AU4540096A - Basic oxazoline-amide derivatives of ge 2270 and ge 2270-like antibiotics - Google Patents

Basic oxazoline-amide derivatives of ge 2270 and ge 2270-like antibiotics

Info

Publication number
AU4540096A
AU4540096A AU45400/96A AU4540096A AU4540096A AU 4540096 A AU4540096 A AU 4540096A AU 45400/96 A AU45400/96 A AU 45400/96A AU 4540096 A AU4540096 A AU 4540096A AU 4540096 A AU4540096 A AU 4540096A
Authority
AU
Australia
Prior art keywords
pct
amide derivatives
antibiotics
sec
oxazoline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU45400/96A
Other versions
AU693989B2 (en
Inventor
Romeo Ciabatti
Sergio Lociuro
Pierfausto Seneci
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vicuron Pharmaceuticals LLC
Original Assignee
Vicuron Pharmaceuticals LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vicuron Pharmaceuticals LLC filed Critical Vicuron Pharmaceuticals LLC
Publication of AU4540096A publication Critical patent/AU4540096A/en
Application granted granted Critical
Publication of AU693989B2 publication Critical patent/AU693989B2/en
Assigned to VERSICOR INC reassignment VERSICOR INC Alteration of Name(s) in Register under S187 Assignors: BIOSEARCH ITALIA S.P.A.
Assigned to VICURON PHARMACEUTICALS INC. reassignment VICURON PHARMACEUTICALS INC. Request to Amend Deed and Register Assignors: VERSICOR INC
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

PCT No. PCT/EP96/00425 Sec. 371 Date Jul. 31, 1997 Sec. 102(e) Date Jul. 31, 1997 PCT Filed Feb. 1, 1996 PCT Pub. No. WO96/24608 PCT Pub. Date Aug. 15, 1996The present invention refers to basic oxazoline-amide derivatives of GE 2270 and GE 2270-like antibiotics of general formula (I), wherein the group GE represents the antibiotic core molecule. The amide derivatives of antibiotic GE 2270 of formula (I) are antimicrobial agents mainly active against gram positive bacteria. <IMAGE> (I)
AU45400/96A 1995-02-07 1996-02-01 Basic oxazoline-amide derivatives of GE 2270 and GE 2270-like antibiotics Ceased AU693989B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP95101596 1995-02-07
EP95101596 1995-02-07
PCT/EP1996/000425 WO1996024608A1 (en) 1995-02-07 1996-02-01 Basic oxazoline-amide derivatives of ge 2270 and ge 2270-like antibiotics

Publications (2)

Publication Number Publication Date
AU4540096A true AU4540096A (en) 1996-08-27
AU693989B2 AU693989B2 (en) 1998-07-09

Family

ID=8218960

Family Applications (1)

Application Number Title Priority Date Filing Date
AU45400/96A Ceased AU693989B2 (en) 1995-02-07 1996-02-01 Basic oxazoline-amide derivatives of GE 2270 and GE 2270-like antibiotics

Country Status (13)

Country Link
US (1) US5891869A (en)
EP (1) EP0808326B1 (en)
JP (1) JP3518606B2 (en)
KR (1) KR100394930B1 (en)
AT (1) ATE205505T1 (en)
AU (1) AU693989B2 (en)
CA (1) CA2212437A1 (en)
DE (1) DE69615155T2 (en)
DK (1) DK0808326T3 (en)
ES (1) ES2161344T3 (en)
PT (1) PT808326E (en)
SI (1) SI0808326T1 (en)
WO (1) WO1996024608A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU714958B2 (en) * 1996-02-14 2000-01-13 Vicuron Pharmaceuticals Inc. Derivatives of antibiotic GE2270 factors C2a D2 and E

