AU476655B2 - Trans-2-prostaglandin analogues - Google Patents

Trans-2-prostaglandin analogues

Info

Publication number
AU476655B2
AU476655B2 AU64071/73A AU6407173A AU476655B2 AU 476655 B2 AU476655 B2 AU 476655B2 AU 64071/73 A AU64071/73 A AU 64071/73A AU 6407173 A AU6407173 A AU 6407173A AU 476655 B2 AU476655 B2 AU 476655B2
Authority
AU
Australia
Prior art keywords
trans
prostaglandin analogues
prostaglandin
analogues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU64071/73A
Other languages
English (en)
Other versions
AU6407173A (en
Inventor
HIROHISA WAKATSUKI and BEMI KORF Related Alt MASAKI HAYASHI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP242773A external-priority patent/JPS5336458B2/ja
Priority claimed from JP12279673A external-priority patent/JPS5653545B2/ja
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Publication of AU6407173A publication Critical patent/AU6407173A/en
Application granted granted Critical
Publication of AU476655B2 publication Critical patent/AU476655B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5407—Acyclic saturated phosphonium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU64071/73A 1972-12-29 1973-12-28 Trans-2-prostaglandin analogues Expired AU476655B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JPJP73/2427 1972-12-29
JP242773A JPS5336458B2 (xx) 1972-12-29 1972-12-29
JPJP73/12279 1973-11-02
JP12279673A JPS5653545B2 (xx) 1973-11-02 1973-11-02

Publications (2)

Publication Number Publication Date
AU6407173A AU6407173A (en) 1975-07-03
AU476655B2 true AU476655B2 (en) 1976-09-30

Family

ID=26335786

Family Applications (1)

Application Number Title Priority Date Filing Date
AU64071/73A Expired AU476655B2 (en) 1972-12-29 1973-12-28 Trans-2-prostaglandin analogues

Country Status (11)

Country Link
US (1) US3931296A (xx)
AU (1) AU476655B2 (xx)
BE (1) BE809169A (xx)
CA (1) CA1026329A (xx)
CH (1) CH605727A5 (xx)
DE (1) DE2365035C2 (xx)
FR (1) FR2212146B1 (xx)
GB (1) GB1416410A (xx)
HK (1) HK14279A (xx)
NL (1) NL7317804A (xx)
SE (1) SE399423B (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4052512A (en) * 1976-01-05 1977-10-04 Ono Pharmaceutical Co., Ltd. Prostaglandin analogues
NL7700010A (nl) * 1972-12-29 1977-07-07 Ono Pharmaceutical Co Prostaglandinederivaten.
GB1482010A (en) * 1974-10-28 1977-08-03 Ono Pharmaceutical Co Prostaglandin analogues
GB1520942A (en) * 1976-02-10 1978-08-09 Ono Pharmaceutical Co Postaglandin analogues
US4165437A (en) * 1976-03-12 1979-08-21 Ono Pharmaceutical Company, Ltd. Δ3 -Prostaglandin analogs
GB1588196A (en) * 1977-06-14 1981-04-15 Ono Pharmaceutical Co Prostaglandin analogues
US4176282A (en) * 1978-03-21 1979-11-27 The Upjohn Company 2-Decarboxy-2-alkylcarbonyl-3,7-inter-m-phenylene-3-oxa-4,5,6-trinor-PGF1 compounds
US4123463A (en) * 1978-03-21 1978-10-31 The Upjohn Company 2-Decarboxy-2-alkylketone prostaglandins
DE2834249A1 (de) * 1978-08-04 1980-02-28 Hoechst Ag Neue prostaglandinderivate in der delta 2-11-desoxy-pgf tief 2 bzw. pge tief 2 -reihe
IT1149877B (it) * 1979-01-25 1986-12-10 Ono Pharmaceutical Co Prodotti intermedi per analoghi della prostaglandina
JPS6036422B2 (ja) * 1979-01-29 1985-08-20 小野薬品工業株式会社 プロスタグランジン類似化合物及びその製造方法
JPS6033429B2 (ja) * 1980-04-28 1985-08-02 小野薬品工業株式会社 プロスタグランジン類似化合物
US5166369A (en) * 1981-05-21 1992-11-24 American Cyanamid Company Precursors and synthesis of D1-(methyl)-16,16-(dimethyl)-11-alpha, 15-alpha, beta-dihydroxy-9-oxo-2,13,-trans, trans-prostadienoates
US4360688A (en) * 1981-05-21 1982-11-23 American Cyanamid Company Precursors and synthesis of d1-(methyl)-16,16-(dimethyl)-11-alpha, 15-alpha, beta-dihydroxy-9-oxo-2,13,-trans, trans-prostadienoates
DE3315356A1 (de) * 1982-04-30 1983-11-17 Ono Pharmaceutical Co. Ltd., Osaka Verwendung von prostaglandinanalogen
JPS595154A (ja) * 1982-06-30 1984-01-12 Ono Pharmaceut Co Ltd プロスタグランジンｄ類似化合物
CN105985370B (zh) * 2015-02-11 2019-06-18 常州博海威医药科技股份有限公司 制备利马前列腺素的关键中间体及其应用
CN105985371B (zh) * 2015-02-11 2019-06-18 常州博海威医药科技股份有限公司 制备利马前列腺素的关键中间体及其应用
DK3456710T3 (da) 2016-05-09 2021-09-13 Agc Inc Nyt prostaglandinderivat
EP3705472B1 (en) 2017-10-31 2023-06-21 AGC Inc. Method for producing prostaglandin derivative

Also Published As

Publication number Publication date
US3931296A (en) 1976-01-06
DE2365035A1 (de) 1974-07-04
GB1416410A (en) 1975-12-03
HK14279A (en) 1979-03-30
SE399423B (sv) 1978-02-13
FR2212146B1 (xx) 1978-07-28
DE2365035C2 (de) 1986-04-24
FR2212146A1 (xx) 1974-07-26
NL7317804A (xx) 1974-07-02
BE809169A (fr) 1974-06-27
CH605727A5 (xx) 1978-10-13
AU6407173A (en) 1975-07-03
CA1026329A (en) 1978-02-14

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