 | 2009-12-20 | Юниверсити Оф Коннектикут Хелт Сентер | Применение белков теплового шока для улучшения терапевтического эффекта невакцинного лечебного воздействия |
| AU2003234469A1 (en) * | 2002-05-02 | 2003-11-17 | University Of Connecticut Health Center | Use of heat shock proteins to enhance efficacy of antibody therapeutics |
| US20030206916A1 (en) * | 2002-05-03 | 2003-11-06 | Rush-Presbyterian-St. Luke's Medical Center | Immunogenic peptides |
| US20050004001A1 (en) * | 2002-10-02 | 2005-01-06 | Robert Harris | Formulation of antigen |
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-
1995
- 1995-09-13 US US08/527,391 patent/US5837251A/en not_active Expired - Lifetime
-
1996
- 1996-09-11 AT AT96931527T patent/ATE456378T1/de not_active IP Right Cessation
- 1996-09-11 ES ES96931527T patent/ES2340558T3/es not_active Expired - Lifetime
- 1996-09-11 DE DE69638121T patent/DE69638121D1/de not_active Expired - Lifetime
- 1996-09-11 WO PCT/US1996/014557 patent/WO1997010001A1/en not_active Ceased
- 1996-09-11 AU AU70181/96A patent/AU703101B2/en not_active Ceased
- 1996-09-11 JP JP9512063A patent/JPH11514985A/ja active Pending
- 1996-09-11 CA CA2232048A patent/CA2232048C/en not_active Expired - Fee Related
- 1996-09-11 EP EP96931527A patent/EP0859631B9/en not_active Expired - Lifetime
- 1996-09-13 ZA ZA967757A patent/ZA967757B/xx unknown
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1998
- 1998-06-04 US US09/090,754 patent/US7601359B1/en not_active Expired - Fee Related
- 1998-09-09 US US09/150,041 patent/US6162436A/en not_active Expired - Fee Related
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- 1998-09-09 US US09/150,203 patent/US6143299A/en not_active Expired - Lifetime
- 1998-09-09 US US09/150,040 patent/US6187312B1/en not_active Expired - Lifetime
- 1998-09-09 US US09/150,204 patent/US6136315A/en not_active Expired - Lifetime
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2003
- 2003-08-12 US US10/640,604 patent/US20040047876A1/en not_active Abandoned
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| EP0859631A1 (en) | 1998-08-26 |
| WO1997010001A1 (en) | 1997-03-20 |
| CA2232048A1 (en) | 1997-03-20 |
| US20040047876A1 (en) | 2004-03-11 |
| ATE456378T1 (de) | 2010-02-15 |
| US6136315A (en) | 2000-10-24 |
| EP0859631B1 (en) | 2010-01-27 |
| US6162436A (en) | 2000-12-19 |
| EP0859631B9 (en) | 2010-07-28 |
| US7601359B1 (en) | 2009-10-13 |
| ES2340558T3 (es) | 2010-06-04 |
| US6139841A (en) | 2000-10-31 |
| CA2232048C (en) | 2014-04-29 |
| JPH11514985A (ja) | 1999-12-21 |
| DE69638121D1 (de) | 2010-03-18 |
| AU7018196A (en) | 1997-04-01 |
| US5837251A (en) | 1998-11-17 |
| ZA967757B (en) | 1997-04-07 |
| EP0859631A4 (en) | 2002-07-31 |
| US6187312B1 (en) | 2001-02-13 |
| US6143299A (en) | 2000-11-07 |
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