AU6932300A - Dilutions in high throughput systems with a single vacuum source - Google Patents

Dilutions in high throughput systems with a single vacuum source Download PDF

Info

Publication number
AU6932300A
AU6932300A AU69323/00A AU6932300A AU6932300A AU 6932300 A AU6932300 A AU 6932300A AU 69323/00 A AU69323/00 A AU 69323/00A AU 6932300 A AU6932300 A AU 6932300A AU 6932300 A AU6932300 A AU 6932300A
Authority
AU
Australia
Prior art keywords
main channel
channel
fluidic material
channels
flow reduction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU69323/00A
Other languages
English (en)
Inventor
Andrea W. Chow
Anne R. Kopf-Sill
Claudia L. Poglitsch
Steven A Sundberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Caliper Life Sciences Inc
Original Assignee
Caliper Technologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Caliper Technologies Corp filed Critical Caliper Technologies Corp
Publication of AU6932300A publication Critical patent/AU6932300A/en
Abandoned legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles or throttle valves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44791—Microapparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0883—Serpentine channels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B01L2400/049—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38—Diluting, dispersing or mixing samples

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
AU69323/00A 1999-08-25 2000-08-23 Dilutions in high throughput systems with a single vacuum source Abandoned AU6932300A (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US15067099P 1999-08-25 1999-08-25
US60150670 1999-08-25
US15901499P 1999-10-12 1999-10-12
US60159014 1999-10-12
US20013900P 2000-04-27 2000-04-27
US60200139 2000-04-27
PCT/US2000/023220 WO2001014865A1 (en) 1999-08-25 2000-08-23 Dilutions in high throughput systems with a single vacuum source

Publications (1)

Publication Number Publication Date
AU6932300A true AU6932300A (en) 2001-03-19

Family

ID=27387014

Family Applications (1)

Application Number Title Priority Date Filing Date
AU69323/00A Abandoned AU6932300A (en) 1999-08-25 2000-08-23 Dilutions in high throughput systems with a single vacuum source

Country Status (5)

Country Link
EP (1) EP1208370A4 (https=)
JP (1) JP4119649B2 (https=)
AU (1) AU6932300A (https=)
CA (1) CA2380897A1 (https=)
WO (1) WO2001014865A1 (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7037416B2 (en) 2000-01-14 2006-05-02 Caliper Life Sciences, Inc. Method for monitoring flow rate using fluorescent markers
US20090118139A1 (en) 2000-11-07 2009-05-07 Caliper Life Sciences, Inc. Microfluidic method and system for enzyme inhibition activity screening
US7723099B2 (en) * 2003-09-10 2010-05-25 Abbott Point Of Care Inc. Immunoassay device with immuno-reference electrode
US7740806B2 (en) * 2006-02-28 2010-06-22 International Business Machines Corporation Ceramic microarray spotting device for bioassay printing
US8202486B2 (en) * 2009-08-12 2012-06-19 Caliper Life Sciences, Inc. Pinching channels for fractionation of fragmented samples
ES2649559T3 (es) * 2009-11-23 2018-01-12 Cyvek, Inc. Método y aparato para realizar ensayos
WO2013134741A2 (en) 2012-03-08 2013-09-12 Cyvek, Inc. Methods and systems for manufacture of microarray assay systems, conducting microfluidic assays, and monitoring and scanning to obtain microfluidic assay results
US9500645B2 (en) 2009-11-23 2016-11-22 Cyvek, Inc. Micro-tube particles for microfluidic assays and methods of manufacture
US9855735B2 (en) 2009-11-23 2018-01-02 Cyvek, Inc. Portable microfluidic assay devices and methods of manufacture and use
US9651568B2 (en) 2009-11-23 2017-05-16 Cyvek, Inc. Methods and systems for epi-fluorescent monitoring and scanning for microfluidic assays
US9700889B2 (en) 2009-11-23 2017-07-11 Cyvek, Inc. Methods and systems for manufacture of microarray assay systems, conducting microfluidic assays, and monitoring and scanning to obtain microfluidic assay results
US10065403B2 (en) 2009-11-23 2018-09-04 Cyvek, Inc. Microfluidic assay assemblies and methods of manufacture
US9759718B2 (en) 2009-11-23 2017-09-12 Cyvek, Inc. PDMS membrane-confined nucleic acid and antibody/antigen-functionalized microlength tube capture elements, and systems employing them, and methods of their use
US9421540B2 (en) 2010-10-28 2016-08-23 International Business Machines Corporation Microfluidic device with auxiliary and bypass channels
WO2012129455A2 (en) 2011-03-22 2012-09-27 Cyvek, Inc Microfluidic devices and methods of manufacture and use
JP6449266B2 (ja) 2013-06-21 2019-01-09 バイオ−ラッド・ラボラトリーズ・インコーポレーテッド 流体ピックアップを備えるマイクロ流体システム
KR102587637B1 (ko) 2014-12-12 2023-10-10 옵코 다이어그노스틱스, 엘엘씨 성형에 의해 제조되는 유체 시스템을 비롯한, 항온 처리 채널을 포함하는 유체 시스템
US10048190B2 (en) 2015-01-21 2018-08-14 Sbt Instruments Aps Microfluidic particle analysis device
US10228367B2 (en) 2015-12-01 2019-03-12 ProteinSimple Segmented multi-use automated assay cartridge
WO2018148693A1 (en) 2017-02-13 2018-08-16 Bio-Rad Laboratories, Inc. System, method, and device for forming an array of emulsions
EP3791956B1 (en) * 2019-09-11 2023-04-12 CSEM Centre Suisse D'electronique Et De Microtechnique SA Microfluidic sensing device and cartridge, and corresponding methods

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5779868A (en) * 1996-06-28 1998-07-14 Caliper Technologies Corporation Electropipettor and compensation means for electrophoretic bias
US5869004A (en) * 1997-06-09 1999-02-09 Caliper Technologies Corp. Methods and apparatus for in situ concentration and/or dilution of materials in microfluidic systems

Also Published As

Publication number Publication date
JP4119649B2 (ja) 2008-07-16
EP1208370A1 (en) 2002-05-29
EP1208370A4 (en) 2006-05-31
JP2003507737A (ja) 2003-02-25
CA2380897A1 (en) 2001-03-01
WO2001014865A1 (en) 2001-03-01

Similar Documents

Publication Publication Date Title
US6858185B1 (en) Dilutions in high throughput systems with a single vacuum source
US7037416B2 (en) Method for monitoring flow rate using fluorescent markers
AU6932300A (en) Dilutions in high throughput systems with a single vacuum source
US6613580B1 (en) Microfluidic systems and methods for determining modulator kinetics
US9683994B2 (en) High throughput mobility shift
US8216852B2 (en) Channel cross-section geometry to manipulate dispersion rates
US7758737B1 (en) Total analyte quantitation
US20050006238A1 (en) Pressure induced reagent introduction and electrophoretic separation
EP1409989B1 (en) Method for separating components of a mixture
US7846392B2 (en) Prevention of precipitate blockage in microfluidic channels
US6613581B1 (en) Microfluidic analytic detection assays, devices, and integrated systems
US6703205B2 (en) Apparatus and methods for correcting for variable velocity in microfluidic systems
US20020001856A1 (en) Methods and devices for achieving long incubation times in high-throughput systems
US6857449B1 (en) Multi-layer microfluidic devices
US20020187564A1 (en) Microfluidic library analysis
WO1999064840A1 (en) Fluorescent polarization detection in microfluidic systems
US20020110926A1 (en) Emulator device