AU4997399A - Module and method for introducing a sample into a chromatography column - Google Patents

Module and method for introducing a sample into a chromatography column

Info

Publication number
AU4997399A
AU4997399A AU49973/99A AU4997399A AU4997399A AU 4997399 A AU4997399 A AU 4997399A AU 49973/99 A AU49973/99 A AU 49973/99A AU 4997399 A AU4997399 A AU 4997399A AU 4997399 A AU4997399 A AU 4997399A
Authority
AU
Australia
Prior art keywords
sample
module
chromatography column
introducing
chromatography
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU49973/99A
Other languages
English (en)
Inventor
Ivan Hargro
Jeffrey A. Horsman
Peter C. Rahn
Peter C. Van Davelaar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dyax Corp
Original Assignee
Dyax Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22476620&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU4997399(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Dyax Corp filed Critical Dyax Corp
Publication of AU4997399A publication Critical patent/AU4997399A/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • G01N30/6026—Fluid seals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/14—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the introduction of the feed to the apparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • G01N30/6017—Fluid distributors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6091—Cartridges
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G01N30/08—Preparation using an enricher
    • G01N2030/085—Preparation using an enricher using absorbing precolumn
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/16—Injection
    • G01N2030/167—Injection on-column injection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/50—Conditioning of the sorbent material or stationary liquid
    • G01N30/52—Physical parameters
    • G01N2030/522—Physical parameters pressure
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • G01N30/6021—Adjustable pistons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6052—Construction of the column body
    • G01N30/6069—Construction of the column body with compartments or bed substructure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Sampling And Sample Adjustment (AREA)
AU49973/99A 1998-08-20 1999-07-14 Module and method for introducing a sample into a chromatography column Abandoned AU4997399A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/137,278 US6139733A (en) 1998-08-20 1998-08-20 Module and method for introducing a sample into a chromatography column
US09137278 1998-08-20
PCT/US1999/016010 WO2000010676A1 (en) 1998-08-20 1999-07-14 Module and method for introducing a sample into a chromatography column

Publications (1)

Publication Number Publication Date
AU4997399A true AU4997399A (en) 2000-03-14

Family

ID=22476620

Family Applications (1)

Application Number Title Priority Date Filing Date
AU49973/99A Abandoned AU4997399A (en) 1998-08-20 1999-07-14 Module and method for introducing a sample into a chromatography column

Country Status (8)

