AU5958196A - Novel base protecting groups for oligonucleotide synthesis - Google Patents
Novel base protecting groups for oligonucleotide synthesisInfo
- Publication number
- AU5958196A AU5958196A AU59581/96A AU5958196A AU5958196A AU 5958196 A AU5958196 A AU 5958196A AU 59581/96 A AU59581/96 A AU 59581/96A AU 5958196 A AU5958196 A AU 5958196A AU 5958196 A AU5958196 A AU 5958196A
- Authority
- AU
- Australia
- Prior art keywords
- protecting groups
- oligonucleotide synthesis
- novel base
- base protecting
- novel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000002515 oligonucleotide synthesis Methods 0.000 title 1
- 125000006239 protecting group Chemical group 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US45719895A | 1995-06-01 | 1995-06-01 | |
US457198 | 1995-06-01 | ||
US518921 | 1995-08-24 | ||
US08/518,921 US5614622A (en) | 1995-06-01 | 1995-08-24 | 5-pentenoyl moiety as a nucleoside-amino protecting group, 4-pentenoyl-protected nucleotide synthons, and related oligonucleotide syntheses |
US519318 | 1995-08-25 | ||
US08/519,318 US6140482A (en) | 1995-06-01 | 1995-08-25 | Primary phosphoramidate internucleoside linkages and oligonucleotides containing the same |
US08/570,390 US5955599A (en) | 1995-06-01 | 1995-12-11 | Process for making oligonucleotides containing o- and s- methylphosphotriester internucleoside linkages |
US570390 | 1995-12-11 | ||
US08/598,320 US6531589B1 (en) | 1995-06-01 | 1996-02-08 | Base protecting groups and synthons for oligonucleotide synthesis |
US598320 | 1996-02-08 | ||
US08/606,915 US5962674A (en) | 1995-06-01 | 1996-02-26 | Synthesis of oligonucleotides containing alkylphosphonate internucleoside linkages |
US606915 | 1996-02-26 | ||
PCT/US1996/008136 WO1996039414A1 (en) | 1995-06-01 | 1996-05-31 | Novel base protecting groups for oligonucleotide synthesis |
Publications (1)
Publication Number | Publication Date |
---|---|
AU5958196A true AU5958196A (en) | 1996-12-24 |
Family
ID=23815816
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU59581/96A Abandoned AU5958196A (en) | 1995-06-01 | 1996-05-31 | Novel base protecting groups for oligonucleotide synthesis |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU5958196A (en) |
WO (1) | WO1996039414A1 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6509459B1 (en) * | 1995-06-01 | 2003-01-21 | Hybridon, Inc. | Base protecting groups and rapid process for oligonucleotide synthesis |
AU6141598A (en) * | 1997-02-04 | 1998-08-25 | Hybridon, Inc. | Base protecting groups and process for oligonucleotide synthesis |
DE19741738A1 (en) * | 1997-09-22 | 1999-03-25 | Hoechst Ag | Linker nucleoside(s) containing alkenyloxy or phthalimido-alkyl groups |
DE19741715A1 (en) | 1997-09-22 | 1999-03-25 | Hoechst Ag | New pentopyranosyl nucleoside compounds |
WO2000040592A1 (en) * | 1998-12-30 | 2000-07-13 | Oligos Etc. Inc. | Acid stable backbone modified end-blocked nucleic acids and therapeutic uses thereof |
CN106566855B (en) * | 2006-07-31 | 2021-11-09 | 苏州新海生物科技股份有限公司 | Nucleic acid amplification using reversibly modified oligonucleotides |
US9045522B2 (en) | 2006-07-31 | 2015-06-02 | Wanli Bi | Nucleic acid amplification using a reversibly modified oligonucleotide |
WO2008094640A2 (en) | 2007-01-30 | 2008-08-07 | Geron Corporation | Compounds having anti-adhesive effects on cancer cells |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4959463A (en) * | 1985-10-15 | 1990-09-25 | Genentech, Inc. | Intermediates |
NL8700724A (en) * | 1987-03-27 | 1988-10-17 | Univ Eindhoven Tech | POLY (DEOXYRIBONUCLEOTIDES), PHARMACEUTICAL COMPOSITIONS, USE AND PREPARATION OF THE POLY (DEOXYRIBONUCLEOTIDES). |
CA2121144C (en) * | 1991-10-15 | 2001-07-31 | Phillip Dan Cook | Oligonucleotides having chiral phosphorus linkages |
-
1996
- 1996-05-31 WO PCT/US1996/008136 patent/WO1996039414A1/en active Application Filing
- 1996-05-31 AU AU59581/96A patent/AU5958196A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO1996039414A1 (en) | 1996-12-12 |
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