AU587841B2 - Poly-4-aminopyrrole-2-carboxamido derivatives and process for their preparation - Google Patents

Poly-4-aminopyrrole-2-carboxamido derivatives and process for their preparation

Info

Publication number
AU587841B2
AU587841B2 AU60202/86A AU6020286A AU587841B2 AU 587841 B2 AU587841 B2 AU 587841B2 AU 60202/86 A AU60202/86 A AU 60202/86A AU 6020286 A AU6020286 A AU 6020286A AU 587841 B2 AU587841 B2 AU 587841B2
Authority
AU
Australia
Prior art keywords
aminopyrrole
poly
preparation
carboxamido derivatives
carboxamido
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU60202/86A
Other languages
English (en)
Other versions
AU6020286A (en
Inventor
Federico Arcamone
Nicola Mongelli
Sergio Penco
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858517922A external-priority patent/GB8517922D0/en
Priority claimed from GB868613594A external-priority patent/GB8613594D0/en
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Publication of AU6020286A publication Critical patent/AU6020286A/en
Application granted granted Critical
Publication of AU587841B2 publication Critical patent/AU587841B2/en
Assigned to PHARMACIA & UPJOHN S.P.A. reassignment PHARMACIA & UPJOHN S.P.A. Alteration of Name(s) in Register under S187 Assignors: FARMITALIA CARLO ERBA S.P.A.
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
AU60202/86A 1985-07-16 1986-07-14 Poly-4-aminopyrrole-2-carboxamido derivatives and process for their preparation Ceased AU587841B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8517922 1985-07-16
GB858517922A GB8517922D0 (en) 1985-07-16 1985-07-16 Carboxamido derivatives
GB868613594A GB8613594D0 (en) 1986-06-04 1986-06-04 Poly-4-aminopyrrole-2-carboxamido derivatives
GB8613594 1986-06-04

Publications (2)

Publication Number Publication Date
AU6020286A AU6020286A (en) 1987-01-22
AU587841B2 true AU587841B2 (en) 1989-08-31

Family

ID=26289538

Family Applications (1)

Application Number Title Priority Date Filing Date
AU60202/86A Ceased AU587841B2 (en) 1985-07-16 1986-07-14 Poly-4-aminopyrrole-2-carboxamido derivatives and process for their preparation

Country Status (26)

Country Link
JP (1) JPH0780843B2 (de)
KR (1) KR930010496B1 (de)
CN (1) CN1018825B (de)
AT (1) AT387013B (de)
AU (1) AU587841B2 (de)
BE (1) BE905110A (de)
CA (1) CA1285934C (de)
CH (1) CH674206A5 (de)
CS (1) CS276981B6 (de)
DE (1) DE3623880A1 (de)
DK (1) DK335986A (de)
ES (1) ES2000502A6 (de)
FI (1) FI83640C (de)
FR (1) FR2585018B1 (de)
GB (1) GB2178036B (de)
GR (1) GR861841B (de)
HU (1) HU205949B (de)
IE (1) IE59073B1 (de)
IL (1) IL79402A (de)
IT (1) IT1196488B (de)
NL (1) NL8601837A (de)
NO (1) NO168826C (de)
NZ (1) NZ216829A (de)
PH (1) PH24714A (de)
PT (1) PT82984B (de)
SE (1) SE468642B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN85103908A (zh) * 1985-07-16 1986-11-05 法米塔利·卡洛·埃尔巴有限公司 制备4′-表多克索红菌素的新方法
GB8906709D0 (en) * 1989-03-23 1989-05-10 Creighton Andrew M Acryloyl substituted pyrrole derivatives
IT1243389B (it) * 1990-11-22 1994-06-10 Menarini Farma Ind Derivati poliaminopirrolcarbossiamidici, processi di preparazione e composizioni farmaceutiche che li contengono.
AU1224392A (en) * 1991-02-06 1992-09-07 Synphar Laboratories, Inc. Oligopeptide antiretroviral agents
IT1247878B (it) * 1991-02-15 1995-01-05 Menarini Farma Ind Derivati poli-4-aminopirrol-2-carbossiamidici,processi di preparazione e composizioni farmaceutiche che li contengono
GB2260134A (en) * 1991-10-04 1993-04-07 Erba Carlo Spa Derivatives of poly-5-amino-3-carboxy-1-methyl compounds
IT1262921B (it) * 1992-01-10 1996-07-22 Federico Arcamone Agenti antitumorali analoghi di oligopeptidi pirrol-amidinici retroversi processi di preparazione e prodotti farmaceutici che li contengono
GB9416005D0 (en) * 1994-08-08 1994-09-28 Erba Carlo Spa Peptidic compounds analogous to distamycin a and process for their preparation
CA2204648A1 (en) * 1995-09-12 1997-03-20 Akira Mihara Uch15 compounds
JP2000503999A (ja) * 1996-02-02 2000-04-04 フアルマシア・エ・アツプジヨン・エツセ・ピー・アー ジスタマイシン誘導体、その調製方法、および抗腫瘍および抗ウイルス剤としてのその使用
GB9615692D0 (en) * 1996-07-25 1996-09-04 Pharmacia Spa Acryloyl substituted distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents
GB0011059D0 (en) 2000-05-08 2000-06-28 Pharmacia & Upjohn Spa Use of substituted acryloyl distamycin derivatives in the treatment of tumours associated with high levels of glutathione
GB0015446D0 (en) 2000-06-23 2000-08-16 Pharmacia & Upjohn Spa Combined therapy against tumors comprising substituted acryloyl distamycin derivates,taxanes and/or antimetabolites
GB0015447D0 (en) 2000-06-23 2000-08-16 Pharmacia & Upjohn Spa Combined therapy against tumors comprising substituted acryloyl derivates and alkylating agents
GB0016447D0 (en) 2000-07-04 2000-08-23 Pharmacia & Upjohn Spa Process for preparing distamycin derivatives
US6969592B2 (en) 2001-09-26 2005-11-29 Pharmacia Italia S.P.A. Method for predicting the sensitivity to chemotherapy

