AU645981B2 - Removal of human anti-murine and heterophilic antibody interference in double antibody EIA assays - Google Patents

Removal of human anti-murine and heterophilic antibody interference in double antibody EIA assays Download PDF

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Publication number
AU645981B2
AU645981B2 AU59652/90A AU5965290A AU645981B2 AU 645981 B2 AU645981 B2 AU 645981B2 AU 59652/90 A AU59652/90 A AU 59652/90A AU 5965290 A AU5965290 A AU 5965290A AU 645981 B2 AU645981 B2 AU 645981B2
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AU
Australia
Prior art keywords
cea
eia
migg
plasma
assay
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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AU59652/90A
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English (en)
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AU5965290A (en
Inventor
Barbara G Beatty
John David Beatty
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City of Hope
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City of Hope
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Publication date
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Publication of AU5965290A publication Critical patent/AU5965290A/en
Application granted granted Critical
Publication of AU645981B2 publication Critical patent/AU645981B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57565—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving carcinoembryonic antigen [CEA]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU59652/90A 1990-04-25 1990-04-25 Removal of human anti-murine and heterophilic antibody interference in double antibody EIA assays Expired - Fee Related AU645981B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1990/002239 WO1991016627A1 (en) 1990-04-25 1990-04-25 Removal of human anti-murine and heterophilic antibody interference in double antibody eia assays

Publications (2)

Publication Number Publication Date
AU5965290A AU5965290A (en) 1991-11-11
AU645981B2 true AU645981B2 (en) 1994-02-03

Family

ID=22220815

Family Applications (1)

Application Number Title Priority Date Filing Date
AU59652/90A Expired - Fee Related AU645981B2 (en) 1990-04-25 1990-04-25 Removal of human anti-murine and heterophilic antibody interference in double antibody EIA assays

Country Status (4)

Country Link
EP (1) EP0479901A1 (enExample)
JP (1) JPH04506866A (enExample)
AU (1) AU645981B2 (enExample)
WO (1) WO1991016627A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3900534A1 (de) * 1989-01-10 1990-07-12 Boehringer Mannheim Gmbh Diagnostischer nachweis unter verwendung von chimaeren antikoerpern
DE69217957T2 (de) * 1991-07-26 1997-08-07 Dade Chemistry Systems Inc Verfahren zur beseitigung von falschen ergebnissen in einem immunoassay
DE19828466A1 (de) 1998-06-26 1999-12-30 Roche Diagnostics Gmbh Entstörung von Immunoassays durch Substanzen, die aus den Framework-Regionen von Antikörpern abgeleitet sind
US20040018556A1 (en) * 2002-07-29 2004-01-29 Cantor Thomas L. Reagent and method for determination of a substance using an immunoaggregator
US8592219B2 (en) 2005-01-17 2013-11-26 Gyros Patent Ab Protecting agent
WO2006075964A1 (en) * 2005-01-17 2006-07-20 Gyros Patent Ab A method for co-transporting a reactant with an amphiphilic macromolecular substans in a microfluid transport conduit
EP1957532A4 (en) * 2005-11-21 2009-11-11 Univ Oregon Health & Science METHOD AND REAGENT FOR ELIMINATING OR REDUCING WRONG POSITIVE RESULTS IN THE ANALYSIS OF A SAMPLE
JP4657328B2 (ja) * 2008-07-18 2011-03-23 栄研化学株式会社 免疫反応干渉物質の除去方法
CN101963618B (zh) * 2010-08-31 2014-03-12 上海铭源数康生物芯片有限公司 在抗体微阵列系统中识别异嗜性抗体干扰的方法及应用其检测目标抗原的抗体微阵列芯片
JP7060510B2 (ja) * 2016-09-06 2022-04-26 富士レビオ株式会社 腫瘍マーカーの測定方法及び測定試薬
CN113663646A (zh) * 2021-07-19 2021-11-19 中国计量大学 一种宽谱特异性抗体修饰的磁性金属有机骨架材料的制备方法与应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4818709A (en) * 1983-01-21 1989-04-04 Primus Frederick J CEA-family antigens, Anti-CEA antibodies and CEA immunoassay
US4900684A (en) * 1987-06-01 1990-02-13 Immunomedics, Inc. CEA immunoassay free of human anti-mouse antibody false positives
CA2093494A1 (en) * 1992-04-17 1993-10-18 Keisuke Iwata Method for the elimination of non-specific reactions in immuno-assays

Also Published As

Publication number Publication date
WO1991016627A1 (en) 1991-10-31
JPH04506866A (ja) 1992-11-26
AU5965290A (en) 1991-11-11
EP0479901A1 (en) 1992-04-15
EP0479901A4 (enExample) 1994-03-30

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