AU674556B2 - A subpopulation of MAC-1 molecules which mediate neutrophil adhesion to ICAM-1 and fibrinogen - Google Patents

A subpopulation of MAC-1 molecules which mediate neutrophil adhesion to ICAM-1 and fibrinogen

Info

Publication number
AU674556B2
AU674556B2 AU54423/94A AU5442394A AU674556B2 AU 674556 B2 AU674556 B2 AU 674556B2 AU 54423/94 A AU54423/94 A AU 54423/94A AU 5442394 A AU5442394 A AU 5442394A AU 674556 B2 AU674556 B2 AU 674556B2
Authority
AU
Australia
Prior art keywords
antibody
mac
atcc
binding
cbrm1
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU54423/94A
Other languages
English (en)
Other versions
AU5442394A (en
Inventor
Michael Diamond
Timothy A. Springer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immune Disease Institute Inc
Original Assignee
Immune Disease Institute Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immune Disease Institute Inc filed Critical Immune Disease Institute Inc
Publication of AU5442394A publication Critical patent/AU5442394A/en
Application granted granted Critical
Publication of AU674556B2 publication Critical patent/AU674556B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70546—Integrin superfamily
    • C07K14/70553—Integrin beta2-subunit-containing molecules, e.g. CD11, CD18
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2845—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU54423/94A 1992-10-09 1993-10-12 A subpopulation of MAC-1 molecules which mediate neutrophil adhesion to ICAM-1 and fibrinogen Ceased AU674556B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US95890492A 1992-10-09 1992-10-09
US96415692A 1992-10-22 1992-10-22
US964156 1992-10-22
PCT/US1993/009777 WO1994008620A1 (en) 1992-10-09 1993-10-12 A subpopulation of mac-1 (cd11b/cd18) molecules which mediate neutrophil adhesion to icam-1 and fibrinogen
US958904 1997-10-28

Publications (2)

Publication Number Publication Date
AU5442394A AU5442394A (en) 1994-05-09
AU674556B2 true AU674556B2 (en) 1997-01-02

Family

ID=27130401

Family Applications (1)

Application Number Title Priority Date Filing Date
AU54423/94A Ceased AU674556B2 (en) 1992-10-09 1993-10-12 A subpopulation of MAC-1 molecules which mediate neutrophil adhesion to ICAM-1 and fibrinogen

Country Status (5)

Country Link
EP (1) EP0670734A4 (de)
JP (1) JPH08502956A (de)
AU (1) AU674556B2 (de)
CA (1) CA2144738A1 (de)
WO (1) WO1994008620A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0788514A1 (de) * 1994-10-25 1997-08-13 Glaxo Group Limited Bindungsreagenzien zur behandlung von entzündlichen, autoimmunen und allergischen krankheiten
NL1001380C2 (nl) * 1995-10-09 1997-04-11 Fuji Photo Film Bv Methode voor het dispergeren van een geëmulgeerd materiaal van het olie-druppeltype in een vloeistoftoevoersysteem en bekledingsmethode waarbij van een dergelijke dispergeermethode gebruik wordt gemaakt.
US5914112A (en) * 1996-01-23 1999-06-22 Genentech, Inc. Anti-CD18 antibodies in stroke
US20020081294A1 (en) 1996-01-23 2002-06-27 Genentech, Inc. Co-administration of a thrombolytic and an anti-CD18 antibody in stroke
US20090291048A1 (en) * 2005-10-25 2009-11-26 Baker Idi Heart And Diabetes Institute Holdings Limited Leukocyte-binding polypeptides and uses thereof
WO2010017083A1 (en) * 2008-08-04 2010-02-11 Wayne State University Methods of treating cancer with cd11b antibodies
MX2014001736A (es) 2011-08-17 2014-03-31 Genentech Inc Inhibicion de angiogenesis en tumores refractarios.
US20150337039A1 (en) * 2014-05-22 2015-11-26 Case Western Reserve University Mac-1 antibodies and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4935234A (en) * 1987-06-11 1990-06-19 Dana-Farber Cancer Institute Method of reducing tissue damage at an inflammatory site using a monoclonal antibody
US5019648A (en) * 1987-07-06 1991-05-28 Dana-Farber Cancer Institute Monoclonal antibody specific for the adhesion function domain of a phagocyte cell surface protein
EP0364690A3 (de) * 1988-08-23 1990-07-18 Dana Farber Cancer Institute Alpha-Subeinheit des Mac-1-Leukocyt-Adhäsions-Rezeptors
WO1990003400A1 (en) * 1988-09-28 1990-04-05 Dana-Farber Cancer Institute Intercellular adhesion molecules, and their binding ligands
US5288854A (en) * 1990-11-28 1994-02-22 Center For Blood Research, Inc. Functional derivatives of ICAM-1 which are substantially capable of binding to LFA-1 but are substantially incapable of binding to MAC-1

Also Published As

Publication number Publication date
JPH08502956A (ja) 1996-04-02
CA2144738A1 (en) 1994-04-28
AU5442394A (en) 1994-05-09
EP0670734A1 (de) 1995-09-13
EP0670734A4 (de) 1998-01-14
WO1994008620A1 (en) 1994-04-28

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Publication Publication Date Title
Diamond et al. A subpopulation of Mac-1 (CD11b/CD18) molecules mediates neutrophil adhesion to ICAM-1 and fibrinogen.
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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired