AU6871196A - Use of prostane derivatives and the combination thereof with antibiotics in the treatment of bacterial infections - Google Patents

Use of prostane derivatives and the combination thereof with antibiotics in the treatment of bacterial infections

Info

Publication number
AU6871196A
AU6871196A AU68711/96A AU6871196A AU6871196A AU 6871196 A AU6871196 A AU 6871196A AU 68711/96 A AU68711/96 A AU 68711/96A AU 6871196 A AU6871196 A AU 6871196A AU 6871196 A AU6871196 A AU 6871196A
Authority
AU
Australia
Prior art keywords
pct
combination
antibiotics
treatment
bacterial infections
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU68711/96A
Other versions
AU702706B2 (en
Inventor
Klemens Angstwurm
Peter Scholz
Jorg Weber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of AU6871196A publication Critical patent/AU6871196A/en
Application granted granted Critical
Publication of AU702706B2 publication Critical patent/AU702706B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/558—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
    • A61K31/5585—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes having five-membered rings containing oxygen as the only ring hetero atom, e.g. prostacyclin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PCT No. PCT/EP96/03481 Sec. 371 Date Apr. 23, 1998 Sec. 102(e) Date Apr. 23, 1998 PCT Filed Aug. 6, 1996 PCT Pub. No. WO97/06806 PCT Pub. Date Feb. 27, 1997A method is described for treating bacterially induced meningitis, comprising administering a prostane derivative of formula I or Ia wherein X1, X2, X3, X4, X5, R1, R2, R3 and R4 are as described below, and the -O-R3- group is in the alpha - or beta -configuration. The prostane derivative can optionally comprise or serve as an adjuvant, and it can be administered in combination with an antiobiotic.
AU68711/96A 1995-08-11 1996-08-06 Use of prostane derivatives and the combination thereof with antibiotics in the treatment of bacterial infections Ceased AU702706B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19530884A DE19530884C2 (en) 1995-08-11 1995-08-11 Use of prostane derivatives and their combination with antibiotics for the treatment of bacterial meningitis
DE19530884 1995-08-11
PCT/EP1996/003481 WO1997006806A1 (en) 1995-08-11 1996-08-06 Use of prostane derivatives and the combination thereof with antibiotics in the treatment of bacterial infections

Publications (2)

Publication Number Publication Date
AU6871196A true AU6871196A (en) 1997-03-12
AU702706B2 AU702706B2 (en) 1999-03-04

Family

ID=7770106

Family Applications (1)

Application Number Title Priority Date Filing Date
AU68711/96A Ceased AU702706B2 (en) 1995-08-11 1996-08-06 Use of prostane derivatives and the combination thereof with antibiotics in the treatment of bacterial infections

Country Status (25)

Country Link
US (1) US6040336A (en)
EP (1) EP0852497B1 (en)
JP (1) JPH11510809A (en)
CN (1) CN1080562C (en)
AT (1) ATE219368T1 (en)
AU (1) AU702706B2 (en)
BR (1) BR9609932A (en)
CA (1) CA2228036A1 (en)
CZ (1) CZ291534B6 (en)
DE (2) DE19530884C2 (en)
DK (1) DK0852497T3 (en)
ES (1) ES2181907T3 (en)
HK (1) HK1015707A1 (en)
HU (1) HUP9802450A3 (en)
IL (1) IL122826A (en)
MX (1) MX9801118A (en)
NO (1) NO316424B1 (en)
PL (1) PL184840B1 (en)
PT (1) PT852497E (en)
RU (1) RU2201232C2 (en)
SK (1) SK284195B6 (en)
TR (1) TR199800128T1 (en)
UA (1) UA54397C2 (en)
WO (1) WO1997006806A1 (en)
ZA (1) ZA966775B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6663967B1 (en) * 2000-11-17 2003-12-16 Bryant Rubber Corporation Moldable silicone elastomers having selective primerless adhesion
US8183286B2 (en) * 2006-11-16 2012-05-22 Gemmus Pharma Inc. EP2 and EP4 agonists as agents for the treatment of influenza a viral infection
EP2803365A1 (en) 2013-05-14 2014-11-19 Commissariat A L'energie Atomique Et Aux Energies Alternatives Use of clonazepam in combination with antibiotic in the treatment of bacterially induced meningitis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US447802A (en) * 1891-03-10 Irvest williams
DE2845770A1 (en) * 1978-10-19 1980-04-30 Schering Ag NEW PROSTACYCLINE DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF
JPS58124778A (en) * 1982-01-20 1983-07-25 Toray Ind Inc 5,6,7-trinor-4,8-inter-m-phenylene pgi2 derivative
US4665088A (en) * 1984-11-14 1987-05-12 The Research Foundation Of State University Of New York (E-Z)-4,5,9-trithiadodeca-1,6,11-triene 9-oxides
ZA871143B (en) * 1986-02-18 1988-09-28 Syntex Inc Anti-infective injectable formulations
DE4104607A1 (en) * 1991-02-12 1992-08-13 Schering Ag PROSTACYCLIN AND CARBACYCLINE DERIVATIVES AS A MEDIUM FOR TREATING FEVERED DISEASES
EP0758233B1 (en) * 1994-04-21 2003-12-03 Schering Aktiengesellschaft Pde iv inhibitors for treating multiple sclerosis

Also Published As

Publication number Publication date
CZ291534B6 (en) 2003-03-12
ZA966775B (en) 1997-02-19
DK0852497T3 (en) 2002-08-12
US6040336A (en) 2000-03-21
PT852497E (en) 2002-10-31
EP0852497B1 (en) 2002-06-19
WO1997006806A1 (en) 1997-02-27
IL122826A0 (en) 1998-08-16
PL324884A1 (en) 1998-06-22
NO980568L (en) 1998-02-10
HUP9802450A3 (en) 1999-08-30
UA54397C2 (en) 2003-03-17
HK1015707A1 (en) 1999-10-22
PL184840B1 (en) 2002-12-31
TR199800128T1 (en) 1998-04-21
MX9801118A (en) 1998-10-31
CN1192684A (en) 1998-09-09
SK284195B6 (en) 2004-10-05
NO980568D0 (en) 1998-02-10
CZ41498A3 (en) 1998-09-16
EP0852497A1 (en) 1998-07-15
DE69621939D1 (en) 2002-07-25
DE69621939T2 (en) 2003-01-09
JPH11510809A (en) 1999-09-21
SK15698A3 (en) 1998-06-03
ES2181907T3 (en) 2003-03-01
DE19530884A1 (en) 1997-02-20
CN1080562C (en) 2002-03-13
ATE219368T1 (en) 2002-07-15
AU702706B2 (en) 1999-03-04
NO316424B1 (en) 2004-01-26
DE19530884C2 (en) 1997-07-31
BR9609932A (en) 1999-06-08
IL122826A (en) 2001-11-25
HUP9802450A2 (en) 1999-02-01
CA2228036A1 (en) 1997-02-27
RU2201232C2 (en) 2003-03-27

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