AU6563086A - Process for the preparation of a rabies vaccine and vaccine obtained by this process - Google Patents
Process for the preparation of a rabies vaccine and vaccine obtained by this processInfo
- Publication number
- AU6563086A AU6563086A AU65630/86A AU6563086A AU6563086A AU 6563086 A AU6563086 A AU 6563086A AU 65630/86 A AU65630/86 A AU 65630/86A AU 6563086 A AU6563086 A AU 6563086A AU 6563086 A AU6563086 A AU 6563086A
- Authority
- AU
- Australia
- Prior art keywords
- viruses
- vaccine
- rabies
- nerve tissue
- embryos
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/205—Rhabdoviridae, e.g. rabies virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20111—Lyssavirus, e.g. rabies virus
- C12N2760/20134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Abstract
The rabies vaccine is prepared by growing rabies viruses in animal nerve tissue, mainly in poultry embryos, harvesting the viruses from the nerve tissue or from the heads of the embryos, concentrating the viruses, inactivating them and making up to the vaccine, wherein homogenisation of the nerve tissue or of the embryo heads with a mixer is avoided on harvesting the viruses, and thus damage and fragmentation of the viruses is prevented, in that the nerve tissue or the heads of the embryos or their contents are comminuted without damaging cells, the complete, live and viable viruses are washed out of the resulting cell suspension, the resulting virus suspension is concentrated, delipidated by extraction with an organic solvent which is immiscible with water, and then further selectively concentrated. A myelin-free rabies vaccine is obtained from poultry embryo head tissue containing rabies viruses by the process described above.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH04999/85 | 1985-11-22 | ||
| CH499985 | 1985-11-22 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU6563086A true AU6563086A (en) | 1987-05-28 |
| AU593041B2 AU593041B2 (en) | 1990-02-01 |
Family
ID=4286207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU65630/86A Ceased AU593041B2 (en) | 1985-11-22 | 1986-11-21 | Process for the preparation of a rabies vaccine and vaccine obtained by this process |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0222974B1 (en) |
| JP (1) | JPS62129225A (en) |
| AT (1) | ATE69383T1 (en) |
| AU (1) | AU593041B2 (en) |
| CA (1) | CA1271708A (en) |
| DE (1) | DE3682482D1 (en) |
| ES (1) | ES2000065A6 (en) |
| PT (1) | PT83543B (en) |
| ZA (1) | ZA866846B (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPN030794A0 (en) | 1994-12-22 | 1995-01-27 | Aruba International Pty Ltd | Discontinuous plasma or serum delipidation |
| AUPQ486699A0 (en) * | 1999-12-23 | 2000-02-03 | Aruba International Pty Ltd | A method of treating infectious diseases |
| US20090017069A1 (en) | 2000-06-29 | 2009-01-15 | Lipid Sciences, Inc. | SARS Vaccine Compositions and Methods of Making and Using Them |
| AUPQ846900A0 (en) * | 2000-06-29 | 2000-07-27 | Aruba International Pty Ltd | A vaccine |
| JP2007524383A (en) * | 2003-06-20 | 2007-08-30 | リピッド サイエンシーズ，インコーポレイテッド | Modified virus particles with reduced lipid content with immunogenic properties useful for treating and preventing infectious diseases |
| US7393826B2 (en) | 2003-07-03 | 2008-07-01 | Lipid Sciences, Inc. | Methods and apparatus for creating particle derivatives of HDL with reduced lipid content |
| DK2368565T3 (en) * | 2003-07-03 | 2015-09-28 | Hdl Therapeutics Inc | Enrichment of pre-beta lipoproteins, high density |
| EP3714039A4 (en) | 2017-11-22 | 2021-07-28 | HDL Therapeutics, Inc. | Systems and methods for priming fluid circuits of a plasma processing system |
| CA3087207A1 (en) | 2017-12-28 | 2019-07-04 | Hdl Therapeutics, Inc. | Methods for preserving and administering pre-beta high density lipoprotein extracted from human plasma |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3143470A (en) * | 1961-04-24 | 1964-08-04 | Parke Davis & Co | Rabies virus propagation in embryonic cells maintained in a medium containing pancreatic digest of casein |
| CH638985A5 (en) * | 1979-04-10 | 1983-10-31 | Schweiz Serum & Impfinst | METHOD FOR THE PRODUCTION OF A RABBIT VACCINE AND THE Vaccine OBTAINED THEREFORE. |
| US4347239A (en) * | 1980-07-30 | 1982-08-31 | Norden Laboratories, Inc. | Inactivated rabies vaccine for veterinary use |
-
1986
- 1986-07-23 EP EP86110116A patent/EP0222974B1/en not_active Expired - Lifetime
- 1986-07-23 DE DE8686110116T patent/DE3682482D1/en not_active Expired - Lifetime
- 1986-07-23 AT AT86110116T patent/ATE69383T1/en not_active IP Right Cessation
- 1986-07-30 ES ES8600731A patent/ES2000065A6/en not_active Expired
- 1986-09-05 CA CA000517612A patent/CA1271708A/en not_active Expired - Lifetime
- 1986-09-09 ZA ZA866846A patent/ZA866846B/en unknown
- 1986-10-14 PT PT83543A patent/PT83543B/en unknown
- 1986-11-21 JP JP61276881A patent/JPS62129225A/en active Granted
- 1986-11-21 AU AU65630/86A patent/AU593041B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| PT83543A (en) | 1986-11-01 |
| CA1271708A (en) | 1990-07-17 |
| DE3682482D1 (en) | 1991-12-19 |
| ATE69383T1 (en) | 1991-11-15 |
| EP0222974A3 (en) | 1989-06-14 |
| ES2000065A6 (en) | 1987-11-16 |
| EP0222974A2 (en) | 1987-05-27 |
| JPS62129225A (en) | 1987-06-11 |
| JPH0586934B2 (en) | 1993-12-14 |
| PT83543B (en) | 1988-11-30 |
| EP0222974B1 (en) | 1991-11-13 |
| ZA866846B (en) | 1987-04-29 |
| AU593041B2 (en) | 1990-02-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |