AU4990697A - Methods of reducing the levels of protoporphyrin ix in recombinant hemoglobin preparations - Google Patents

Methods of reducing the levels of protoporphyrin ix in recombinant hemoglobin preparations

Info

Publication number
AU4990697A
AU4990697A AU49906/97A AU4990697A AU4990697A AU 4990697 A AU4990697 A AU 4990697A AU 49906/97 A AU49906/97 A AU 49906/97A AU 4990697 A AU4990697 A AU 4990697A AU 4990697 A AU4990697 A AU 4990697A
Authority
AU
Australia
Prior art keywords
protoporphyrin
levels
reducing
methods
recombinant hemoglobin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU49906/97A
Other languages
English (en)
Inventor
Elaine A. Best
Christopher C. Frye
Charles L Hershberger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Somatogen Inc
Eli Lilly and Co
Original Assignee
Somatogen Inc
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Somatogen Inc, Eli Lilly and Co filed Critical Somatogen Inc
Publication of AU4990697A publication Critical patent/AU4990697A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AU49906/97A 1996-10-18 1997-10-17 Methods of reducing the levels of protoporphyrin ix in recombinant hemoglobin preparations Abandoned AU4990697A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2851696P 1996-10-18 1996-10-18
US60028516 1996-10-18
PCT/US1997/018950 WO1998017809A1 (en) 1996-10-18 1997-10-17 Methods of reducing the levels of protoporphyrin ix in recombinant hemoglobin preparations

Publications (1)

Publication Number Publication Date
AU4990697A true AU4990697A (en) 1998-05-15

Family

ID=21843890

Family Applications (1)

Application Number Title Priority Date Filing Date
AU49906/97A Abandoned AU4990697A (en) 1996-10-18 1997-10-17 Methods of reducing the levels of protoporphyrin ix in recombinant hemoglobin preparations

Country Status (6)

Country Link
US (1) US6136565A (https=)
EP (1) EP0954586A1 (https=)
JP (1) JP2001502543A (https=)
AU (1) AU4990697A (https=)
CA (1) CA2268278A1 (https=)
WO (1) WO1998017809A1 (https=)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2268278A1 (en) * 1996-10-18 1998-04-30 Somatogen, Inc. Methods of reducing the levels of protoporphyrin ix in recombinant hemoglobin preparations
GB0000908D0 (en) * 2000-01-14 2000-03-08 Scient Generics Ltd Parallel free-space optical communications
WO2003050240A2 (en) * 2001-12-12 2003-06-19 Eli Lilly And Company Expression system
DE10224750A1 (de) 2002-06-04 2003-12-24 Fresenius Medical Care De Gmbh Vorrichtung zur Behandlung einer medizinischen Flüssigkeit
AU2003282687A1 (en) 2002-10-04 2004-05-04 Genencor International, Inc. Glucose transport mutants for production of biomaterial
US7935074B2 (en) 2005-02-28 2011-05-03 Fresenius Medical Care Holdings, Inc. Cassette system for peritoneal dialysis machine
US8197231B2 (en) 2005-07-13 2012-06-12 Purity Solutions Llc Diaphragm pump and related methods
WO2010040063A1 (en) * 2008-10-03 2010-04-08 The Charlotte-Mecklenburg Hospital Authority D/B/A Carolinas Medical Center Treatment of hepatitis c infection with metalloporphyrins
US8192401B2 (en) 2009-03-20 2012-06-05 Fresenius Medical Care Holdings, Inc. Medical fluid pump systems and related components and methods
CN102497895A (zh) 2009-07-15 2012-06-13 弗雷塞尼斯医疗保健控股公司 医疗流体盒及相关系统和方法
US8720913B2 (en) 2009-08-11 2014-05-13 Fresenius Medical Care Holdings, Inc. Portable peritoneal dialysis carts and related systems
DE102010053973A1 (de) 2010-12-09 2012-06-14 Fresenius Medical Care Deutschland Gmbh Medizinisches Gerät mit einer Heizung
EP2654825B1 (en) 2010-12-20 2017-08-02 Fresenius Medical Care Holdings, Inc. Medical fluid cassettes and related systems and methods
US9624915B2 (en) 2011-03-09 2017-04-18 Fresenius Medical Care Holdings, Inc. Medical fluid delivery sets and related systems and methods
CN103648540B (zh) 2011-04-21 2016-06-01 弗雷塞尼斯医疗保健控股公司 医疗流体泵送系统及相关装置和方法
US9186449B2 (en) 2011-11-01 2015-11-17 Fresenius Medical Care Holdings, Inc. Dialysis machine support assemblies and related systems and methods
US9610392B2 (en) 2012-06-08 2017-04-04 Fresenius Medical Care Holdings, Inc. Medical fluid cassettes and related systems and methods
US9500188B2 (en) 2012-06-11 2016-11-22 Fresenius Medical Care Holdings, Inc. Medical fluid cassettes and related systems and methods
US9561323B2 (en) 2013-03-14 2017-02-07 Fresenius Medical Care Holdings, Inc. Medical fluid cassette leak detection methods and devices
US10117985B2 (en) 2013-08-21 2018-11-06 Fresenius Medical Care Holdings, Inc. Determining a volume of medical fluid pumped into or out of a medical fluid cassette
JP6821598B2 (ja) 2015-12-07 2021-01-27 ザイマージェン インコーポレイテッド Ｃｏｒｙｎｅｂａｃｔｅｒｉｕｍ ｇｌｕｔａｍｉｃｕｍ由来のプロモーター
US11208649B2 (en) 2015-12-07 2021-12-28 Zymergen Inc. HTP genomic engineering platform
US9988624B2 (en) 2015-12-07 2018-06-05 Zymergen Inc. Microbial strain improvement by a HTP genomic engineering platform
EP3478833A4 (en) 2016-06-30 2019-10-02 Zymergen, Inc. METHOD FOR PRODUCING A BACTERIAL HEMOGLOBIN LIBRARY AND ITS USE
JP2019519241A (ja) 2016-06-30 2019-07-11 ザイマージェン インコーポレイテッド グルコース透過酵素ライブラリーを生成するための方法およびその使用
WO2022098745A1 (en) 2020-11-03 2022-05-12 Indi Molecular, Inc. Compositions, delivery systems, and methods useful in tumor therapy

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69028448T2 (de) * 1989-05-10 1997-02-06 Medical Research Council, London Herstellung von Hämoglobin und Analogen davon durch Bakterien oder Hefen
US5545727A (en) * 1989-05-10 1996-08-13 Somatogen, Inc. DNA encoding fused di-alpha globins and production of pseudotetrameric hemoglobin
US5665829A (en) * 1990-02-08 1997-09-09 The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Gt. Britain & Northern Ireland Process for the polymerization of olefinic-containing monomers employing anionic initiators
US5840851A (en) * 1993-07-23 1998-11-24 Plomer; J. Jeffrey Purification of hemoglobin
US5665869A (en) * 1993-11-15 1997-09-09 Somatogen, Inc. Method for the rapid removal of protoporphyrin from protoporphyrin IX-containing solutions of hemoglobin
CA2268278A1 (en) * 1996-10-18 1998-04-30 Somatogen, Inc. Methods of reducing the levels of protoporphyrin ix in recombinant hemoglobin preparations

Also Published As

Publication number Publication date
JP2001502543A (ja) 2001-02-27
US6136565A (en) 2000-10-24
WO1998017809A1 (en) 1998-04-30
EP0954586A1 (en) 1999-11-10
CA2268278A1 (en) 1998-04-30

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