Country Link
US (3) US6139733A (https=)
EP (1) EP1113849B1 (https=)
JP (1) JP4328898B2 (https=)
AT (1) ATE406947T1 (https=)
AU (1) AU4997399A (https=)
DE (1) DE69939479D1 (https=)
ES (1) ES2313788T3 (https=)
WO (1) WO2000010676A1 (https=)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6436284B1 (en) * 1997-11-12 2002-08-20 Biotage, Inc. Chromatography apparatus
US20030217973A1 (en) * 1998-08-20 2003-11-27 Horsman Jeffrey A. Method for introducing a sample into a chromatography column
US6679989B2 (en) * 2001-06-01 2004-01-20 Agilent Technologies, Inc. Integral, thru-bore, direct coupled high pressure liquid chromatography guard column
US6880576B2 (en) 2001-06-07 2005-04-19 Nanostream, Inc. Microfluidic devices for methods development
US20020187557A1 (en) * 2001-06-07 2002-12-12 Hobbs Steven E. Systems and methods for introducing samples into microfluidic devices
CA2472945A1 (en) * 2002-02-13 2003-08-21 Nanostream, Inc. Microfluidic separation column devices and fabrication methods
US7261812B1 (en) 2002-02-13 2007-08-28 Nanostream, Inc. Multi-column separation devices and methods
US6649051B1 (en) 2002-05-01 2003-11-18 Biotage, Inc. Processing of chemicals in flow-through device with porous media
US20030205456A1 (en) * 2002-05-01 2003-11-06 Jamalabadi Shahnaz Ghassemi Processing of chemicals in flow-through device with porous media
KR100505361B1 (ko) * 2002-06-03 2005-08-03 정원조 소결 무기 분말 프릿이 장착된 금속 튜빙/프릿 및 이를이용하여 제작하는 크로마토그래피 컬럼
US20040142488A1 (en) * 2002-07-15 2004-07-22 Gierde Douglas T. Method and device for extracting an analyte
EP1521637B1 (en) * 2002-07-15 2011-10-19 Phynexus, Inc. Extraction column device
US6783673B2 (en) * 2002-08-23 2004-08-31 Biotage, Inc. Composite chromatography column
AU2003265996A1 (en) 2002-09-10 2004-04-30 Waters Investments Limited A chromatographic column and methods for controlling sorbent density
US6936167B2 (en) * 2002-10-31 2005-08-30 Nanostream, Inc. System and method for performing multiple parallel chromatographic separations
WO2004047948A1 (en) * 2002-11-26 2004-06-10 Prime Separations, Incorporated Chromatographic separation processes and apparatus
WO2004058379A1 (en) * 2002-12-17 2004-07-15 Biotage,Inc. Processing of chemicals in flow-through device porous media
US7887754B2 (en) * 2003-02-07 2011-02-15 Waters Technologies Corporation Polymeric solid supports for chromatography nanocolumns
JP4722830B2 (ja) * 2003-02-10 2011-07-13 ウオーターズ・テクノロジーズ・コーポレイシヨン クロマトグラフィー分離および抽出用シロキサン固定化粒子状固定相
WO2005007264A2 (en) * 2003-07-14 2005-01-27 Waters Investments Limited Separation device with integral guard column
US7943393B2 (en) * 2003-07-14 2011-05-17 Phynexus, Inc. Method and device for extracting an analyte
US20050011821A1 (en) * 2003-07-17 2005-01-20 Sigma-Aldrich Co. High throughput flash purification stand and cartridge
US20050011835A1 (en) * 2003-07-17 2005-01-20 Sigma-Aldrich Co. High throughput flash purification stand and cartridge
US20050032238A1 (en) * 2003-08-07 2005-02-10 Nanostream, Inc. Vented microfluidic separation devices and methods
US7028536B2 (en) * 2004-06-29 2006-04-18 Nanostream, Inc. Sealing interface for microfluidic device
US7404893B2 (en) * 2003-10-17 2008-07-29 Varian, Inc. Chromatography cartridge and method for manufacturing a chromatography cartridge
US7351332B2 (en) * 2003-10-17 2008-04-01 Varian, Inc. Chromatography cartridge and method for manufacturing a chromatography cartridge
WO2005087339A1 (en) * 2004-03-04 2005-09-22 Sigma-Aldrich Co. A high throughput flash purification stand and cartridge
US20050247625A1 (en) * 2004-05-05 2005-11-10 Jianbo Liu Determining conditions for chromatography
US7686959B2 (en) 2004-05-05 2010-03-30 Biotage Ab Control system and method for flash separation
US7138061B2 (en) * 2004-05-10 2006-11-21 Scientific Plastic Products, Inc. Flash chromatography cartridge
GB2434556B (en) * 2004-08-19 2010-09-29 Waters Investments Ltd Devices, assemblies and systems for performing separations
US7348526B2 (en) * 2004-08-20 2008-03-25 Cem Corporation Microwave-assisted chromatography preparation
US7674383B2 (en) * 2005-10-25 2010-03-09 Phenomenex, Inc. Method and apparatus for packing chromatography columns
US7670487B2 (en) * 2006-07-21 2010-03-02 Wikfors Edwin E De-pressurization scheme for chromatography columns
KR20130083490A (ko) * 2007-12-05 2013-07-22 올테크 어소시에이츠, 인크. 시료를 분석하고 시료 분획을 수집하기 위한 방법 및 장치
SG171929A1 (en) 2008-12-04 2011-07-28 Alltech Associates Inc Methods and apparatus for moving aliquot samples of fluid
WO2010068276A1 (en) 2008-12-10 2010-06-17 Alltech Associates Inc. Chromatography systems and system components
EP2204225A1 (en) * 2008-12-22 2010-07-07 SynChro GmbH Column reactor
US8314934B2 (en) 2009-09-01 2012-11-20 Alltech Associates, Inc. Methods and apparatus for analyzing samples and collecting sample fractions
FR2967916B3 (fr) * 2010-11-30 2012-12-21 Biotage Ab Ensemble colonne de chromatographie et procede de production dudit ensemble colonne de chromatographie
JP5879592B2 (ja) * 2011-12-26 2016-03-08 東京理化器械株式会社 カラム

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2008354A1 (de) * 1970-02-23 1971-09-09 Boehnnger Mannheim GmbH, 6800 Mann heim Kombinationssaule
US3266554A (en) * 1963-11-29 1966-08-16 Possis Machine Corp Apparatus for preparing specimens for chromatographic analysis
US3398512A (en) * 1966-04-18 1968-08-27 Continental Oil Co Chromatography apparatus
DE1801684B2 (de) * 1967-10-09 1971-12-23 Czeskoslovenska Akademie Ved., Prag Einrichtung zum durchfuehren einer chemischen reaktion eines in der form von einzelnen konzentrationszonen in einem traeger medium vorliegenden stoffes
US3682315A (en) * 1969-10-20 1972-08-08 Wolfgang Haller Cartridge type column for treatment of liquid streams and substrate enclosure therefor
US3692669A (en) * 1970-08-10 1972-09-19 California Inst Of Techn Method and apparatus for micro dry column chromatography
US3902849A (en) * 1971-08-19 1975-09-02 Medi Physics Inc Radioisotope and radiopharmaceutical generators
US4093550A (en) * 1975-06-04 1978-06-06 Riedel-De Haen Aktiengesellschaft Column for high pressure liquid chromatography
US4250035A (en) * 1978-11-13 1981-02-10 Waters Associates, Inc. Radial compression of packed beds
US4565532A (en) 1981-02-18 1986-01-21 Kaama Marine Engineering, Inc. Stern drive
CA1193975A (en) * 1981-06-19 1985-09-24 Stanislav Vozka Column for liquid chromatography
US4457846A (en) * 1982-07-08 1984-07-03 Milton Roy Company Liquid chromatography methods and devices
US4483374A (en) * 1982-11-01 1984-11-20 Ethyl Corporation Chromatographic column
DE3436095A1 (de) * 1984-10-02 1986-04-10 Merck Patent Gmbh, 6100 Darmstadt Chromatographiesaeule
US4636316A (en) * 1985-01-11 1987-01-13 Beckman Instruments, Inc. Disposable column cartridge
US4565632A (en) * 1985-01-11 1986-01-21 Beckman Instruments, Inc. Chromatographic cartridge column system
US4719011A (en) * 1985-03-22 1988-01-12 H. T. Chemicals, Inc. High pressure liquid chromatography columns
US4876005A (en) * 1988-02-12 1989-10-24 The Perkin-Elmer Corporation High pressure column assembly for a liquid chromatograph system
US5227059A (en) * 1989-11-08 1993-07-13 Alltech Associates, Inc. Chromatography columns
US5614089A (en) * 1990-07-13 1997-03-25 Isco, Inc. Apparatus and method for supercritical fluid extraction or supercritical fluid chromatography
US5234599A (en) * 1990-10-09 1993-08-10 The Dow Chemical Company On-line multidimensional chromatographic system with large volume injection handling for supercritical fluid chromatography
EP0545843B1 (en) * 1991-12-03 1995-08-16 Tracer Analitica S.L. Fixing arrangement for chromatography columns
US5338448A (en) * 1992-10-16 1994-08-16 Sarasep, Inc. Method of preventing contamination of a chromatography column
EP0754085B1 (en) * 1994-04-07 1999-09-29 Dyax Corp. Apparatus for pressurizing a removable chromatography cartridge
US5462660A (en) * 1994-04-22 1995-10-31 The United States Of America As Represented By The Secretary Of Agriculture High performance liquid chromatography injection system for the simultaneous concentration and analysis of trace components

Also Published As

Publication number Publication date
JP4328898B2 (ja) 2009-09-09
DE69939479D1 (de) 2008-10-16
JP2002523728A (ja) 2002-07-30
EP1113849A1 (en) 2001-07-11
US6294087B1 (en) 2001-09-25
ES2313788T3 (es) 2009-03-01
US6139733A (en) 2000-10-31
ATE406947T1 (de) 2008-09-15
WO2000010676A1 (en) 2000-03-02
EP1113849A4 (en) 2001-10-17
US6221252B1 (en) 2001-04-24
EP1113849B1 (en) 2008-09-03

Similar Documents

Publication Publication Date Title
AU4997399A (en) Module and method for introducing a sample into a chromatography column
AU5156096A (en) Improvements in or relating to sample processing
US6200533B1 (en) Solid phase extraction plate with silica disks
WO2004033059A3 (en) Methods and apparatus for optophoretic diagnosis of cells and particles
WO2003042788A3 (en) A system for tracking biological samples
EP0753154A1 (en) Analysis method and analysis apparatus
AU2751199A (en) Method, apparatus and flow cell for high sensitivity detection of fluorescent molecules
AU3371395A (en) Biological specimen analysis system processing integrity checking apparatus
AU5657096A (en) Molecular imaging
AU2907495A (en) Method and apparatus for automated chemical analysis with variable reagents
WO1999025476A3 (en) Assay work station
WO2000050872A3 (en) A system for cell-based screening
WO2003052141A3 (en) High troughput analysis and detection of multiple target sequences using circular probes
WO2000026408A3 (en) A system for cell-based screening
WO1999054441A8 (en) Efficient purification of adenovirus
DK0891221T3 (da) Membranmodul til et anlæg til membranadskillelse
DE69210687D1 (de) Probensammel- und Einlasssystem für Gaschromatographen
IL112944A (en) Flow-through bioreactor with grooves for cell retention
EP0359900A3 (en) Process for separating highly molecular substances from liquid culture media, and device for carrying out the process
SE9903886L (sv) Vätske-vätskeextraktion och direkt överföring av analyten till gaskromatografiapparat
AU4485896A (en) Process and dna molecules for increasing the photosynthesis rate in plants
CA2294749A1 (en) One step device and process for concentration and purification of biological molecules
ATE200303T1 (de) Verfahren und vorrichtung zur schnellen trennung und/oder umwandlung von substraten
AT388563B (de) Vorrichtung zum verarbeiten von fliessfaehigen medien, insbesondere zur fermentation von mikroorganismen
WO2000070344A3 (en) Method for increasing the efficiency of experimental fractionation in activity profiling of compound mixtures

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase