AU5596600A - Treating smooth muscle hyperactivity with (r)-oxybutynin and (r)- desethyloxybutynin - Google Patents
Treating smooth muscle hyperactivity with (r)-oxybutynin and (r)- desethyloxybutyninInfo
- Publication number
- AU5596600A AU5596600A AU5596600A AU5596600A AU5596600A AU 5596600 A AU5596600 A AU 5596600A AU 5596600 A AU5596600 A AU 5596600A AU 5596600 A AU5596600 A AU 5596600A AU 5596600 A AU5596600 A AU 5596600A
- Authority
- AU
- Australia
- Prior art keywords
- oxybutynin
- smooth muscle
- desethyloxybutynin
- muscle hyperactivity
- optically pure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 208000013403 hyperactivity Diseases 0.000 title abstract 4
- 210000002460 smooth muscle Anatomy 0.000 title abstract 4
- XIQVNETUBQGFHX-QFIPXVFZSA-N (R)-oxybutynin Chemical compound C1([C@](O)(C(=O)OCC#CCN(CC)CC)C=2C=CC=CC=2)CCCCC1 XIQVNETUBQGFHX-QFIPXVFZSA-N 0.000 title 1
- XIQVNETUBQGFHX-UHFFFAOYSA-N Ditropan Chemical compound C=1C=CC=CC=1C(O)(C(=O)OCC#CCN(CC)CC)C1CCCCC1 XIQVNETUBQGFHX-UHFFFAOYSA-N 0.000 abstract 3
- SNIBJKHIKIIGPR-UHFFFAOYSA-N N-desethyloxybutynin Chemical compound C=1C=CC=CC=1C(O)(C(=O)OCC#CCNCC)C1CCCCC1 SNIBJKHIKIIGPR-UHFFFAOYSA-N 0.000 abstract 3
- 229960005434 oxybutynin Drugs 0.000 abstract 3
- 206010046543 Urinary incontinence Diseases 0.000 abstract 1
- 230000001078 anti-cholinergic effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 208000002551 irritable bowel syndrome Diseases 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 230000002048 spasmolytic effect Effects 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 210000003932 urinary bladder Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Virology (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2000/015515 WO2001093683A1 (en) | 2000-06-07 | 2000-06-07 | Treating smooth muscle hyperactivity with (r)-oxybutynin and (r)- desethyloxybutynin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU5596600A true AU5596600A (en) | 2001-12-17 |
Family
ID=21741461
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU5596600A Pending AU5596600A (en) | 2000-06-07 | 2000-06-07 | Treating smooth muscle hyperactivity with (r)-oxybutynin and (r)- desethyloxybutynin |
| AU2000255966A Expired AU2000255966B2 (en) | 2000-06-07 | 2000-06-07 | Treating smooth muscle hyperactivity with (r)-oxybutynin and (r)- desethyloxybutynin |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2000255966A Expired AU2000255966B2 (en) | 2000-06-07 | 2000-06-07 | Treating smooth muscle hyperactivity with (r)-oxybutynin and (r)- desethyloxybutynin |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1286591B1 (enExample) |
| JP (1) | JP5684964B2 (enExample) |
| CN (3) | CN101108176A (enExample) |
| AT (1) | ATE483459T1 (enExample) |
| AU (2) | AU5596600A (enExample) |
| CA (1) | CA2378754A1 (enExample) |
| DE (1) | DE60045082D1 (enExample) |
| ES (1) | ES2350330T3 (enExample) |
| WO (1) | WO2001093683A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002241721A1 (en) * | 2001-12-21 | 2003-09-02 | Bridge Pharma, Inc. | A non-arrhythmogenic metabolite of oxybutynin |
| EP1424079A1 (en) * | 2002-11-27 | 2004-06-02 | Boehringer Ingelheim International GmbH | Combination of a beta-3-receptor agonist and of a reuptake inhibitor of serotonin and/or norepinephrine |
| PT1629850E (pt) * | 2004-08-24 | 2007-08-14 | Nutricia Nv | Composição nutricional que compreende a administração de oligossacarídeos indigeríveis |
