AU576390B2 - Indoleacetic acid derivative for use as antiinflammatory and analgesic agents - Google Patents

Indoleacetic acid derivative for use as antiinflammatory and analgesic agents

Info

Publication number
AU576390B2
AU576390B2 AU48573/85A AU4857385A AU576390B2 AU 576390 B2 AU576390 B2 AU 576390B2 AU 48573/85 A AU48573/85 A AU 48573/85A AU 4857385 A AU4857385 A AU 4857385A AU 576390 B2 AU576390 B2 AU 576390B2
Authority
AU
Australia
Prior art keywords
antiinflammatory
acid derivative
analgesic agents
indoleacetic acid
indometacin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU48573/85A
Other languages
English (en)
Other versions
AU4857385A (en
Inventor
Chikara Fukaya
Shuichi Hanada
Youichiro Naito
Masahiro Watanabe
Kazumasa Yokoyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Pharma Corp
Original Assignee
Green Cross Corp Japan
Green Cross Corp Korea
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Green Cross Corp Japan, Green Cross Corp Korea filed Critical Green Cross Corp Japan
Publication of AU4857385A publication Critical patent/AU4857385A/en
Application granted granted Critical
Publication of AU576390B2 publication Critical patent/AU576390B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AU48573/85A 1984-10-22 1985-10-14 Indoleacetic acid derivative for use as antiinflammatory and analgesic agents Ceased AU576390B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59222452A JPS61100565A (ja) 1984-10-22 1984-10-22 インド−ル酢酸誘導体
JP59-222452 1984-10-22

Publications (2)

Publication Number Publication Date
AU4857385A AU4857385A (en) 1986-05-01
AU576390B2 true AU576390B2 (en) 1988-08-25

Family

ID=16782628

Family Applications (1)

Application Number Title Priority Date Filing Date
AU48573/85A Ceased AU576390B2 (en) 1984-10-22 1985-10-14 Indoleacetic acid derivative for use as antiinflammatory and analgesic agents

Country Status (10)

Country Link
US (1) US4868201A (esLanguage)
EP (1) EP0179428B1 (esLanguage)
JP (1) JPS61100565A (esLanguage)
KR (1) KR860003218A (esLanguage)
AT (1) ATE41867T1 (esLanguage)
AU (1) AU576390B2 (esLanguage)
CA (1) CA1287625C (esLanguage)
DE (1) DE3569196D1 (esLanguage)
ES (1) ES8703423A1 (esLanguage)
ZA (1) ZA857987B (esLanguage)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1224546B (it) * 1988-09-29 1990-10-04 Polifarma Spa Utilizzatore farmaceutica di acido 3 -indolpiruvico come agente inibitore di patologie degenerative
JPH06501448A (ja) * 1989-12-26 1994-02-17 ノバ　ファーマシューティカル　コーポレイション 無水物プロドラッグ組成物
US5222109A (en) * 1990-12-28 1993-06-22 Ibm Corporation Endurance management for solid state files
US5436265A (en) * 1993-11-12 1995-07-25 Merck Frosst Canada, Inc. 1-aroyl-3-indolyl alkanoic acids and derivatives thereof useful as anti-inflammatory agents
GB9716657D0 (en) * 1997-08-07 1997-10-15 Zeneca Ltd Chemical compounds
US7113432B2 (en) 2000-09-14 2006-09-26 Sandisk Corporation Compressed event counting technique and application to a flash memory system
US6345001B1 (en) 2000-09-14 2002-02-05 Sandisk Corporation Compressed event counting technique and application to a flash memory system

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2740852A1 (de) * 1977-09-10 1979-03-29 Troponwerke Gmbh & Co Kg Basische 1-acylindol-3-acetocyessigsaeureester, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3468907A (en) * 1967-04-10 1969-09-23 Schering Corp Glyceryl esters of alpha-(1-aroyl-3-indolyl)alkanoic acids
US3966956A (en) * 1972-07-14 1976-06-29 Troponwerke Dinklage & Company [1-(P-Chlorobenzoyl)-5-methoxy-2-methyl-3-indole]acetoxyacetic acid and salts in treating inflammation
US4104278A (en) * 1972-11-25 1978-08-01 Troponwerke Dinklage & Co. Process for the production of compounds with antiphlogistic activity
DE3206888A1 (de) * 1982-02-26 1983-09-15 Troponwerke GmbH & Co KG, 5000 Köln Verfahren zur herstellung von 1-(4-chlorbenzoyl)-5-methoxy-2-methyl-3-indolacetoxyessigsaeure

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2740852A1 (de) * 1977-09-10 1979-03-29 Troponwerke Gmbh & Co Kg Basische 1-acylindol-3-acetocyessigsaeureester, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
ES548067A0 (es) 1987-02-16
US4868201A (en) 1989-09-19
DE3569196D1 (en) 1989-05-11
EP0179428B1 (en) 1989-04-05
JPS6313985B2 (esLanguage) 1988-03-29
EP0179428A2 (en) 1986-04-30
AU4857385A (en) 1986-05-01
CA1287625C (en) 1991-08-13
ES8703423A1 (es) 1987-02-16
EP0179428A3 (en) 1986-07-16
KR860003218A (ko) 1986-05-21
JPS61100565A (ja) 1986-05-19
ZA857987B (en) 1987-06-24
ATE41867T1 (de) 1989-04-15

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