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6020386A (en) * 1985-07-16 1987-01-22 Pharmacia & Upjohn S.P.A. Distamycin derivatives and process for their preparation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR86210E (de) 1963-04-04 1966-03-23
DE1795539A1 (de) * 1963-07-26 1972-01-13 Farmaceutici Italia Verfahren zur Herstellung von neuen Pyrrolderivaten und ihren Salzen
BE666612A (de) * 1963-07-26 1965-11-03
BR6461040D0 (pt) * 1963-07-26 1973-08-02 Farmaceutici Italia Processo para preparar novos derivados de pirrol
NL130086C (de) * 1964-07-14 1970-06-15

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6020386A (en) * 1985-07-16 1987-01-22 Pharmacia & Upjohn S.P.A. Distamycin derivatives and process for their preparation

Also Published As

Publication number Publication date
ATA188886A (de) 1988-04-15
KR930010496B1 (ko) 1993-10-25
CN86104787A (zh) 1987-02-18
IL79402A0 (en) 1986-10-31
FR2585018A1 (fr) 1987-01-23
PT82984A (en) 1986-08-01
SE8603098L (sv) 1987-01-17
GB8617292D0 (en) 1986-08-20
AT387013B (de) 1988-11-25
FI862959A0 (fi) 1986-07-16
ES2000502A6 (es) 1988-03-01
NO168826B (no) 1991-12-30
HU205949B (en) 1992-07-28
DK335986A (da) 1987-01-17
CN1018825B (zh) 1992-10-28
IT1196488B (it) 1988-11-16
GR861841B (en) 1986-11-18
FI83640B (fi) 1991-04-30
SE468642B (sv) 1993-02-22
NO168826C (no) 1992-04-08
JPH0780843B2 (ja) 1995-08-30
AU6020286A (en) 1987-01-22
IT8621125A1 (it) 1988-01-15
BE905110A (fr) 1987-01-15
NL8601837A (nl) 1987-02-16
PH24714A (en) 1990-10-01
CS8605412A2 (en) 1991-03-12
IE59073B1 (en) 1994-01-12
NO862860L (no) 1987-01-19
PT82984B (pt) 1989-01-30
HUT43088A (en) 1987-09-28
GB2178036A (en) 1987-02-04
GB2178036B (en) 1989-08-16
IL79402A (en) 1991-06-10
IT8621125A0 (it) 1986-07-15
FI83640C (fi) 1991-08-12
DK335986D0 (da) 1986-07-15
CA1285934C (en) 1991-07-09
KR870001201A (ko) 1987-03-12
JPS6277362A (ja) 1987-04-09
FR2585018B1 (fr) 1989-07-13
CH674206A5 (de) 1990-05-15
NZ216829A (en) 1989-03-29
NO862860D0 (no) 1986-07-15
SE8603098D0 (sv) 1986-07-11
CS276981B6 (en) 1992-11-18
IE861875L (en) 1987-01-16
DE3623880A1 (de) 1987-01-29
FI862959A (fi) 1987-01-17

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