AU6263601A - Antibody and t-cell receptor libraries - Google Patents

Antibody and t-cell receptor libraries

Info

Publication number
AU6263601A
AU6263601A AU62636/01A AU6263601A AU6263601A AU 6263601 A AU6263601 A AU 6263601A AU 62636/01 A AU62636/01 A AU 62636/01A AU 6263601 A AU6263601 A AU 6263601A AU 6263601 A AU6263601 A AU 6263601A
Authority
AU
Australia
Prior art keywords
antibody
cell receptor
receptor libraries
libraries
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU62636/01A
Inventor
Gideon Gross
Yaaqov Schlesinger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GALIM - GALIL IMMUNOLOGY Ltd
Original Assignee
GALIM GALIL IMMUNOLOGY Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GALIM GALIL IMMUNOLOGY Ltd filed Critical GALIM GALIL IMMUNOLOGY Ltd
Publication of AU6263601A publication Critical patent/AU6263601A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU62636/01A 2000-05-30 2001-05-30 Antibody and t-cell receptor libraries Abandoned AU6263601A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL13645900A IL136459A0 (en) 2000-05-30 2000-05-30 Antibody library
IL136459 2000-05-30
PCT/IL2001/000496 WO2001092291A2 (en) 2000-05-30 2001-05-30 Antibody and t-cell receptor libraries

Publications (1)

Publication Number Publication Date
AU6263601A true AU6263601A (en) 2001-12-11

Family

ID=11074201

Family Applications (1)

Application Number Title Priority Date Filing Date
AU62636/01A Abandoned AU6263601A (en) 2000-05-30 2001-05-30 Antibody and t-cell receptor libraries

Country Status (3)

Country Link
AU (1) AU6263601A (en)
IL (1) IL136459A0 (en)
WO (1) WO2001092291A2 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002359913A1 (en) * 2001-12-20 2003-07-09 Agricultural Research Council Semi-synthetic antibody fragment combinatorial library based on avian immunoglobulin genes
CA2505558C (en) 2002-11-09 2013-07-02 Avidex Limited T cell receptor display
TWI333977B (en) 2003-09-18 2010-12-01 Symphogen As Method for linking sequences of interest
GB0411771D0 (en) * 2004-05-26 2004-06-30 Avidex Ltd Nucleoproteins displaying native T cell receptor libraries
WO2006036445A2 (en) 2004-09-24 2006-04-06 Trustees Of Dartmouth College Chimeric nk receptor and methods for treating cancer
AU2005295033B2 (en) * 2004-10-08 2012-01-19 Virxsys Corporation Targeted trans-splicing of highly abundant transcripts for in vivo production of recombinant proteins
AU2005326784B2 (en) * 2004-10-08 2012-03-15 Virxsys Corporation Use of RNA trans-splicing for antibody gene transfer and antibody polypeptide production
ES2543629T3 (en) * 2006-05-17 2015-08-20 Hoffmann-La Roche Ag Polypeptide producing cells
KR20090118993A (en) 2007-03-01 2009-11-18 심포젠 에이/에스 Method for cloning cognate antibodies
MX2011012696A (en) 2009-05-29 2012-03-29 Morphosys Ag A collection and methods for its use.
WO2011059836A2 (en) 2009-10-29 2011-05-19 Trustees Of Dartmouth College T cell receptor-deficient t cell compositions
US9273283B2 (en) 2009-10-29 2016-03-01 The Trustees Of Dartmouth College Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
EP2528944B1 (en) 2010-01-29 2015-08-12 MorphoSys AG Rodent combinatorial antibody libraries
SG189950A1 (en) 2010-11-19 2013-06-28 Morphosys Ag A collection and methods for its use
WO2013033626A2 (en) 2011-08-31 2013-03-07 Trustees Of Dartmouth College Nkp30 receptor targeted therapeutics
CN110511278A (en) 2012-05-07 2019-11-29 达特茅斯大学理事会 Anti- B7-H6 antibody, fusion protein and its application method
EP3164492B1 (en) * 2014-07-03 2019-10-23 F. Hoffmann-La Roche AG Polypeptide expression systems
WO2016193299A1 (en) * 2015-06-01 2016-12-08 Medigene Immunotherapies Gmbh T cell receptor library
AU2016273214B2 (en) 2015-06-01 2018-10-18 Medigene Immunotherapies Gmbh Method for generating antibodies against T cell receptor
DK3394247T3 (en) 2015-12-23 2021-04-12 Medigene Immunotherapies Gmbh NEW GENERATION OF ANTIGEN-SPECIFIC TCRs
EP3472198B1 (en) 2016-09-29 2020-03-04 H. Hoffnabb-La Roche Ag Improved method for selecting polypeptide producing cells

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6673986B1 (en) * 1990-01-12 2004-01-06 Abgenix, Inc. Generation of xenogeneic antibodies
US5874299A (en) * 1990-08-29 1999-02-23 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies

Also Published As

Publication number Publication date
IL136459A0 (en) 2001-06-14
WO2001092291A2 (en) 2001-12-06
WO2001092291A3 (en) 2002-05-16

Similar Documents

Publication Publication Date Title
AU6263601A (en) Antibody and t-cell receptor libraries
AU2002314433A1 (en) Ephrin-tie receptor materials and methods
AU2001236177A1 (en) T cell receptor libraries
AU2001287180A1 (en) Microarray detector and synthesizer
AU2001271714A1 (en) B7-like polynucleotides, polypeptides, and antibodies
AU2001234125A1 (en) Antibody library
AU2001228665A1 (en) Toll-like receptor
AU2002220843A1 (en) Humanised antibodies and uses thereof
AU2002210917A1 (en) Degraded TPO agonist antibody
AU2001273032A1 (en) Cytokine receptor zcytor17
AU2002255451A1 (en) Procaryotic libraries and uses
AU2001246934A1 (en) Agonist antibodies
AU2002223350A1 (en) Cytokine receptor binding peptides
AU2002219318A1 (en) System and methord for combinatorial library design
EP1132641A3 (en) Friction device
AU6913100A (en) Notch receptor ligands and uses thereof
IL147507A0 (en) T-cell receptor y and uses thereof
AU3283500A (en) Tumor-associated antigen
AU2001284899A1 (en) Methods and universal monoclonal antibody array
AU2002221132A1 (en) Novel antibody
AU2001223882A1 (en) Receptor
AUPQ563400A0 (en) Novel receptor
AU4940800A (en) Polyketides and their synthesis
AU2001261534A1 (en) The meca-79 antigen and related methods
AU2001273456A1 (en) Soluble immunoglobulin e receptor alpha like molecules

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase