AU605172B2 - Polyesters containing alkylene oxide blocks as drug delivery systems - Google Patents

Polyesters containing alkylene oxide blocks as drug delivery systems Download PDF

Info

Publication number
AU605172B2
AU605172B2 AU77970/87A AU7797087A AU605172B2 AU 605172 B2 AU605172 B2 AU 605172B2 AU 77970/87 A AU77970/87 A AU 77970/87A AU 7797087 A AU7797087 A AU 7797087A AU 605172 B2 AU605172 B2 AU 605172B2
Authority
AU
Australia
Prior art keywords
block
polymer
peo
copolymer
gly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU77970/87A
Other languages
English (en)
Other versions
AU7797087A (en
Inventor
Donald James Casey
Peter Kendrick Jarrett
Louis Rosati
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/903,797 external-priority patent/US4716203A/en
Priority claimed from US06/903,801 external-priority patent/US4882168A/en
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of AU7797087A publication Critical patent/AU7797087A/en
Application granted granted Critical
Publication of AU605172B2 publication Critical patent/AU605172B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/64—Polyesters containing both carboxylic ester groups and carbonate groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Materials For Medical Uses (AREA)
AU77970/87A 1986-09-05 1987-09-04 Polyesters containing alkylene oxide blocks as drug delivery systems Ceased AU605172B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US06/903,797 US4716203A (en) 1986-09-05 1986-09-05 Diblock and triblock copolymers
US903801 1986-09-05
US903797 1986-09-05
US06/903,801 US4882168A (en) 1986-09-05 1986-09-05 Polyesters containing alkylene oxide blocks as drug delivery systems

Publications (2)

Publication Number Publication Date
AU7797087A AU7797087A (en) 1988-03-10
AU605172B2 true AU605172B2 (en) 1991-01-10

Family

ID=27129378

Family Applications (1)

Application Number Title Priority Date Filing Date
AU77970/87A Ceased AU605172B2 (en) 1986-09-05 1987-09-04 Polyesters containing alkylene oxide blocks as drug delivery systems

Country Status (13)

Country Link
EP (1) EP0258780B1 (https=)
KR (1) KR880003985A (https=)
AU (1) AU605172B2 (https=)
BR (1) BR8704648A (https=)
CA (1) CA1283988C (https=)
DE (1) DE3786309T2 (https=)
DK (1) DK462287A (https=)
ES (1) ES2058081T3 (https=)
FI (1) FI873840L (https=)
GR (1) GR3008526T3 (https=)
HU (1) HU205711B (https=)
IL (1) IL83764A (https=)
NZ (1) NZ221647A (https=)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL9401703A (nl) * 1994-10-14 1996-05-01 Rijksuniversiteit Kauwgom.
US5702717A (en) * 1995-10-25 1997-12-30 Macromed, Inc. Thermosensitive biodegradable polymers based on poly(ether-ester)block copolymers
US5665428A (en) * 1995-10-25 1997-09-09 Macromed, Inc. Preparation of peptide containing biodegradable microspheres by melt process
DE19726412A1 (de) * 1997-06-21 1998-12-24 Merck Patent Gmbh Implantatmaterial mit einer Träger-Wirkstoff-Kombination
US6201072B1 (en) * 1997-10-03 2001-03-13 Macromed, Inc. Biodegradable low molecular weight triblock poly(lactide-co- glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
EP1034207B1 (en) * 1997-10-03 2005-03-02 Macromed Inc. BIODEGRADABLE LOW MOLECULAR WEIGHT TRIBLOCK POLY(LACTIDE-co-GLYCOLIDE) POLYETHYLENE GLYCOL COPOLYMERS HAVING REVERSE THERMAL GELATION PROPERTIES
US6117949A (en) * 1998-10-01 2000-09-12 Macromed, Inc. Biodegradable low molecular weight triblock poly (lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
US6004573A (en) * 1997-10-03 1999-12-21 Macromed, Inc. Biodegradable low molecular weight triblock poly(lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
US7662409B2 (en) 1998-09-25 2010-02-16 Gel-Del Technologies, Inc. Protein matrix materials, devices and methods of making and using thereof
US7018645B1 (en) 2000-04-27 2006-03-28 Macromed, Inc. Mixtures of various triblock polyester polyethylene glycol copolymers having improved gel properties
EA007772B1 (ru) * 2001-03-23 2007-02-27 Гумлинк А/С Разлагаемый заменитель смолы для жевательной резинки
CA2440016C (en) 2001-03-23 2010-12-14 Gumlink A/S Coated degradable chewing gum with improved shelf life and process for preparing same
WO2003000156A1 (en) 2001-06-22 2003-01-03 Southern Biosystems, Inc. Zero-order prolonged release coaxial implants
ES2304501T3 (es) 2002-02-15 2008-10-16 Nektar Therapeutics Al, Corporation Polimeros a base de oxido de alquileno degradables hidroliticamente.
CA2483778A1 (en) 2002-04-29 2003-11-13 Gel-Del Technologies, Inc. Biomatrix structural containment and fixation systems and methods of use thereof
EP1504047B1 (en) * 2002-05-03 2007-12-12 Janssen Pharmaceutica N.V. Polymeric microemulsions
US7649023B2 (en) 2002-06-11 2010-01-19 Novartis Ag Biodegradable block copolymeric compositions for drug delivery
ES2377318T3 (es) 2002-09-06 2012-03-26 Cerulean Pharma Inc. Polímeros a base de ciclodextrina para el suministro de los agentes terapéuticos enlazados covalentemente a ellos
EP1542542B2 (en) 2002-09-24 2013-09-04 Gumlink A/S Biodegradable chewing gum comprising at least one high molecular weight biodegradable polymer
CA2500976A1 (en) 2002-09-24 2004-04-08 Gumlink A/S Chewing gum comprising at least two different biodegradable polymers
EP1474993B1 (en) 2003-05-06 2008-08-20 Gumlink A/S A method for producing chewing gum granules and compressed gum products, and a chewing gum granulating system
EP1474995B1 (en) 2003-05-06 2012-11-14 Gumlink A/S A method for producing chewing gum granules, a gum composition extruder and granulating system, and a chewing gum product
US8465537B2 (en) 2003-06-17 2013-06-18 Gel-Del Technologies, Inc. Encapsulated or coated stent systems
WO2005034852A2 (en) 2003-08-26 2005-04-21 Gel-Del Technologies, Inc. Protein biomaterials and biocoacervates and methods of making and using thereof
WO2005055945A2 (en) 2003-12-08 2005-06-23 Gel-Del Technologies, Inc. Mucoadhesive drug delivery devices and methods of making and using thereof
US20080176958A1 (en) 2007-01-24 2008-07-24 Insert Therapeutics, Inc. Cyclodextrin-based polymers for therapeutics delivery
CA2711001A1 (en) 2007-12-26 2009-07-09 Gel-Del Technologies, Inc. Biocompatible protein-based particles and methods thereof
US10016534B2 (en) 2008-11-17 2018-07-10 Gel-Del Technologies, Inc. Protein biomaterial and biocoacervate vessel graft systems and methods of making and using thereof
AU2010295646B2 (en) 2009-09-15 2016-02-11 Ellipses Pharma Limited Treatment of cancer
US20110300150A1 (en) 2010-05-18 2011-12-08 Scott Eliasof Compositions and methods for treatment of autoimmune and other disease
US20140094432A1 (en) 2012-10-02 2014-04-03 Cerulean Pharma Inc. Methods and systems for polymer precipitation and generation of particles
EP4192509A1 (en) 2020-08-05 2023-06-14 Ellipses Pharma Ltd Treatment of cancer using a cyclodextrin-containing polymer-topoisomerase inhibitor conjugate and a parp inhibitor

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4047533A (en) * 1976-09-20 1977-09-13 American Cyanamid Company Absorbable surgical sutures coated with polyoxyethylene-polyoxypropylene copolymer lubricant
US4438253A (en) * 1982-11-12 1984-03-20 American Cyanamid Company Poly(glycolic acid)/poly(alkylene glycol) block copolymers and method of manufacturing the same
US4452973A (en) * 1982-11-12 1984-06-05 American Cyanamid Company Poly(glycolic acid)/poly(oxyethylene) triblock copolymers and method of manufacturing the same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3736646A (en) * 1971-10-18 1973-06-05 American Cyanamid Co Method of attaching surgical needles to multifilament polyglycolic acid absorbable sutures
US4429080A (en) * 1982-07-01 1984-01-31 American Cyanamid Company Synthetic copolymer surgical articles and method of manufacturing the same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4047533A (en) * 1976-09-20 1977-09-13 American Cyanamid Company Absorbable surgical sutures coated with polyoxyethylene-polyoxypropylene copolymer lubricant
US4438253A (en) * 1982-11-12 1984-03-20 American Cyanamid Company Poly(glycolic acid)/poly(alkylene glycol) block copolymers and method of manufacturing the same
US4452973A (en) * 1982-11-12 1984-06-05 American Cyanamid Company Poly(glycolic acid)/poly(oxyethylene) triblock copolymers and method of manufacturing the same

Also Published As

Publication number Publication date
NZ221647A (en) 1990-09-26
DK462287A (da) 1988-03-06
CA1283988C (en) 1991-05-07
HU205711B (en) 1992-06-29
ES2058081T3 (es) 1994-11-01
IL83764A (en) 1991-05-12
EP0258780A2 (en) 1988-03-09
HUT52945A (en) 1990-09-28
FI873840A0 (fi) 1987-09-04
EP0258780A3 (en) 1988-05-18
IL83764A0 (en) 1988-02-29
AU7797087A (en) 1988-03-10
DE3786309T2 (de) 1994-02-10
EP0258780B1 (en) 1993-06-23
KR880003985A (ko) 1988-05-31
DK462287D0 (da) 1987-09-04
GR3008526T3 (https=) 1993-10-29
FI873840A7 (fi) 1988-03-06
BR8704648A (pt) 1988-04-26
DE3786309D1 (de) 1993-07-29
FI873840L (fi) 1988-03-06

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