AU696622B2 - Inhibitors of phosphoinositide-specific phospholipase C - Google Patents
Inhibitors of phosphoinositide-specific phospholipase CInfo
- Publication number
- AU696622B2 AU696622B2 AU79738/94A AU7973894A AU696622B2 AU 696622 B2 AU696622 B2 AU 696622B2 AU 79738/94 A AU79738/94 A AU 79738/94A AU 7973894 A AU7973894 A AU 7973894A AU 696622 B2 AU696622 B2 AU 696622B2
- Authority
- AU
- Australia
- Prior art keywords
- hydrogen
- glu
- leu
- mammal
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
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- 108010079194 Type C Phospholipases Proteins 0.000 title claims description 29
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- 239000001257 hydrogen Substances 0.000 claims description 31
- 238000000034 method Methods 0.000 claims description 29
- 125000001424 substituent group Chemical group 0.000 claims description 20
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- 241000124008 Mammalia Species 0.000 claims description 18
- 150000003839 salts Chemical class 0.000 claims description 16
- 230000002401 inhibitory effect Effects 0.000 claims description 14
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- 230000004054 inflammatory process Effects 0.000 claims description 8
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 8
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- C—CHEMISTRY; METALLURGY
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- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/138,133 US5519163A (en) | 1993-10-15 | 1993-10-15 | Inhibitors of phosphoinositide-specific phospholipase C |
PCT/US1994/011497 WO1995010286A1 (en) | 1993-10-15 | 1994-10-11 | Inhibitors of phosphoinositide-specific phospholipase c |
US138133 | 1998-08-21 |
Publications (2)
Publication Number | Publication Date |
---|---|
AU7973894A AU7973894A (en) | 1995-05-04 |
AU696622B2 true AU696622B2 (en) | 1998-09-17 |
Family
ID=22480566
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU79738/94A Ceased AU696622B2 (en) | 1993-10-15 | 1994-10-11 | Inhibitors of phosphoinositide-specific phospholipase C |
Country Status (6)
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1379235T3 (da) | 2000-10-10 | 2007-01-29 | Univ North Carolina | Sammensætninger og fremgangsmåder til forbedring af paracellulær permeabilitet over epithel- og endothelbarrierer |
US20020107193A1 (en) * | 2000-11-09 | 2002-08-08 | Glazner Gordon W. | Therapeutic uses for IP3 receptor-mediated calcium channel modulators |
EP1504013A4 (en) * | 2002-05-11 | 2006-05-03 | Ilex Products Inc | USE OF HYDROXYPHOSPHONATES AND PHOSPHONOPHOSPHATES AS MODULATORS OF APOLIPOPROTEIN E |
EP1689383B1 (en) * | 2003-11-19 | 2012-10-31 | Metabasis Therapeutics, Inc. | Novel phosphorus-containing thyromimetics |
EP1566447A1 (en) * | 2004-02-20 | 2005-08-24 | Aventis Pharma Deutschland GmbH | Glimepiride- and insulin-induced glycosylphosphatidylinositol-specific phospholipase C regulation |
MX2007014502A (es) | 2005-05-26 | 2008-02-07 | Metabasis Therapeutics Inc | Tiromimeticos para el tratamiento de enfermedades del higado graso. |
WO2006133128A2 (en) * | 2005-06-07 | 2006-12-14 | The Regents Of The University Of California | INHIBITION OF EPAC, PHOSPHOLIPASE Cϵ, AND PHOSPHOLIPASE D TO TREAT PAIN |
US9547017B2 (en) * | 2012-03-15 | 2017-01-17 | Montana Molecular Llc | Genetically encoded fluorescent sensors for detecting intracellular signalling through diacylglycerol pathways |
EP3065754B1 (en) | 2013-11-04 | 2020-06-10 | Montana Molecular LLC | GENETICALLY ENCODED FLUORESCENT SENSORS FOR DETECTING LIGAND BIAS AND INTRACELLULAR SIGNALING THROUGH cAMP PATHWAYS |
US11202789B2 (en) | 2016-11-21 | 2021-12-21 | Viking Therapeutics, Inc. | Method of treating glycogen storage disease |
JP7168660B2 (ja) | 2017-06-05 | 2022-11-09 | バイキング・セラピューティクス・インコーポレイテッド | 線維症の処置のための組成物 |
WO2019183004A1 (en) | 2018-03-22 | 2019-09-26 | Viking Therapeutics, Inc. | Crystalline forms and methods of producing crystalline forms of a compound |
CN109516623B (zh) * | 2018-11-16 | 2021-06-01 | 浙江万盛股份有限公司 | 一种三丁氧乙基磷酸酯废水的综合利用方法 |
EP3890747A4 (en) | 2018-12-05 | 2022-08-03 | Viking Therapeutics, Inc. | COMPOSITIONS FOR THE TREATMENT OF FIBROSIS AND INFLAMMATION |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4474806A (en) * | 1982-05-10 | 1984-10-02 | Merck & Co., Inc. | Sulfonyl or carbonyl inositol derivatives useful as anti-inflammatory/analgesic agents |
-
1993
- 1993-10-15 US US08/138,133 patent/US5519163A/en not_active Expired - Fee Related
-
1994
- 1994-10-11 WO PCT/US1994/011497 patent/WO1995010286A1/en not_active Application Discontinuation
- 1994-10-11 EP EP94930696A patent/EP0746323A1/en not_active Withdrawn
- 1994-10-11 AU AU79738/94A patent/AU696622B2/en not_active Ceased
- 1994-10-11 CA CA002173456A patent/CA2173456A1/en not_active Abandoned
- 1994-10-11 JP JP7511980A patent/JPH09505033A/ja active Pending
Non-Patent Citations (1)
Title |
---|
CHEM. ABS, 118, 1993, 39033T * |
Also Published As
Publication number | Publication date |
---|---|
WO1995010286A1 (en) | 1995-04-20 |
US5519163A (en) | 1996-05-21 |
EP0746323A4 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1997-01-22 |
CA2173456A1 (en) | 1995-04-20 |
AU7973894A (en) | 1995-05-04 |
JPH09505033A (ja) | 1997-05-20 |
EP0746323A1 (en) | 1996-12-11 |
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