| US8920392B2 (en) | 2009-05-05 | 2014-12-30 | Watson Laboratories, Inc. | Method for treating overactive bladders and a device for storage and administration of topical oxybutynin compositions |
| US9370528B2 (en) | 2011-03-02 | 2016-06-21 | Volant Holdings Gmbh | Compositions, methods of treatment and diagnostics for treatment of hepatic steatosis alone or in combination with a hepatitis C virus infection |
| US10349884B2 (en) | 2011-06-03 | 2019-07-16 | Sighpath Pharma Inc. | Liposomal mitigation of drug-induced inhibition of the cardiac ikr channel |
| US10117881B2 (en) | 2011-06-03 | 2018-11-06 | Signpath Pharma, Inc. | Protective effect of DMPC, DMPG, DMPC/DMPG, LYSOPG and LYSOPC against drugs that cause channelopathies |
| US12004868B2 (en) | 2011-06-03 | 2024-06-11 | Signpath Pharma Inc. | Liposomal mitigation of drug-induced inhibition of the cardiac IKr channel |
| US10238602B2 (en) | 2011-06-03 | 2019-03-26 | Signpath Pharma, Inc. | Protective effect of DMPC, DMPG, DMPC/DMPG, LysoPG and LysoPC against drugs that cause channelopathies |
| US10449193B2 (en) | 2011-06-03 | 2019-10-22 | Signpath Pharma Inc. | Protective effect of DMPC, DMPG, DMPC/DMPG, lysoPG and lysoPC against drugs that cause channelopathies |
| WO2012167212A2 (en) | 2011-06-03 | 2012-12-06 | Signpath Pharma Inc. | Liposomal mitigation of drug-induced long qt syndrome and potassium delayed-rectifier current |
| US20160151321A1 (en) | 2012-11-13 | 2016-06-02 | Dinesh C. Patel | Methods for the treatment of sialorrhea |
| US20140135392A1 (en) * | 2012-11-13 | 2014-05-15 | NeuRx Pharmaceuticals LLC | Methods for the treatment of sialorrhea |
| CN103169660B (zh) * | 2013-04-15 | 2015-04-08 | 石正国 | 一种制备高包封率的利巴韦林脂质体口服乳 |
| WO2015095576A1 (en) * | 2013-12-18 | 2015-06-25 | Signpath Pharma, Inc. | Liposomal mitigation of drug-induced inhibition of the cardiac ikr channel |
| EP3207931A3 (en) | 2014-06-03 | 2017-12-20 | Signpath Pharma Inc. | Protective effect of dmpc, dmpg, dmpc/dmpg, egpg, lysopg and lysopc against drugs that cause channelopathies |
| KR102638618B1 (ko) | 2016-04-27 | 2024-02-21 | 사인패스 파마 인코포레이티드 | 약물 유발된 방실 차단의 방지 |
| CR20220617A (es) * | 2020-05-05 | 2023-02-09 | Apnimed Inc | Formas polimórficas de clorhidrato de (r)-oxibutinina |
| AU2021298896A1 (en) * | 2020-07-03 | 2023-02-16 | Phoxbio Limited | Reduction of viral infections |
| CN117396460A (zh) * | 2021-05-04 | 2024-01-12 | 爱普宁公司(特拉华) | (r)-奥昔布宁d-苹果酸盐的固体形式 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4008269A (en) * | 1970-05-05 | 1977-02-15 | William H. Rorer, Inc. | Phenylacetic acids |
| IT1231237B (it) * | 1987-09-21 | 1991-11-26 | Angeli Inst Spa | Derivati eterociclici |
| US5677346A (en) * | 1995-01-31 | 1997-10-14 | Sepracor, Inc. | Treating urinary incontinence using (S)-desethyloxybutynin |
| US5973182A (en) * | 1998-10-22 | 1999-10-26 | Sepracor Inc. | Carbonate Intermediates useful in the preparation of optically active cyclohexylphenylglycolate esters |
-
2000
- 2000-06-07 WO PCT/US2000/015515 patent/WO2001093683A1/en not_active Ceased
- 2000-06-07 CA CA002378754A patent/CA2378754A1/en not_active Abandoned
- 2000-06-07 AU AU5596600A patent/AU5596600A/xx active Pending
- 2000-06-07 AT AT00941235T patent/ATE483459T1/de not_active IP Right Cessation
- 2000-06-07 CN CNA2007101418683A patent/CN101108176A/zh active Pending
