AU592088B2 - 2,3-dihydro-6-hydroxypyrimido-purine-diones - Google Patents

2,3-dihydro-6-hydroxypyrimido-purine-diones Download PDF

Info

Publication number
AU592088B2
AU592088B2 AU58166/86A AU5816686A AU592088B2 AU 592088 B2 AU592088 B2 AU 592088B2 AU 58166/86 A AU58166/86 A AU 58166/86A AU 5816686 A AU5816686 A AU 5816686A AU 592088 B2 AU592088 B2 AU 592088B2
Authority
AU
Australia
Prior art keywords
carbon atoms
hydroxy
dihydro
compound
dione
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU58166/86A
Other languages
English (en)
Other versions
AU5816686A (en
Inventor
David Jeffry Conn
James Joseph Kaminski
Daniel Mordecai Solomon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of AU5816686A publication Critical patent/AU5816686A/en
Application granted granted Critical
Publication of AU592088B2 publication Critical patent/AU592088B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU58166/86A 1985-05-13 1986-05-12 2,3-dihydro-6-hydroxypyrimido-purine-diones Ceased AU592088B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/732,994 US4666914A (en) 1985-05-13 1985-05-13 Anti-inflammatory and anti-allergic substituted-2,3-dihydro-6-(hydroxy)pyrimido[2,1-f]-purine-4,8(1H,9H)-diones
US732994 1985-05-13

Publications (2)

Publication Number Publication Date
AU5816686A AU5816686A (en) 1986-12-04
AU592088B2 true AU592088B2 (en) 1990-01-04

Family

ID=24945768

Family Applications (1)

Application Number Title Priority Date Filing Date
AU58166/86A Ceased AU592088B2 (en) 1985-05-13 1986-05-12 2,3-dihydro-6-hydroxypyrimido-purine-diones

Country Status (11)

Country Link
US (2) US4666914A (OSRAM)
EP (1) EP0221996B1 (OSRAM)
JP (1) JPS62502842A (OSRAM)
KR (1) KR900004834B1 (OSRAM)
AU (1) AU592088B2 (OSRAM)
CA (1) CA1283103C (OSRAM)
DE (1) DE3673759D1 (OSRAM)
DK (1) DK13487A (OSRAM)
FI (1) FI870079L (OSRAM)
HU (1) HU195221B (OSRAM)
WO (1) WO1986006724A1 (OSRAM)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4666914A (en) * 1985-05-13 1987-05-19 Schering Corporation Anti-inflammatory and anti-allergic substituted-2,3-dihydro-6-(hydroxy)pyrimido[2,1-f]-purine-4,8(1H,9H)-diones
US4847377A (en) * 1985-05-13 1989-07-11 Schering Corporation Substituted-2,3-dihydro-6-substituted-pyrimido[2,1-F]-purine-4,8(1H,9H)-diones
GB8906792D0 (en) * 1989-03-23 1989-05-10 Beecham Wuelfing Gmbh & Co Kg Treatment and compounds
CN102452750B (zh) * 2010-10-15 2013-05-01 中国石油化工股份有限公司 炼油污水分类控制分级处理方法
EP4161903A4 (en) * 2020-06-04 2024-05-22 London Pharmaceuticals and Research Corporation Rigid cannabidiol analogues as potent modulators of cannabinoid receptors and uses thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2042783A (en) * 1982-10-25 1984-05-03 Schering Corporation Substituted 9h-8-oxo-pyrimido(2,1-f)purine-2,4-diones

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3862189A (en) * 1973-08-14 1975-01-21 Warner Lambert Co Aralkyl-substituted purines and pyrimidines as antianginal bronchodilator agents
US4457919A (en) * 1980-03-14 1984-07-03 Newport Pharmaceutical International, Inc. Method of imparting immunomodulating, antiviral or antitumor activity
DE3131365A1 (de) * 1981-08-07 1983-02-24 Henkel KGaA, 4000 Düsseldorf Neue diglycidyl-substituierte heterocyclische verbindungen, verfahren zu ihrer herstellung und ihre verwendung in arzneimittelzubereitungen mit cytostatischer wirksamkeit
US4569936A (en) * 1982-10-25 1986-02-11 Schering Corporation Anti-inflammatory substituted 9H-8-oxo-pyrimido[2,1-f]purine-2,4-diones
US4666914A (en) * 1985-05-13 1987-05-19 Schering Corporation Anti-inflammatory and anti-allergic substituted-2,3-dihydro-6-(hydroxy)pyrimido[2,1-f]-purine-4,8(1H,9H)-diones

