AU569064B2 - Leukotriene antagonists - Google Patents

Leukotriene antagonists

Info

Publication number
AU569064B2
AU569064B2 AU25352/84A AU2535284A AU569064B2 AU 569064 B2 AU569064 B2 AU 569064B2 AU 25352/84 A AU25352/84 A AU 25352/84A AU 2535284 A AU2535284 A AU 2535284A AU 569064 B2 AU569064 B2 AU 569064B2
Authority
AU
Australia
Prior art keywords
leukotriene antagonists
leukotriene
antagonists
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU25352/84A
Other languages
English (en)
Other versions
AU2535284A (en
Inventor
John Gerald Gleason
Ralph Floyd Hall
Thomas Wen-Fu Ku
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/472,772 external-priority patent/US4533747A/en
Priority claimed from US06/472,774 external-priority patent/US4552893A/en
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of AU2535284A publication Critical patent/AU2535284A/en
Application granted granted Critical
Publication of AU569064B2 publication Critical patent/AU569064B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/14—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/38—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D303/40—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by ester radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU25352/84A 1983-03-07 1984-03-07 Leukotriene antagonists Ceased AU569064B2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US47277383A 1983-03-07 1983-03-07
US472774 1983-03-07
US472772 1983-03-07
US06/472,772 US4533747A (en) 1983-03-07 1983-03-07 Leukotriene antagonists intermediates
US06/472,774 US4552893A (en) 1983-03-07 1983-03-07 Leukotriene antagonists
US472773 1983-03-07

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU82121/87A Division AU587922B2 (en) 1983-03-07 1987-12-04 Leukotriene antagonists

Publications (2)

Publication Number Publication Date
AU2535284A AU2535284A (en) 1984-09-13
AU569064B2 true AU569064B2 (en) 1988-01-21

Family

ID=27413217

Family Applications (2)

Application Number Title Priority Date Filing Date
AU25352/84A Ceased AU569064B2 (en) 1983-03-07 1984-03-07 Leukotriene antagonists
AU82121/87A Ceased AU587922B2 (en) 1983-03-07 1987-12-04 Leukotriene antagonists

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU82121/87A Ceased AU587922B2 (en) 1983-03-07 1987-12-04 Leukotriene antagonists

Country Status (7)

Country Link
EP (1) EP0121350B1 (OSRAM)
AU (2) AU569064B2 (OSRAM)
DE (1) DE3463653D1 (OSRAM)
DK (1) DK130984A (OSRAM)
ES (1) ES8604134A1 (OSRAM)
GR (1) GR79832B (OSRAM)
PT (1) PT78196B (OSRAM)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4623535A (en) * 1984-01-19 1986-11-18 Smithkline Beckman Corporation Leukotriene antagonists
EP0170048B1 (de) * 1984-06-28 1991-04-17 Ciba-Geigy Ag Aliphatische Thioether
US4798842A (en) * 1984-07-18 1989-01-17 Schering Corporation Inhibitors of slow reacting substance of anaphylaxis
US4889873A (en) * 1984-07-18 1989-12-26 Schering Corporation Inhibitors of slow reacting substance of anaphylaxis
US4988716A (en) * 1984-07-18 1991-01-29 Schering Corporation Inhibitors of slow reacting substance of anaphylaxis
US4758594A (en) * 1984-07-18 1988-07-19 Schering Corporation Inhibitors of slow reacting substance of anaphylaxis
US4808572A (en) * 1985-12-06 1989-02-28 Ciba-Geigy Corporation α-Hydroxy thioethers
FR2660655A1 (fr) * 1990-04-09 1991-10-11 Fournier Sca Laboratoires Antagonistes de leucotrienes, leur procede de preparation et leur utilisation en therapeutique.
AR040956A1 (es) 2002-07-31 2005-04-27 Schering Ag Nuevos conjugados de efectores, procedimientos para su preparacion y su uso farmaceutico
WO2004012735A2 (en) * 2002-07-31 2004-02-12 Schering Ag New effector conjugates, process for their production and their pharmaceutical use

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4311645A (en) * 1980-03-24 1982-01-19 Hoffmann-La Roche Inc. Synthesis of SRS-active compounds
US4461775A (en) * 1982-08-02 1984-07-24 Mcneilab, Inc. Hydroxythioether fatty acid derivatives
US4469705A (en) * 1982-08-02 1984-09-04 Mcneilab, Inc. Saturated leukotriene derivatives as antiallergens

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4513005A (en) * 1981-06-18 1985-04-23 Lilly Industries Limited SRS-A antagonists

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4311645A (en) * 1980-03-24 1982-01-19 Hoffmann-La Roche Inc. Synthesis of SRS-active compounds
US4461775A (en) * 1982-08-02 1984-07-24 Mcneilab, Inc. Hydroxythioether fatty acid derivatives
US4469705A (en) * 1982-08-02 1984-09-04 Mcneilab, Inc. Saturated leukotriene derivatives as antiallergens

Also Published As

Publication number Publication date
PT78196A (en) 1984-04-01
EP0121350A2 (en) 1984-10-10
ES8604134A1 (es) 1986-01-16
ES530310A0 (es) 1986-01-16
EP0121350A3 (en) 1985-01-23
AU2535284A (en) 1984-09-13
GR79832B (OSRAM) 1984-10-31
AU8212187A (en) 1988-03-31
DK130984A (da) 1984-09-08
DE3463653D1 (en) 1987-06-19
EP0121350B1 (en) 1987-05-13
PT78196B (en) 1986-04-24
AU587922B2 (en) 1989-08-31
DK130984D0 (da) 1984-02-29

Similar Documents

Publication Publication Date Title
AU572806B2 (en) Leukotriene antagonists
AU561591B2 (en) line
AU575575B2 (en) Leukotriene antagonist compounds and intermediates
AU566154B2 (en) Substituted indenopyridazones
EP0140684A3 (en) Leukotriene antagonists
AU2809484A (en) N-pyridylindoles
AU3503084A (en) Omstallbar trappa
DE3464903D1 (en) Leukotriene antagonists
AU587922B2 (en) Leukotriene antagonists
AU588004B2 (en) V1-vasopressin antagonists
AU560255B2 (en) Substituted indoles
AU560314B2 (en) Substituted 3-amino-1-h-pyrazoles
AU2952484A (en) 6-deoxyanthracyclines
ZA841657B (en) Leukotriene antagonists
AU3688484A (en) Silicophosphoaluminate-mcm10
AU3677184A (en) Vatskevarmare
AU571635B2 (en) Leukotriene antagonists
AU2622884A (en) Substituted phenoxyanilines
AU2954689A (en) Leukotriene antagonists
AU2282283A (en) Hairwashing collar
AU2977184A (en) Desacetyl ravidomycin
AU4075285A (en) Substituted fluoro-acetanilides
AU2377084A (en) 1-substituted - triazolobenzodiazepines
IE850119L (en) Leukotriene antagonists
ZA85419B (en) Leukotriene antagonists