- 2000-06-07 JP JP2002501260A patent/JP5684964B2/ja not_active Expired - Fee Related
- 2000-06-07 EP EP00941235A patent/EP1286591B1/en not_active Expired - Lifetime
- 2000-06-07 CN CN00819623A patent/CN1454054A/zh active Pending
- 2000-06-07 AU AU2000255966A patent/AU2000255966B2/en not_active Expired
- 2000-06-07 DE DE60045082T patent/DE60045082D1/de not_active Expired - Lifetime
- 2000-06-07 ES ES00941235T patent/ES2350330T3/es not_active Expired - Lifetime
-
2003
- 2003-05-16 CN CN03131438A patent/CN1451388A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2378754A1 (en) | 2001-12-13 |
| AU2000255966B2 (en) | 2005-03-24 |
| ES2350330T3 (es) | 2011-01-21 |
| AU2000255966A1 (en) | 2002-03-07 |
| EP1286591A4 (en) | 2007-04-04 |
| ATE483459T1 (de) | 2010-10-15 |
| EP1286591B1 (en) | 2010-10-06 |
| JP5684964B2 (ja) | 2015-03-18 |
| CN1454054A (zh) | 2003-11-05 |
| CN101108176A (zh) | 2008-01-23 |
| DE60045082D1 (de) | 2010-11-18 |
| EP1286591A1 (en) | 2003-03-05 |
| CN1451388A (zh) | 2003-10-29 |
| WO2001093683A1 (en) | 2001-12-13 |
| JP2003535110A (ja) | 2003-11-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP1286591A4 (en) | TREATMENT OF OVERACTIVITY OF SMOOTH MUSCULATORY WITH (R) -OXYBUTYNIN AND (R) -DESETHYLOXYBUTYNIN | |
| AU2001249091A1 (en) | Novel methods using cholinesterase inhibitors | |
| TWI347657B (en) | Ultra-thin, high quality strained silicon-on-insulator formed by elastic strain transfer | |
| CA2534682A1 (en) | Capped pyrazinoylguanidine sodium channel blockers | |
| DE122007000065I1 (de) | 3,3-Diphenylpropylaminderivate | |
| EP1352897A3 (en) | Adamantane derivatives for the treatment of inflammatory, immune and cardiovascular diseases | |
| AU2001283963A1 (en) | Polysiloxane polymers, method for their production and the use thereof | |
| EP2281568A3 (en) | Uses of soluble CTLA4 mutant molecules | |
| IL162461A0 (en) | Polymorphs of clopidogrel hydrogensulfate | |
| PL363081A1 (en) | Growth hormone secretagogues | |
| DK0806948T3 (da) | Behandling af urininkontinens ved anvendelse af (S)-oxybutynin og (S)-desethyloxybutynin | |
| WO2006013268A3 (fr) | Nouveaux copolymeres ethyleniques, compositions les comprenant et procede de traitement | |
| PL335254A1 (en) | Methods of treating vomiting and central nervous system disorders by means ogf(+) norcisapride | |
| WO2005070390A3 (en) | Mitratapide oral solution | |
| WO2003084928A8 (en) | Alpha, omega-dicarboximide derivatives as useful uro-selective α1α adrenoceptor blockers | |
| WO2000047547A3 (en) | Cycloalkyl amine compounds and uses thereof | |
| MXPA05011699A (es) | Inhibidores de la bomba de protones para el tratamiento de trastornos del abdomen inferior. | |
| BG105097A (en) | Use of optically pure(-)norcisapride in the treatment of apnea, bulimia, and other disorders | |
| AU2001243281A1 (en) | A process for preparing hydrogenated aromatic polymers | |
| MY144089A (en) | A medicament related to mirtazapine for the treatment of hot flush | |
| AU2002254947A1 (en) | Kappa opiate agonists for the treatment of bladder diseases | |
| EP1374693A3 (en) | Method for preventing decrease of breast milk amount in mammals | |
| SE0103795D0 (sv) | Compounds and method for the treatment of överactive bladder | |
| MXPA03006742A (es) | Uso de buprenorfina para la terapia de la incontinencia urinaria. | |
| MXPA04002492A (es) | Uso novedoso de aminometil cromanos sustituidos. |