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE165101T1 (en) * 1995-02-07 1998-05-15 Biosearch Italia Spa BASIC PROLINAMIDE DERIVATIVES OF GE2270 AND GE2270-SIMILAR ANTIBIOTICS
US6632812B2 (en) * 2000-04-11 2003-10-14 Dupont Pharmaceuticals Company Substituted lactams as inhibitors of Aβ protein production
WO2004046196A2 (en) * 2002-11-18 2004-06-03 Vicuron Pharmaceuticals Inc. Compositions and methods for treating bacterial infections with protein-dalbavancin complexes
US20060074014A1 (en) * 2002-11-18 2006-04-06 Vicuron Pharmaceuticals Inc. Dalbavancin compositions for treatment of bacterial infections
US7119061B2 (en) * 2002-11-18 2006-10-10 Vicuron Pharmaceuticals, Inc. Dalbavancin compositions for treatment of bacterial infections
US7023707B2 (en) * 2003-01-30 2006-04-04 Endicott Interconnect Technologies, Inc. Information handling system
US7035113B2 (en) * 2003-01-30 2006-04-25 Endicott Interconnect Technologies, Inc. Multi-chip electronic package having laminate carrier and method of making same
US6828514B2 (en) * 2003-01-30 2004-12-07 Endicott Interconnect Technologies, Inc. High speed circuit board and method for fabrication
CA2455024A1 (en) * 2003-01-30 2004-07-30 Endicott Interconnect Technologies, Inc. Stacked chip electronic package having laminate carrier and method of making same
AR060977A1 (en) * 2006-05-31 2008-07-23 Novartis Ag AMINOTIAZOLES AND ITS USES
WO2008082562A2 (en) * 2006-12-20 2008-07-10 Novartis Ag Aminothiazole macrocycles, their use as antibacterial compounds and processes for their production
EA020205B1 (en) 2007-12-12 2014-09-30 Новартис Аг Aminothiazoles, pharmaceutical compositions based thereon and methods for treating bacterial infections

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5202241A (en) * 1988-09-09 1993-04-13 Gruppo Lepetit S.P.A. Antibiotic GE 2270
EP0406745B1 (en) 1989-07-04 1995-01-25 GRUPPO LEPETIT S.p.A. Antibiotic GE 2270 factors A1, A2, A3 and H
DK0451486T3 (en) * 1990-03-08 1995-05-08 Lepetit Spa Antibiotic GE 2270 factors B1, B2, C1, C2, D1, D2, E and T
IL100572A (en) 1991-01-03 1997-01-10 Lepetit Spa Amides of antibiotic ge 2270 factors their preparation and pharmaceutical compositions containing them
EP0529410B1 (en) * 1991-08-30 1998-02-25 Biosearch Italia S.p.A. Antibiotic GE 2270 factor C2a
ATE165101T1 (en) * 1995-02-07 1998-05-15 Biosearch Italia Spa BASIC PROLINAMIDE DERIVATIVES OF GE2270 AND GE2270-SIMILAR ANTIBIOTICS
KR19990082541A (en) * 1996-02-14 1999-11-25 클라우디오 쿼르타 Derivatives of the antibiotics GE2270 C2A, D2 and E

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU714958B2 (en) * 1996-02-14 2000-01-13 Vicuron Pharmaceuticals Inc. Derivatives of antibiotic GE2270 factors C2a D2 and E

Also Published As

Publication number Publication date
JPH10513461A (en) 1998-12-22
EP0808326A1 (en) 1997-11-26
JP3518606B2 (en) 2004-04-12
DK0808326T3 (en) 2001-10-01
KR100394930B1 (en) 2003-12-18
WO1996024608A1 (en) 1996-08-15
KR19980701995A (en) 1998-06-25
DE69615155D1 (en) 2001-10-18
EP0808326B1 (en) 2001-09-12
DE69615155T2 (en) 2002-01-17
US5891869A (en) 1999-04-06
ATE205505T1 (en) 2001-09-15
AU693989B2 (en) 1998-07-09
CA2212437A1 (en) 1996-08-15
SI0808326T1 (en) 2001-12-31
PT808326E (en) 2002-02-28
ES2161344T3 (en) 2001-12-01

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Legal Events

Date Code Title Description
PC Assignment registered

Owner name: VERSICOR INC

Free format text: FORMER OWNER WAS: BIOSEARCH ITALIA S.P.A.

HB Alteration of name in register

Owner name: VICURON PHARMACEUTICALS INC.

Free format text: FORMER NAME WAS: VERSICOR INC