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2042783A (en) * 1982-10-25 1984-05-03 Schering Corporation Substituted 9h-8-oxo-pyrimido(2,1-f)purine-2,4-diones

Also Published As

Publication number Publication date
AU5816686A (en) 1986-12-04
CA1283103C (en) 1991-04-16
EP0221996B1 (en) 1990-08-29
JPS62502842A (ja) 1987-11-12
KR870700624A (ko) 1987-12-30
JPH0513953B2 (OSRAM) 1993-02-23
US4666914A (en) 1987-05-19
KR900004834B1 (ko) 1990-07-07
EP0221996A1 (en) 1987-05-20
HU195221B (en) 1988-04-28
FI870079A7 (fi) 1987-01-09
HUT41794A (en) 1987-05-28
DE3673759D1 (de) 1990-10-04
WO1986006724A1 (en) 1986-11-20
FI870079A0 (fi) 1987-01-09
DK13487D0 (da) 1987-01-12
US4816458A (en) 1989-03-28
DK13487A (da) 1987-03-12
FI870079L (fi) 1987-01-09

Similar Documents

Publication Publication Date Title
AU670544B2 (en) Benzo and pyrido pyridazinone and pyridazinthione compounds with PDE IV inhibiting activity
WO1997028161A1 (en) Novel pyrrolo[2,3-d]pyrimidines and their use as tyrosine kinase inhibitors
US3995039A (en) Pyrazolo [1,5-a] [1,3,5] triazines
SK56195A3 (en) Pyrrolopyrimidine derivatives with pharmacologic effeciency
EP0225013A1 (en) Heterocyclic compounds and their preparation and use
JPS6136282A (ja) 窒素を含む複素環式化合物からなる医薬品とその製造方法
US5565463A (en) 9-subtituted-8-unsubstituted-9-deazaguanines
JPS6225150B2 (OSRAM)
KR900005836B1 (ko) 1,2,4-트리아조로[4,3-c]피리미딘
IE66336B1 (en) Imidazoquinoxaline compounds and their preparation and use
AU592088B2 (en) 2,3-dihydro-6-hydroxypyrimido-purine-diones
US4477450A (en) Triazolo [4,3-c]pyrimidines substituted by nitrogen-containing heterocyclic rings
US3993650A (en) Pyrrolo [3,4-d] pyrimidines
US4153796A (en) Hydrazino derivatives of 1H-pyrazolo(3,4-b)-pyridine-5-carboxamides
IE830558L (en) Bicyclic benzo fused compounds
HU192653B (en) Process for the production of imidazo /1,2-c/pyrimidines, as well as of therapeutic preparations containing these compounds as agent
US3931176A (en) Hydroxyalkyl substituted-4,5-dihydropyridazin(2H)-3-ones
US5116841A (en) Imidazoquinoxalines and their preparation and use
CA1175428A (en) Process for preparing imidazo /1,2-a/ quinoline derivatives
JP2651912B2 (ja) イミダゾール誘導体、それらの製造法及び薬剤としての使用
US4847377A (en) Substituted-2,3-dihydro-6-substituted-pyrimido[2,1-F]-purine-4,8(1H,9H)-diones
US4072681A (en) 3,7-Dihydro- and 1,7-dihydro-4H-pyrazolo[4',3':5,6]pyrido[4,3-d]pyrimidin-4-ones
US3962262A (en) 1,8-naphthyridine compounds
CA1225645A (en) Substituted 9h-8-oxo-pyrimido[2,1-f]purine-2,4- diones, process for their production and pharmaceutical compositions containing them
US4569936A (en) Anti-inflammatory substituted 9H-8-oxo-pyrimido[2,1-f]purine-2,4-diones