AU6403700A - Methods for enhancing the production of cytokines in cell culture - Google Patents

Methods for enhancing the production of cytokines in cell culture Download PDF

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Publication number
AU6403700A
AU6403700A AU64037/00A AU6403700A AU6403700A AU 6403700 A AU6403700 A AU 6403700A AU 64037/00 A AU64037/00 A AU 64037/00A AU 6403700 A AU6403700 A AU 6403700A AU 6403700 A AU6403700 A AU 6403700A
Authority
AU
Australia
Prior art keywords
cytokine
expression
cells
pkr
cell line
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU64037/00A
Other languages
English (en)
Inventor
Laura Browning
Allan S. Lau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genetrol Biotherapeutics Inc
Original Assignee
Genetrol Biotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetrol Biotherapeutics Inc filed Critical Genetrol Biotherapeutics Inc
Publication of AU6403700A publication Critical patent/AU6403700A/en
Assigned to GENETROL BIOTHERAPEUTICS, INC. reassignment GENETROL BIOTHERAPEUTICS, INC. Amend patent request/document other than specification (104) Assignors: GENE TROL BIO THERAPEUTICS
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU64037/00A 1999-06-15 2000-06-14 Methods for enhancing the production of cytokines in cell culture Abandoned AU6403700A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13931399P 1999-06-15 1999-06-15
US60139313 1999-06-15
PCT/US2000/040199 WO2000077236A2 (en) 1999-06-15 2000-06-14 Methods for enhancing the production of cytokines in cell cultur e

Publications (1)

Publication Number Publication Date
AU6403700A true AU6403700A (en) 2001-01-02

Family

ID=22486056

Family Applications (1)

Application Number Title Priority Date Filing Date
AU64037/00A Abandoned AU6403700A (en) 1999-06-15 2000-06-14 Methods for enhancing the production of cytokines in cell culture

Country Status (7)

Country Link
EP (1) EP1255848A2 (de)
JP (1) JP2003509012A (de)
CN (1) CN1399681A (de)
AU (1) AU6403700A (de)
CA (1) CA2376487A1 (de)
HK (1) HK1048650A1 (de)
WO (1) WO2000077236A2 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010031859A1 (en) * 1999-09-08 2001-10-18 Lau Allan S. High level cytokine production with enhanced cell viability
US20020150552A1 (en) * 2000-09-12 2002-10-17 Lau Allan S. Compositions comprising mixtures of therapeutic proteins and methods of producing the same
US6864061B2 (en) 2000-09-14 2005-03-08 Genetrol Biotherapeutics, Inc. Method for screening compounds for anti-inflammatory activity
JP2005500816A (ja) * 2000-12-19 2005-01-13 ジーントロール バイオセラピューティクス， インコーポレイテッド サイトカイン産生を増加するための増大したｐｋｒ発現を有する細胞
JP2008528006A (ja) * 2005-01-28 2008-07-31 アポロ ライフ サイエンシズ リミテッド 分子およびそのキメラ分子
EP2625577B1 (de) 2010-10-08 2019-06-26 Terumo BCT, Inc. Anpassbares verfahren und systeme für züchtung und ernte von zellen in einem hohlfaser-bioreaktorsystem
JP6633522B2 (ja) 2013-11-16 2020-01-22 テルモ ビーシーティー、インコーポレーテッド バイオリアクターにおける細胞増殖
WO2015148704A1 (en) 2014-03-25 2015-10-01 Terumo Bct, Inc. Passive replacement of media
WO2016049421A1 (en) 2014-09-26 2016-03-31 Terumo Bct, Inc. Scheduled feed
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
US11965175B2 (en) 2016-05-25 2024-04-23 Terumo Bct, Inc. Cell expansion
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
EP3562936B1 (de) * 2017-01-02 2024-05-22 F. Hoffmann-La Roche AG Verfahren zur kultivierung von b-zellen
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
EP3656841A1 (de) 2017-03-31 2020-05-27 Terumo BCT, Inc. Zellexpansion
US12043823B2 (en) 2021-03-23 2024-07-23 Terumo Bct, Inc. Cell capture and expansion

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5641670A (en) * 1991-11-05 1997-06-24 Transkaryotic Therapies, Inc. Protein production and protein delivery
AU3780593A (en) * 1992-02-28 1993-09-13 Beth Israel Hospital Association, The Methods and compounds for prevention of graft rejection
US5840565A (en) * 1995-08-22 1998-11-24 The Regents Of The University Of California Methods for enhancing the production of viral vaccines in PKR-deficient cell culture

Also Published As

Publication number Publication date
CN1399681A (zh) 2003-02-26
HK1048650A1 (zh) 2003-04-11
EP1255848A2 (de) 2002-11-13
WO2000077236A3 (en) 2002-09-12
CA2376487A1 (en) 2000-12-21
WO2000077236A2 (en) 2000-12-21
JP2003509012A (ja) 2003-03-11

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Legal Events

Date Code Title Description
TC Change of applicant's name (sec. 104)

Owner name: GENETROL BIOTHERAPEUTICS, INC.

Free format text: FORMER NAME: GENE TROL BIO THERAPEUTICS